Sa1604 Comparison of a Gastroprotective Agent and H2-Receptor Antagonist on Preventative and Therapeutic Effects Against Gastroduodenal Mucosal Damage in Patients Taking Low-Dose Aspirin:a Prospective, Randomized, Multicenter, Controlled Trial

2013 ◽  
Vol 77 (5) ◽  
pp. AB265
Author(s):  
Toshihisa Takeuchi ◽  
Kazuhiro Ota ◽  
Satoshi Harada ◽  
Shoko Edogawa ◽  
Yuichi Kojima ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Low Dose ◽  
Controlled Trial ◽  
Mucosal Damage ◽  
Therapeutic Effects ◽  
H2 Receptor Antagonist ◽  
H2 Receptor ◽  
Gastroprotective Agent

Randomized controlled trial of an H2-receptor antagonist in gastric cancer

1997 ◽  
Vol 84 (8) ◽  
pp. 1168-1169 ◽  
Author(s):  
H. A. Wotherspoon ◽  
J. R. Anderson ◽  
C. G. Morran ◽  
G. D. Murray ◽  
C. S. McArdle
Keyword(s):  
Gastric Cancer ◽  
Randomized Controlled Trial ◽  
Receptor Antagonist ◽  
Controlled Trial ◽  
H2 Receptor Antagonist ◽  
H2 Receptor ◽  
Randomized Controlled

Randomized controlled trial of an H2 -receptor antagonist in gastric cancer

1997 ◽  
Vol 84 (8) ◽  
pp. 1168-1169
Author(s):  
H. A. Wotherspoon ◽  
J. R. Anderson ◽  
C. G. Morran ◽  
G. D. Murray ◽  
C. S. McArdle
Keyword(s):  
Gastric Cancer ◽  
Randomized Controlled Trial ◽  
Receptor Antagonist ◽  
Controlled Trial ◽  
H2 Receptor Antagonist ◽  
H2 Receptor ◽  
Randomized Controlled

The metabolism in animals and man of oxmetidine—A new histamine H2-receptor antagonist

Xenobiotica ◽  
1984 ◽  
Vol 14 (7) ◽  
pp. 509-514 ◽  
Author(s):  
P. J. Cox ◽  
W. M. H. Heijbroek ◽  
D. C. Taylor ◽  
P. J. Wood ◽  
P. R. Cresswell ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
H2 Receptor Antagonist ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
Histamine H2 Receptor Antagonist

Role of histamine H1- and H2-receptors in myoelectric activity of small bowel in the dog

1980 ◽  
Vol 238 (1) ◽  
pp. G50-G56
Author(s):  
S. J. Konturek ◽  
R. Siebers
Keyword(s):  
Small Bowel ◽  
Receptor Antagonist ◽  
Intestinal Motility ◽  
Receptor Agonist ◽  
Physiological Role ◽  
Myoelectric Activity ◽  
H1 Receptor ◽  
H2 Receptor Antagonist ◽  
H2 Receptor ◽  
H2 Receptors

Studies were conducted in conscious dogs implanted with monopolar silver electrodes along the small intestine to determine whether the intestinal motility response to histamine is mediated by H1-receptors alone or whether H2-receptors are also involved in the response. Histamine infusion alone induced a marked increase in the appearance rate and the propagation velocity of the interdigestive myoelectric complexes (IMC). This effect was reproduced by the administration of the selective H1-receptor agonist, 2-methylhistamine, and abolished by the H1-receptor antagonist, tripelennamine. Tripelennamine alone decreased the frequency of occurrence of the IMC in fasted animals and reduced significantly the spike potential activity of the small bowel in fed dogs. Neither the H2-receptor agonist, dimaprit, nor the H2-receptor antagonist, metiamide, had any influence on the motility patterns in fasted or fed animals. We conclude that histamine influences the patterns of small bowel motility via stimulation of H1-receptors but its physiological role in modulating intestinal motility remains to be determined.

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