An integrated manufacturing strategy to fabricate delivery system using gelatin/alginate hybrid hydrogels: 3D printing and freeze-drying

2021 ◽  
Vol 111 ◽  
pp. 106262
Author(s):  
Chih-Chun Kuo ◽  
Hantang Qin ◽  
Yiliang Cheng ◽  
Xuepeng Jiang ◽  
Xiaolei Shi
LWT ◽  
2022 ◽  
pp. 113075
Author(s):  
Chih-Chun Kuo ◽  
Stephanie Clark ◽  
Hantang Qin ◽  
Xiaolei Shi

2020 ◽  
Vol 46 (4) ◽  
pp. 531-538 ◽  
Author(s):  
Ting-Ting Yan ◽  
Zhu-Fen Lv ◽  
Pan Tian ◽  
Min-Mei Lin ◽  
Wei Lin ◽  
...  

2019 ◽  
Vol 7 (17) ◽  
pp. 2855-2864 ◽  
Author(s):  
Wenyang Pan ◽  
Thomas J. Wallin ◽  
Jérémy Odent ◽  
Mighten C. Yip ◽  
Bobak Mosadegh ◽  
...  

This paper reports the rapid 3D printing of tough (toughness, UT, up to 141.6 kJ m−3), highly solvated (ϕwater ∼ 60 v/o), and antifouling hybrid hydrogels for potential uses in biomedical, smart materials, and sensor applications, using a zwitterionic photochemistry compatible with stereolithography (SLA).


2019 ◽  
Vol 9 (4-s) ◽  
pp. 861-866 ◽  
Author(s):  
Lalita Devi ◽  
Punam Gaba ◽  
Hitesh Chopra

Hydrogels possess three-dimensional polymeric network structure and equipped for retaining extensive measure of water or organic fluids. This quality makes them as exceptional candidate for the simulation of extra cellular matrixes. For this the three dimensional printing (3DP) has evolved as the technique for the formation of the digital models. The 3DP is capable for processing the prescriptions and the therapeutic gadgets. One of the technique known as stereolithographic (SLA) printing has shown promising results in formulating the hydrogel based system for fabrication. The SLA acts by cross connecting the saps to shape the polymer matrices. Due to water captured in the gels it is conceivable to create the pre- wetted, medicate hydrogels and gadgets. The 3DP helps in formation of tailor made drug delivery system as per needs of patients. Many of Bioinks has been tried up for the hydrogel formation such as collagen, gelatin, hyaluronan, silk, alginate, and nanocellulose etc. Keywords: 3D Printing, Hydrogel, Steriolithography


2019 ◽  
Vol 24 (42) ◽  
pp. 5029-5038 ◽  
Author(s):  
Md. Shoaib Alam ◽  
Ayesha Akhtar ◽  
Iftikhar Ahsan ◽  
Sheikh Shafiq-un-Nabi

Background: 3D printed pharmaceutical products are revolutionizing the pharmaceutical industry as a prospective mean to achieve a personalized method of treatments acquired to the specially designed need of each patient. It will depend upon age, weight, concomitants, pharmacogenetics and pharmacokinetic profile of the patient and thus transforming the current pharmaceutical market as a potential alternative to conventional medicine. 3D printing technology is getting more consideration in new medicine formulation development as a modern and better alternative to control many challenges associated with conventional medicinal products. There are many advantages of 3D printed medicines which create tremendous opportunities for improving the acceptance, accuracy and effectiveness of these medicines. In 2015, United State Food and Drug Administration has approved the first 3D printed tablet (Spritam®) and had shown the emerging importance of this technology. Methods: This review article summarizes as how in-depth knowledge of drugs and their manufacturing processes can assist to manage different strategies for various 3D printing methods. The principal goal of this review is to provide a brief introduction about the present techniques employed in tech -medicine evolution from conventional to a novel drug delivery system. Results: It is evidenced that through its unparalleled advantages of high-throughput, versatility, automation, precise spatial control and fabrication of hierarchical structures, the implementation of 3D printing for the expansion and delivery of controlled drugs acts as a pivotal role. Conclusion: 3D printing technology has an extraordinary ability to provide elasticity in the manufacturing and designing of composite products that can be utilized in programmable and personalized medicine. Personalized medicine helps in improving drug safety and minimizes side effects such as toxicity to individual human being which is associated with unsuitable drug dose.


2022 ◽  
Vol 275 ◽  
pp. 125302
Author(s):  
Xiaobiao Du ◽  
Mohammad Dehghani ◽  
Naif Alsaadi ◽  
Mazyar Ghadiri Nejad ◽  
Saeed Saber-Samandari ◽  
...  

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