Japanese rice wine (Sake)-derived pyroglutamyl peptides have anti-inflammatory effect on dextran sulfate sodium (DSS)-induced acute colitis in mice

2018 ◽  
Vol 120 ◽  
pp. S141
Author(s):  
Sayori Wada ◽  
Tamami Kiyono ◽  
Shoko Fukunaga ◽  
Wataru Aoi ◽  
Yuji Naito ◽  
...  
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Rice Wine ◽  
Acute Colitis ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-Inflammatory Effect of Phytoncide in an Animal Model of Gastrointestinal Inflammation

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1895
Author(s):  
Azra Memon ◽  
Bae Yong Kim ◽  
Se-eun Kim ◽  
Yuliya Pyao ◽  
Yeong-Geun Lee ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Animal Model ◽  
Gastric Ulcer ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Inos Expression ◽  
Gastrointestinal Inflammation ◽  
Anti Inflammatory ◽  
Oxide Synthase ◽  
Inflammatory Effect

Background: Phytoncide is known to have antimicrobial and anti-inflammatory properties. Purpose: This study was carried out to confirm the anti-inflammatory activity of two types of phytoncide extracts from pinecone waste. Methods: We made two types of animal models to evaluate the efficacy, an indomethacin-induced gastroenteritis rat model and a dextran sulfate sodium-induced colitis mouse model. Result: In the gastroenteritis experiment, the expression of induced-nitric oxide synthase (iNOS), a marker for inflammation, decreased in the phytoncide-supplemented groups, and gastric ulcer development was significantly inhibited (p < 0.05). In the colitis experiment, the shortening of the colon length and the iNOS expression were significantly suppressed in the phytoncide-supplemented group (p < 0.05). Conclusions: Through this study, we confirmed that phytoncide can directly inhibit inflammation in digestive organs. Although further research is needed, we conclude that phytoncide has potential anti-inflammatory properties in the digestive tract and can be developed as a functional agent.

Antioxidant and anti-inflammatory effect of plumieride in dextran sulfate sodium-induced colitis in mice

2018 ◽  
Vol 99 ◽  
pp. 697-703 ◽  
Author(s):  
Thaise Boeing ◽  
Priscila de Souza ◽  
Tiago José Bonomini ◽  
Luísa Nathália Bolda Mariano ◽  
Lincon Bordignon Somensi ◽  
...  
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Evaluation of the Anti-Inflammatory Effect of Baicalein on Dextran Sulfate Sodium-Induced Colitis in Mice

Planta Medica ◽  
2002 ◽  
Vol 68 (3) ◽  
pp. 268-271 ◽  
Author(s):  
Tie Hong ◽  
Guang-Bi Jin ◽  
Shigefumi Cho ◽  
Jong-Chol Cyong
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Carbon Monoxide Liberated from Carbon Monoxide-Releasing Molecule Exerts an Anti-inflammatory Effect on Dextran Sulfate Sodium-Induced Colitis in Mice

2010 ◽  
Vol 56 (6) ◽  
pp. 1663-1671 ◽  
Author(s):  
Tomohisa Takagi ◽  
Yuji Naito ◽  
Kazuhiko Uchiyama ◽  
Takahiro Suzuki ◽  
Ikuhiro Hirata ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Monocolonization of Germ-Free Mice withBacteroides fragilisProtects against Dextran Sulfate Sodium-Induced Acute Colitis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Chien-Chao Chiu ◽  
Yung-Hao Ching ◽  
Yu-Chih Wang ◽  
Ju-Yun Liu ◽  
Yen-Peng Li ◽  
...  
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Inflammatory Responses ◽  
Inflammatory Cells ◽  
Interleukin 10 ◽  
Myeloperoxidase Activity ◽  
Acute Colitis ◽  
Germ Free ◽  
Intestinal Immune System ◽  
Anti Inflammatory

Ulcerative colitis is inflammatory conditions of the colon caused by interplay of genetic and environmental factors. Previous studies indicated that the gut microflora may be involved in the colonic inflammation.Bacteroides fragilis(BF) is a Gram-negative anaerobe belonging to the colonic symbiotic. We aimed to investigate the protective role ofBFin a colitis model induced in germ-free (GF) mice by dextran sulfate sodium (DSS). GF C57BL/6JNarl mice were colonized withBFfor 28 days before acute colitis was induced by DSS.BFcolonization significantly increased animal survival by 40%, with less reduction in colon length, and decreased infiltration of inflammatory cells (macrophages and neutrophils) in colon mucosa following challenge with DSS. In addition,BFcould enhance the mRNA expression of anti-inflammatory-related cytokine such as interleukin 10 (IL-10) with polymorphism cytokineIL-17and diminish that of proinflammatory-related tumor necrosis factorαwith inducible nitric oxide synthase in the ulcerated colon. Myeloperoxidase activity was also decreased inBF-DSS mice. Taking these together, theBFcolonization significantly ameliorated DSS-induced colitis by suppressing the activity of inflammatory-related molecules and inducing the production of anti-inflammatory cytokines.BFmay play an important role in maintaining intestinal immune system homeostasis and regulate inflammatory responses.

scholarly journals Anti-inflammatory effect of Euphorbia supina extract in dextran sulfate sodium-induced colitis mice

2017 ◽  
Vol 81 (11) ◽  
pp. 2178-2185 ◽  
Author(s):  
Ji-Yun Cha ◽  
Yong-Deok Jeon ◽  
Mingjie Xin ◽  
Do-Kuk Kim ◽  
Hoon-Yeon Lee ◽  
...  
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Anti-inflammatory effect of fucoxanthin on dextran sulfate sodium-induced colitis in mice

2018 ◽  
Vol 34 (12) ◽  
pp. 1791-1795 ◽  
Author(s):  
Yuan-Ping Yang ◽  
Qiao-Yun Tong ◽  
Shi-Hua Zheng ◽  
Ming-Dong Zhou ◽  
You-Meng Zeng ◽  
...  
Keyword(s):  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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