Comparison of the Luteal Phase after Pituitary Suppression With GnRH-Agonist Versus GnRH Antagonist in Controlled Ovarian Hyperstimulation

2005 ◽  
Vol 84 ◽  
pp. S308 ◽  
Author(s):  
S.P. Willman ◽  
H.J. Kliman
Keyword(s):  
Gnrh Agonist ◽  
Luteal Phase ◽  
Gnrh Antagonist ◽  
Controlled Ovarian Hyperstimulation ◽  
Ovarian Hyperstimulation ◽  
Pituitary Suppression

scholarly journals Comparison of GnRH Agonist, GnRH Antagonist, and GnRH Antagonist Mild Protocol of Controlled Ovarian Hyperstimulation in Good Prognosis Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Martin Stimpfel ◽  
Eda Vrtacnik-Bokal ◽  
Barbara Pozlep ◽  
Irma Virant-Klun
Keyword(s):  
Gnrh Agonist ◽  
Birth Rate ◽  
Gnrh Antagonist ◽  
Live Birth Rate ◽  
Oocyte Retrieval ◽  
Controlled Ovarian Hyperstimulation ◽  
Good Prognosis ◽  
Ovarian Hyperstimulation ◽  
Embryo Freezing ◽  
Ectopic Pregnancies

The reports on how to stimulate the ovaries for oocyte retrieval in good prognosis patients are contradictory and often favor one type of controlled ovarian hyperstimulation (COH). For this reason, we retrospectively analyzed data from IVF/ICSI cycles carried out at our IVF Unit in good prognosis patients (aged <38 years, first and second attempts of IVF/ICSI, more than 3 oocytes retrieved) to elucidate which type of COH is optimal at our condition. The included patients were undergoing COH using GnRH agonist, GnRH antagonist or GnRH antagonist mild protocol in combination with gonadotrophins. We found significant differences in the average number of retrieved oocytes, immature oocytes, fertilized oocytes, embryos, transferred embryos, embryos frozen per cycle, and cycles with embryo freezing between studied COH protocols. Although there were no differences in live birth rate (LBR), miscarriages, and ectopic pregnancies between compared protocols, pregnancy rate was significantly higher in GnRH antagonist mild protocol in comparison with both GnRH antagonist and GnRH agonist protocols and cumulative LBR per cycle was significantly higher in GnRH antagonist mild protocol in comparison to GnRH agonist protocol. Our data show that GnRH antagonist mild protocol of COH could be the best method of choice in good prognosis patients.

scholarly journals Role of different GnRH agonist regimens in pituitary suppression and the outcome of controlled ovarian hyperstimulation

1996 ◽  
Vol 11 (suppl 3) ◽  
pp. 123-132 ◽  
Author(s):  
M. Filicori ◽  
G.E. Cognigni ◽  
R. Arnone ◽  
F. Carbone ◽  
A. Falbo ◽  
...  
Keyword(s):  
Gnrh Agonist ◽  
Controlled Ovarian Hyperstimulation ◽  
Ovarian Hyperstimulation ◽  
Pituitary Suppression
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