scholarly journals Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells

2019 ◽  
Vol 73 ◽  
pp. 1-6.e6 ◽  
Author(s):  
Kacey L. Guenther ◽  
Patali S. Cheruku ◽  
Ayla Cash ◽  
Richard H. Smith ◽  
Luigi J. Alvarado ◽  
...  
Keyword(s):  
Dna Repair ◽  
Progenitor Cells ◽  
Hematopoietic Stem ◽  
Stem And Progenitor Cells

scholarly journals Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1

Blood ◽  
2014 ◽  
Vol 123 (4) ◽  
pp. 509-519 ◽  
Author(s):  
Bérengère de Laval ◽  
Patrycja Pawlikowska ◽  
Daniela Barbieri ◽  
Corinne Besnard-Guerin ◽  
Alba Cico ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dna Repair ◽  
Hematopoietic Stem Cells ◽  
Progenitor Cells ◽  
Hematopoietic Stem ◽  
Key Points ◽  
Stem And Progenitor Cells ◽  
Common Target

Key Points TPO specifically activates Erk and NF-κB pathways in hematopoietic stem and progenitor cells. Erk and NF-κB cooperate to trigger their common target, Iex-1, and DNA-PK-dependent NHEJ activation in HSPCs upon irradiation.

scholarly journals Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair

Stem Cells ◽  
2018 ◽  
Vol 37 (2) ◽  
pp. 284-294 ◽  
Author(s):  
Anastasia Lomova ◽  
Danielle N. Clark ◽  
Beatriz Campo-Fernandez ◽  
Carmen Flores-Bjurström ◽  
Michael L. Kaufman ◽  
...  
Keyword(s):  
Dna Repair ◽  
Progenitor Cells ◽  
Gene Editing ◽  
Temporal Control ◽  
Hematopoietic Stem ◽  
Stem And Progenitor Cells

Flow cytometric enumeration and immunophenotyping of hematopoietic stem and progenitor cells

2001 ◽  
Vol 38 (2) ◽  
pp. 139-147
Author(s):  
Jan W. Gratama ◽  
D. Robert Sutherland ◽  
Michael Keeney
Keyword(s):  
Progenitor Cells ◽  
Hematopoietic Stem ◽  
Flow Cytometric ◽  
Stem And Progenitor Cells

Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation

Leukemia ◽  
2021 ◽  
Author(s):  
Neta Nevo ◽  
Lizeth-Alejandra Ordonez-Moreno ◽  
Shiri Gur-Cohen ◽  
Francesca Avemaria ◽  
Suditi Bhattacharya ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Hematopoietic Stem ◽  
Stem And Progenitor Cells

3026 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

2020 ◽  
Vol 88 ◽  
pp. S46
Author(s):  
Oakley Olson ◽  
Fernando Calero-Nieto ◽  
Xiaonan Wang ◽  
Bethold Göttgens ◽  
Emmanuelle Passegué
Keyword(s):  
Progenitor Cells ◽  
Metabolic Adaptation ◽  
Hematopoietic Stem ◽  
Stem And Progenitor Cells ◽  
Emergency Myelopoiesis

3008 – OXYGEN TENSION REGULATES CALCIUM SIGNALING AND FUNCTION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS

2020 ◽  
Vol 88 ◽  
pp. S40
Author(s):  
Paige Dausinas ◽  
Jacob Slack ◽  
Christopher Basile ◽  
Anish Karlapudi ◽  
Heather O'Leary
Keyword(s):  
Calcium Signaling ◽  
Progenitor Cells ◽  
Oxygen Tension ◽  
Hematopoietic Stem ◽  
Stem And Progenitor Cells ◽  
And Function
Sign in / Sign up

Export Citation Format

Share Document