Successful pregnancy and delivery of two sets of monozygotic twins after intracytoplasmic sperm injection and embryo transfer: case report and literature review

2009 ◽  
Vol 92 (1) ◽  
pp. 392.e5-392.e8 ◽  
Author(s):  
Ozren Grgic ◽  
Marina Ivanisevic ◽  
Josip Djelmis ◽  
Drazen Lucinger ◽  
Lana Krile
2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Zakwan Khrait

Abstract Background Uterus didelphys results from a failure in Mullerian duct fusion and may be associated with complete or partial vaginal septa. Most cases of uterus didelphys are discovered incidentally during the workup of infertility or recurrent miscarriage. The incidence of uterus didelphys has been reported to be 0.2% in the infertile population. Case presentation A 35-year-old white Arab woman, gravida 0, parity 0, with a history of primary infertility of 8 years (a well-known male factor) presented to our infertility center. She was diagnosed as having uterus didelphys with severe male factor. The patient had three previous failed in vitro fertilization/intracytoplasmic sperm injection cycles outside our center. This is a case report of an infertile woman with uterus didelphys who conceived twice following single embryo transfer in both uterine horns successively. After the first successful pregnancy in the left uterine horn, the initial decision was to transfer the embryo to the same horn (left) because of the previous successful transfer. The very deep and long vagina forced us to reach one of the cervices, in which the embryo was placed in the right uterine horn, followed by the second successful pregnancy in the other, smaller horn. The patient gave her informed consent, both verbal and written, to use her information and images for medical publication. Conclusion Pregnancy is possible in women with uterus didelphys using single embryo transfer in in vitro fertilization/intracytoplasmic sperm injection cycles. It is recommended that both horns be given a chance.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi Zhang ◽  
Cheng Chen ◽  
Min Lin ◽  
Kan Deng ◽  
Huijuan Zhu ◽  
...  

Abstract Background Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. Case presentation A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020. Conclusions Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded.


Author(s):  
Satoshi Hosoya ◽  
Yuta Kasahara ◽  
Hiromi Komazaki ◽  
Hiroshi Kishi ◽  
Hirokuni Takano ◽  
...  

2000 ◽  
Vol 73 (5) ◽  
pp. 1057-1058 ◽  
Author(s):  
Nobuhiko Suganuma ◽  
Madoka Furuhashi ◽  
Tomoko Ando ◽  
Yoshimasa Asada ◽  
Osamu Mori ◽  
...  

2020 ◽  
Author(s):  
Caixia Liu ◽  
Dong Han ◽  
Jianguo Chen ◽  
Ying Liu ◽  
Dong Li ◽  
...  

Abstract Although some zero pronuclei (0PN) zygotes cleave and develop into good embryos, they are usually discarded because they lack two distinct pronuclei (2PN). In this case report, we followed four couples to determine whether 0PN embryo could be used in late rescue intracytoplasmic sperm injection (L-R-ICSI). Here we report five healthy infants, including one set of twins, derived from "0PN" embryos from four frozen–warmed embryo transfer (FET) cycles in L-R-ICSI between 2015 and 2017. Of nine infants born from L-R-ICSI cycles in our center, five were "0PN" embryos, and all remain healthy. Embryos from "0PNs" such as 2PN can develop into healthy babies using L-R-ICSI. This finding suggests that embryos from "0PNs" in L-R-ICSI may be different from traditional 0PN gametes and more likely to originate from 2PN gametes and they may be used in those infertile couples who lack 2PN embryos, instead of discarding them. The use of "0PN" embryos increases the cycles reaching embryo transfer, allowing some infertile couples to have healthy children and to avoid mental anguish and wasted time and money.


2020 ◽  
Vol 8 (11) ◽  
pp. 2217-2222
Author(s):  
Chayada Tangshewinsirikul ◽  
Wirada Dulyaphat ◽  
Sanpon Diawtipsukon ◽  
Yada Tingthanatikul ◽  
Chonthicha Satirapod ◽  
...  

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