Emergence of new psychoactive substance 2-fluorodeschloroketamine: Toxicology and urinary analysis in a cluster of patients exposed to ketamine and multiple analogues

Objective: To explore the associations of characteristics of the cluster environment with new psychoactive substances (NPS) use in Thailand. Materials and Methods: A cross-sectional study was done on 30,411 Thai people, stratified in multi-stage cluster sampling. Trained interviewers conducted a semi-structured interview in 2016. A multilevel binary logistic regression model was employed to estimate the effects of the cluster environment on the NPS use. Results: NPS was widely used. The past month prevalence was 13.6%, and habitual use was 4.4%. Clustering significantly affects the spread of NPS use. Controlling for cluster effects, a likelihood of current NPS use was associated with elementary education, occupation, and reported health problems. While a higher likelihood of habitual NPS use was associated with elementary education, employed, and perceived mental health problem. Conclusion: NPS use was influenced by characteristics of the cluster environment. Therefore, demand reduction strategies should be designed based on a consideration of the impact of cluster context on NPS use behaviors. Keywords: Cluster effect, New psychoactive substance, NPS, Thailand

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Gamma-Butyrolactone Overdose Potentially Complicated by Co-Ingestion of Industrial Solvent N-Methyl-2-Pyrrolidone

Journal of Analytical Toxicology ◽

10.1093/jat/bkaa076 ◽

2020 ◽

Author(s):

Jonathan Melamed ◽

Roy Gerona ◽

Paul D Blanc ◽

Paul Takamoto ◽

Stephanie Conner ◽

...

Keyword(s):

Substance Use ◽

Psychoactive Substance ◽

New Psychoactive Substance ◽

Use Patterns ◽

Endogenous Metabolism ◽

Gamma Hydroxybutyrate ◽

Other Substances ◽

History Of ◽

Psychoactive Substance Use ◽

Gamma Butyrolactone

Abstract Gamma-hydroxybutyrate (GHB) is misused as an intoxicant, either alone or concurrently with other substances. Because GHB is illegal, the precursor chemicals 1,4-butanediol and gamma-butyrolactone are also misused for the same effect, either through pre-ingestion alteration or endogenous metabolism to GHB. We describe a case of a 50-year-old man with a history of polysubstance misuse who experienced an overdose of GHB from gamma-butyrolactone ingestion. The patient also co-ingested a common industrial solvent, N-methyl-2-pyrrolidone (NMP). This co-ingested substance raised theoretical concern of metabolism to a GHB congener, underscoring that the emergence of new psychoactive substance use patterns requires ongoing vigilance and toxicologic confirmation.

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Determination of the new psychoactive substance dichloropane in saliva by microextraction by packed sorbent – Ion mobility spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2019.06.054 ◽

2019 ◽

Vol 1603 ◽

pp. 61-66 ◽

Cited By ~ 9

Author(s):

Aitor Sorribes-Soriano ◽

Amparo Monedero ◽

Francesc A. Esteve-Turrillas ◽

Sergio Armenta

Keyword(s):

Ion Mobility Spectrometry ◽

Ion Mobility ◽

Psychoactive Substance ◽

New Psychoactive Substance ◽

Microextraction By Packed Sorbent ◽

Packed Sorbent

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Determining changes in new psychoactive substance use in Australia by wastewater analysis

The Science of The Total Environment ◽

10.1016/j.scitotenv.2020.139209 ◽

2020 ◽

Vol 731 ◽

pp. 139209 ◽

Cited By ~ 3

Author(s):

Richard Bade ◽

Jason M. White ◽

Lynn Nguyen ◽

Benjamin J. Tscharke ◽

Jochen F. Mueller ◽

...

Keyword(s):

Substance Use ◽

Wastewater Analysis ◽

Psychoactive Substance ◽

New Psychoactive Substance ◽

Psychoactive Substance Use

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Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho - and meta - positional isomers

Drug Testing and Analysis ◽

10.1002/dta.2396 ◽

2018 ◽

Vol 10 (9) ◽

pp. 1404-1416 ◽

Cited By ~ 3

Author(s):

Gavin McLaughlin ◽

Michael H. Baumann ◽

Pierce V. Kavanagh ◽

Noreen Morris ◽

John D. Power ◽

...

Keyword(s):

Positional Isomers ◽

Psychoactive Substance ◽

New Psychoactive Substance ◽

Monoamine Transporter ◽

Analytical Characterization

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Identification of a new psychoactive substance in seized material: the synthetic opioidN-phenyl-N-[1-(2-phenethyl)piperidin-4-yl]prop-2-enamide (Acrylfentanyl)

Drug Testing and Analysis ◽

10.1002/dta.2046 ◽

2016 ◽

Vol 9 (3) ◽

pp. 415-422 ◽

Cited By ~ 39

Author(s):

Torben Breindahl ◽

Andreas Kimergård ◽

Mette Findal Andreasen ◽

Daniel Sejer Pedersen

Keyword(s):

Psychoactive Substance ◽

New Psychoactive Substance

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NEW PSYCHOACTIVE SUBSTANCES AS A CRIME OBJECT

INDIVIDUAL. SOCIETY. STATE. Proceedings of the International Student and Teacher Scientific and Practical Conference ◽

10.17770/iss2017.3007 ◽

2017 ◽

pp. 258

Author(s):

Arnis Slesars ◽

Aija Jermacāne

Keyword(s):

Public Health ◽

United Nations ◽

Criminal Liability ◽

New Psychoactive Substances ◽

Psychoactive Substance ◽

Psychoactive Substances ◽

New Psychoactive Substance ◽

Advantages And Disadvantages ◽

Public Health Threat ◽

History Of

A new psychoactive substance is defined as a new narcotic or psychotropic drug, in pure form or in preparation, that is not controlled by the United Nations drug conventions (1961, 1971), but which may pose a public health threat comparable to that posed by substances listed in these conventions. The author researched and analyzed: 1.History of new psychoactive substances in Latvia; 2.Legislative approaches for restricting new psychoactive substances in Latvia; 3.Advantages and disadvantages of criminal liability against new psychoactive substances in Latvia.

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