Glyoxalase 2 correlates with redox signaling and enhances survival outcome in patients with hepatocellular carcinoma

2018 ◽  
Vol 128 ◽  
pp. S71
Author(s):  
Dinh-Truong Nguyen ◽  
Quynh Hoa Tran ◽  
Xuan The Hoang ◽  
Ngoc Huyen Vu ◽  
Kim Van Thi Le ◽  
...  
Medicine ◽  
2020 ◽  
Vol 99 (48) ◽  
pp. e23358
Author(s):  
Andrew K.Y. Fung ◽  
Nicole M.Y. Cheng ◽  
Charing C.N. Chong ◽  
Kit-Fai Lee ◽  
John Wong ◽  
...  

2019 ◽  
Vol 15 (24) ◽  
Author(s):  
Olusegun Adekanle ◽  
Oluwasegun Ijarotimi ◽  
Akinwumu Oluwole Komolafe ◽  
Samuel Anu Olowookere ◽  
Comfort Olusola Famurewa ◽  
...  

2018 ◽  
Vol 48 (5) ◽  
pp. 1882-1893 ◽  
Author(s):  
Mohammed Alnaggar ◽  
Mao Lin ◽  
Adnan Mesmar ◽  
Shuzhen Liang ◽  
Ammar Qaid ◽  
...  

Background/Aims: We evaluated the clinical effectiveness of irreversible electroporation (IRE) in combination with immunotherapy using allogenic natural killer cells (NK) for stage IV hepatocellular carcinoma (HCC). Methods: The study involved 40 patients with stage IV HCC who were divided equally into two groups: 1) simple IRE; and 2) IRE plus allogenic NK cells (IRE-NK); we mainly assessed the overall survival (OS). Results: The effect of the IRE-NK treatment was synergistic, i.e., not only did it enhance immune function, it also decreased alpha-fetoprotein expression and showed significantly good clinical effectiveness. At the median 7.6-month follow-up (range, 3.8–12.1 months), median OS was higher in the IRE-NK group (10.1 months) than in the IRE group (8.9 months, P = 0.0078). Conclusion: IRE combined with allogeneic NK cell immunotherapy significantly increases the median OS of patients with stage IV HCC.


2007 ◽  
Vol 12 (1) ◽  
pp. 183-191 ◽  
Author(s):  
Kelvin K. Ng ◽  
Ronnie T. Poon ◽  
Chung-Mau Lo ◽  
Jimmy Yuen ◽  
Wai Kuen Tso ◽  
...  

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