Protective effect of Rumex patientia (English Spinach) roots on ferric nitrilotriacetate (Fe-NTA) induced hepatic oxidative stress and tumor promotion response

2007 ◽  
Vol 45 (10) ◽  
pp. 1821-1829 ◽  
Author(s):  
Irshad A. Lone ◽  
Gurpreet Kaur ◽  
Mohammad Athar ◽  
M. Sarwar Alam
Author(s):  
Takashi Hashimoto ◽  
Maki Kiyota ◽  
Kazuki Kanazawa

Boysenberry (Rubus loganbaccus × baileyanus Britt.) is one of the popular berries in Western countries. In the present study, the effect of the boysenberry juice on ferric nitrilotriacetate (Fe-NTA)-induced renal injury was investigated. ICR mice (7 weeks old, male) were ad libitum administered boysenberry juice for 1 week, and were intraperitoneally injected Fe-NTA (5 mg Fe/kg body weight) as an oxidant to renal. The consumption of boysenberry juice suppressed the Fe-NTA-increased thiobarbituric acid reactive substances (TBARS) in kidney and blood urea nitrogen (BUN). These results indicate that the consumption of boysenberry juice reduces the risk of oxidative stress.


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