Determination of velocity and angular displacement of bubbly flows by means of wire-mesh sensors and correlation analysis

Linezolid can cause serious haematological toxicity, such as thrombocytopenia and aneamia. Heme, composed of iron and porphyrin, is an important component of hemoglobin. In order to investigate the relationship between the concentration of linezolid and heme in the plasma of infected patients, a UPLC-MS/MS method that can determine the concentrations of linezolid and heme simultaneously was developed and validated. A total of 96 healthy subjects and 81 infected patients, who received blood routine blood tests, were included and determined by the UPLC-MS/MS method. The results showed that the concentration of linezolid was 5.08 ± 3.46 μ g / mL in infected patients who were treated with linezolid. The heme in healthy subjects was 7.05 ± 8.68 μ g / mL , and it was significantly decreased to 0.88 ± 0.79 μ g / mL in infected patients ( P < 0.01 ). Spearman correlation analysis showed that linezolid had a high negative correlation with platelet (PLT) ( R = − 0.309 ). Heme had a high positive correlation with hemoglobin (Hb) ( R = 0.249 ) in healthy subjects and infected patients. The ROC analysis showed that heme had diagnostic value to distinguish low Hb (110 g/L). In conclusion, there was a positive correlation between heme and Hb, and this correlation was also observed in infected patients. A high concentration of linezolid was inclined to decrease PLT. Monitoring of heme and linezolid helps in the early diagnose of low Hb and PLT.

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First Determination of 2D Speed Distribution within the Bodies of Coronal Mass Ejections with Cross-correlation Analysis

The Astrophysical Journal ◽

10.3847/1538-4357/ab2713 ◽

2019 ◽

Vol 880 (1) ◽

pp. 41 ◽

Cited By ~ 4

Author(s):

Beili Ying ◽

Alessandro Bemporad ◽

Silvio Giordano ◽

Paolo Pagano ◽

Li Feng ◽

...

Keyword(s):

Correlation Analysis ◽

Coronal Mass Ejections ◽

Cross Correlation ◽

Speed Distribution ◽

Cross Correlation Analysis

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Determination of low-temperature crack control parameter of binding asphalt materials based on gray correlation analysis

Construction and Building Materials ◽

10.1016/j.conbuildmat.2019.05.065 ◽

2019 ◽

Vol 217 ◽

pp. 226-233 ◽

Cited By ~ 8

Author(s):

Chuanfeng Zheng ◽

Ruiming Li ◽

Mingjun Hu ◽

Linlin Zou

Keyword(s):

Low Temperature ◽

Correlation Analysis ◽

Control Parameter ◽

Crack Control ◽

Asphalt Materials ◽

Gray Correlation ◽

Gray Correlation Analysis ◽

Temperature Crack

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Correlation analysis of fundus autofluorescence, spectral domain optical coherence tomography, and visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept

European Journal of Ophthalmology ◽

10.1177/1120672119833267 ◽

2019 ◽

Vol 29 (3) ◽

pp. 271-277 ◽

Cited By ~ 4

Author(s):

Sergio E Hernandez-Da Mota ◽

Enrique A Roig Melo-Granados ◽

Jans Fromow-Guerra ◽

Francisco Bejar-Cornejo ◽

Roberto Gallego-Pinazo ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Regression Analysis ◽

Correlation Analysis ◽

Visual Function ◽

Macular Oedema ◽

Fundus Autofluorescence ◽

Diabetic Macular Oedema ◽

Optical Coherence ◽

Average Thickness

Purpose: The aim of this study was to evaluate the correlations between fundus autofluorescence and morphologic parameters as well as visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept. Methods: A total of 34 eyes of 20 patients with untreated diabetic macular oedema received an intravitreal injection of ziv-aflibercept at baseline, and 1 and 2 months later. The baseline, 1-month, and two-month best corrected visual acuity determination, contrast sensitivity, spectral domain optical coherence tomography, mean central macular thickness, mean macular cube volume, mean macular cube average thickness, and fundus autofluorescence (decreased, normal, or increased; and single or multiple spots) were measured. Correlation analysis with a determination of Spearman’s rank correlation coefficient, regression analysis, agreement between investigators, and Friedman’s test were used for statistical analyses. Results: A direct correlation was observed between baseline fundus autofluorescence and macular cube average thickness at 1 month (r = 0.51, p = 0.020) and between fundus autofluorescence at 1 month and baseline macular cube average thickness (r = 0.50, p = 0.021). Regression analysis showed a coefficient of determination of 0.29 (p = 0.016) between baseline fundus autofluorescence and macular cube average thickness at 1 month. Conclusion: In patients with diabetic macular oedema, the pretreatment baseline degree of foveal fundus autofluorescence might be helpful in predicting macular cube average thickness in patients undergoing treatment with intravitreal ziv-aflibercept in the short term.

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