Current status of systems biology in Aspergilli

2009 ◽  
Vol 46 (1) ◽  
pp. S180-S190 ◽  
Author(s):  
M.R. Andersen ◽  
J. Nielsen
Keyword(s):  
Systems Biology ◽  
Current Status

scholarly journals Systems biology: current status and challenges

2020 ◽  
Vol 77 (3) ◽  
pp. 379-380
Author(s):  
Anze Zupanic ◽  
Hans C. Bernstein ◽  
Ines Heiland
Keyword(s):  
Systems Biology ◽  
Current Status

scholarly journals Current Status and Future Strategies to Increase Secondary Metabolite Production from Cyanobacteria

2020 ◽  
Vol 8 (12) ◽  
pp. 1849
Author(s):  
Yujin Jeong ◽  
Sang-Hyeok Cho ◽  
Hookeun Lee ◽  
Hyung-Kyoon Choi ◽  
Dong-Myung Kim ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Systems Biology ◽  
Secondary Metabolites ◽  
Regulatory Networks ◽  
Carbon Fixation ◽  
Industrial Applications ◽  
Current Status ◽  
Enhanced Production ◽  
Biochemical Production ◽  
Genome Scale

Cyanobacteria, given their ability to produce various secondary metabolites utilizing solar energy and carbon dioxide, are a potential platform for sustainable production of biochemicals. Until now, conventional metabolic engineering approaches have been applied to various cyanobacterial species for enhanced production of industrially valued compounds, including secondary metabolites and non-natural biochemicals. However, the shortage of understanding of cyanobacterial metabolic and regulatory networks for atmospheric carbon fixation to biochemical production and the lack of available engineering tools limit the potential of cyanobacteria for industrial applications. Recently, to overcome the limitations, synthetic biology tools and systems biology approaches such as genome-scale modeling based on diverse omics data have been applied to cyanobacteria. This review covers the synthetic and systems biology approaches for advanced metabolic engineering of cyanobacteria.

scholarly journals Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites

2016 ◽  
Vol 33 (8) ◽  
pp. 933-941 ◽  
Author(s):  
Hyun Uk Kim ◽  
Pep Charusanti ◽  
Sang Yup Lee ◽  
Tilmann Weber
Keyword(s):  
Metabolic Engineering ◽  
Systems Biology ◽  
Secondary Metabolites ◽  
Current Status ◽  
Optimal Production

This Highlight examines current status of metabolic engineering and systems biology tools deployed for the optimal production of prokaryotic secondary metabolites.

The Systems Biology Graphical Notation: Current Status and Applications in Systems Medicine

2021 ◽  
pp. 372-381 ◽  
Author(s):  
Vasundra Touré ◽  
Andreas Dräger ◽  
Augustin Luna ◽  
Ugur Dogrusoz ◽  
Adrien Rougny
Keyword(s):  
Systems Biology ◽  
Current Status ◽  
Systems Medicine ◽  
Graphical Notation

A systems approach to understanding root development

2006 ◽  
Vol 84 (5) ◽  
pp. 695-701 ◽  
Author(s):  
Siobhan M. Brady ◽  
Philip N. Benfey
Keyword(s):  
Systems Biology ◽  
Systems Theory ◽  
Root Development ◽  
Evolutionary Biology ◽  
Systems Approach ◽  
Process Analysis ◽  
Model Organisms ◽  
Current Status ◽  
Data Sets ◽  
Component Identification

Systems theory has been applied to process analysis in a variety of scientific disciplines from engineering to evolutionary biology. In the recent postgenomic era, the accumulation of an enormous amount of data gained from a variety of technologies has led to a revisiting of systems theory concepts. This systems biology approach has been integral in understanding a variety of processes in a number of model organisms. This review gives an overview of systems biology approaches, from component identification to modeling of networks. Various features of the root, including its development and the availability of high resolution gene expression data sets that describe root development, make the root amenable to a systems approach. The current status of systems approaches to understanding root development is reviewed.

Current status of special planetary and lunar theories and ephemerides

1966 ◽  
Vol 25 ◽  
pp. 266-267
Author(s):  
R. L. Duncombe
Keyword(s):  
Observational Data ◽  
Current Status ◽  
Numerical Errors

An examination of some specialized lunar and planetary ephemerides has revealed inconsistencies in the adopted planetary masses, the presence of non-gravitational terms, and some outright numerical errors. They should be considered of temporary usefulness only, subject to subsequent amendment as required for the interpretation of observational data.

Combining integrated systems-biology approaches with intervention-based experimental design provides a higher-resolution path forward for microbiome research

2019 ◽  
Vol 42 ◽  
Author(s):  
J. Alfredo Blakeley-Ruiz ◽  
Carlee S. McClintock ◽  
Ralph Lydic ◽  
Helen A. Baghdoyan ◽  
James J. Choo ◽  
...  
Keyword(s):  
Systems Biology ◽  
High Resolution ◽  
Experimental Design ◽  
Integrated Systems ◽  
Microbiome Research ◽  
Constructive Criticism

Abstract The Hooks et al. review of microbiota-gut-brain (MGB) literature provides a constructive criticism of the general approaches encompassing MGB research. This commentary extends their review by: (a) highlighting capabilities of advanced systems-biology “-omics” techniques for microbiome research and (b) recommending that combining these high-resolution techniques with intervention-based experimental design may be the path forward for future MGB research.

Current Status of Solid-State X-Ray Systems

1985 ◽  
Vol 43 ◽  
pp. 158-161
Author(s):  
Martin Peckerar ◽  
Anastasios Tousimis
Keyword(s):  
Solid State ◽  
Electric Fields ◽  
Spectral Lines ◽  
Current Status ◽  
Mobile Charge ◽  
Electron Hole ◽  
X Ray ◽  
Sensing Systems ◽  
Transmission Electron ◽  
Electron Microscopes

Solid state x-ray sensing systems have been used for many years in conjunction with scanning and transmission electron microscopes. Such systems conveniently provide users with elemental area maps and quantitative chemical analyses of samples. Improvements on these tools are currently sought in the following areas: sensitivity at longer and shorter x-ray wavelengths and minimization of noise-broadening of spectral lines. In this paper, we review basic limitations and recent advances in each of these areas. Throughout the review, we emphasize the systems nature of the problem. That is. limitations exist not only in the sensor elements but also in the preamplifier/amplifier chain and in the interfaces between these components.Solid state x-ray sensors usually function by way of incident photons creating electron-hole pairs in semiconductor material. This radiation-produced mobile charge is swept into external circuitry by electric fields in the semiconductor bulk.

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