Interplay between calcineurin and the Slt2 MAP-kinase in mediating cell wall integrity, conidiation and virulence in the insect fungal pathogen Beauveria bassiana

2015 ◽  
Vol 83 ◽  
pp. 78-91 ◽  
Author(s):  
Shuaishuai Huang ◽  
Zhangjiang He ◽  
Shiwei Zhang ◽  
Nemat O. Keyhani ◽  
Yulin Song ◽  
...  
Keyword(s):  
Cell Wall ◽  
Map Kinase ◽  
Beauveria Bassiana ◽  
Fungal Pathogen ◽  
Cell Wall Integrity

The MAP kinase Bbslt2 controls growth, conidiation, cell wall integrity, and virulence in the insect pathogenic fungus Beauveria bassiana

2012 ◽  
Vol 49 (7) ◽  
pp. 544-555 ◽  
Author(s):  
Xingdan Luo ◽  
Nemat O. Keyhani ◽  
Xiaodong Yu ◽  
Zhangjiang He ◽  
Zhibing Luo ◽  
...  
Keyword(s):  
Cell Wall ◽  
Map Kinase ◽  
Beauveria Bassiana ◽  
Pathogenic Fungus ◽  
Cell Wall Integrity ◽  
Fungus Beauveria Bassiana

scholarly journals The Cek1 and Hog1 Mitogen-Activated Protein Kinases Play Complementary Roles in Cell Wall Biogenesis and Chlamydospore Formation in the Fungal Pathogen Candida albicans

2006 ◽  
Vol 5 (2) ◽  
pp. 347-358 ◽  
Author(s):  
B. Eisman ◽  
R. Alonso-Monge ◽  
E. Román ◽  
D. Arana ◽  
C. Nombela ◽  
...  
Keyword(s):  
Cell Wall ◽  
Candida Albicans ◽  
Map Kinase ◽  
Fungal Pathogen ◽  
Hog Pathway ◽  
Cell Wall Biogenesis ◽  
Chlamydospore Formation ◽  
Mitogen Activated Protein ◽  
Morphological Transitions ◽  
Relationship Of

ABSTRACT The Hog1 mitogen-activated protein (MAP) kinase mediates an adaptive response to both osmotic and oxidative stress in the fungal pathogen Candida albicans. This protein also participates in two distinct morphogenetic processes, namely the yeast-to-hypha transition (as a repressor) and chlamydospore formation (as an inducer). We show here that repression of filamentous growth occurs both under serum limitation and under other partially inducing conditions, such as low temperature, low pH, or nitrogen starvation. To understand the relationship of the HOG pathway to other MAP kinase cascades that also play a role in morphological transitions, we have constructed and characterized a set of double mutants in which we deleted both the HOG1 gene and other signaling elements (the CST20, CLA4, and HST7 kinases, the CPH1 and EFG1 transcription factors, and the CPP1 protein phosphatase). We also show that Hog1 prevents the yeast-to-hypha switch independent of all the elements analyzed and that the inability of the hog1 mutants to form chlamydospores is suppressed when additional elements of the CEK1 pathway (CST20 or HST7) are altered. Finally, we report that Hog1 represses the activation of the Cek1 MAP kinase under basal conditions and that Cek1 activation correlates with resistance to certain cell wall inhibitors (such as Congo red), demonstrating a role for this pathway in cell wall biogenesis.

Pim1, a MAP kinase involved in cell wall integrity in Pichia pastoris

2001 ◽  
Vol 265 (4) ◽  
pp. 604-614 ◽  
Author(s):  
I.C. Cosano ◽  
H. Martín ◽  
M. Flández ◽  
C. Nombela ◽  
M. Molina
Keyword(s):  
Cell Wall ◽  
Pichia Pastoris ◽  
Map Kinase ◽  
Cell Wall Integrity

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus

2009 ◽  
Vol 46 (12) ◽  
pp. 909-918 ◽  
Author(s):  
Vito Valiante ◽  
Radhika Jain ◽  
Thorsten Heinekamp ◽  
Axel A. Brakhage
Keyword(s):  
Cell Wall ◽  
Aspergillus Fumigatus ◽  
Map Kinase ◽  
Cell Wall Integrity

scholarly journals Geranylgeranyltransferase Cwg2-Rho4/Rho5 module is implicated in the Pmk1 MAP kinase-mediated cell wall integrity pathway in fission yeast

2015 ◽  
Vol 20 (4) ◽  
pp. 310-323 ◽  
Author(s):  
Akira Doi ◽  
Ayako Kita ◽  
Yuki Kanda ◽  
Takaya Uno ◽  
Keita Asami ◽  
...  
Keyword(s):  
Cell Wall ◽  
Map Kinase ◽  
Fission Yeast ◽  
Cell Wall Integrity ◽  
Cell Wall Integrity Pathway

scholarly journals PRO40 Is a Scaffold Protein of the Cell Wall Integrity Pathway, Linking the MAP Kinase Module to the Upstream Activator Protein Kinase C

PLoS Genetics ◽  
2014 ◽  
Vol 10 (9) ◽  
pp. e1004582 ◽  
Author(s):  
Ines Teichert ◽  
Eva Katharina Steffens ◽  
Nicole Schnaß ◽  
Benjamin Fränzel ◽  
Christoph Krisp ◽  
...  
Keyword(s):  
Cell Wall ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Map Kinase ◽  
Scaffold Protein ◽  
Cell Wall Integrity ◽  
Activator Protein ◽  
Kinase C ◽  
Cell Wall Integrity Pathway
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