Evaluation of chemopreventive and cytotoxic effect of lemon seed extracts on human breast cancer (MCF-7) cells

2012 ◽  
Vol 50 (2) ◽  
pp. 423-430 ◽  
Author(s):  
Jinhee Kim ◽  
Guddadarangavvanahally K. Jayaprakasha ◽  
Ram M. Uckoo ◽  
Bhimanagouda S. Patil
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Cytotoxic Effect ◽  
Human Breast ◽  
Seed Extracts ◽  
Mcf 7

scholarly journals Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468

2018 ◽  
Vol Volume 11 ◽  
pp. 7669-7677 ◽  
Author(s):  
Maryam Hamzeloo-Moghadam ◽  
Mahmoud Aghaei ◽  
Mohammad Hossein Abdolmohammadi ◽  
Amir Khalaj ◽  
Faranak Fallahian
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Cytotoxic Effect ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Apoptotic Signaling ◽  
Mcf 7

scholarly journals Synthesis and assessment of the cytotoxic effect of some of 1,4-dihydropyridine derivatives which contain azole moiety

2021 ◽  
pp. 64-64
Author(s):  
Saeed Ghoorbannejad ◽  
Dilmaghani Akbari ◽  
Abbas Nikoo
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Cytotoxic Effect ◽  
Ring System ◽  
Cytotoxic Agents ◽  
Human Breast ◽  
Cytotoxic Potential ◽  
Ft Ir ◽  
Dihydropyridine Derivatives ◽  
Mcf 7

A number of 1,4-dihydropyridine derivatives (9a-d, 10a-d, and 11a-d) were designed and synthesized by the reaction of 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones to 2,6-dibromomethyl-3,5-diethoxycarbonyl-4-(3-ni-trophenyl)-1,4-dihydropyridine. The synthesized compounds were characterrized using FT-IR, 1H-NMR, 13C-NMR spectral data, ESI-MS, and elemental analysis. The cytotoxicity of the synthesized compounds was evaluated in human breast cancer (MCF-7) cells based on the results of MTT assay. The results indicated that compound Diethyl 4-(3-nitrophenyl)-2,6-bis[((5-(3-nitrophenyl)-1,3,4-oxa-diazol-2-yl)thio)methyl]-1,4-dihydro pyridine-3,5-dicarboxylate (9b) with (IC50 = 23 ? 2.32 ?M) was the most potent derivative against MCF-7 cells. Based on the results, the use of oxadiazole moiety in the C2 and C6 positions of 1,4-di-hydropyridine ring system enhanced the cytotoxic potential of these derivatives. Therefore, some of the oxadiazole-substituted 1,4-DHPs may facilitate further modifications which result in the discovery of potent cytotoxic agents.

scholarly journals Synergistic cytotoxic effect of genistein and doxorubicin on drug-resistant human breast cancer MCF-7/Adr cells

2014 ◽  
Vol 32 (4) ◽  
pp. 1647-1653 ◽  
Author(s):  
JIA-PENG XUE ◽  
GENG WANG ◽  
ZONG-BIN ZHAO ◽  
QUN WANG ◽  
YUN SHI
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Cytotoxic Effect ◽  
Drug Resistant ◽  
Human Breast ◽  
Synergistic Cytotoxic Effect ◽  
Mcf 7

scholarly journals Anticancer Activity of Petroselinum sativum Seed Extracts on MCF-7 Human Breast Cancer Cells

2013 ◽  
Vol 14 (10) ◽  
pp. 5719-5723 ◽  
Author(s):  
Nida Nayyar Farshori ◽  
Ebtesam Saad Al-Sheddi ◽  
Mai Mohammad Al-Oqail ◽  
Javed Musarrat ◽  
Abdulaziz Ali Al-Khedhairy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Seed Extracts ◽  
Mcf 7

scholarly journals Cytotoxic effect of methanolic fractions of Scrophularia oxysepala on MCF-7 human breast cancer cell line

2013 ◽  
Vol 4 ◽  
Author(s):  
Orangi Mona ◽  
Baradaran Behzad ◽  
Pasdaran Ardalan ◽  
Kazemi Tohid ◽  
Hosseini Behnaz Sadat ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Human Breast Cancer ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Human Breast Cancer Cell ◽  
Human Breast ◽  
Mcf 7
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