288: Improved Clinical Outcomes Using Bi-Ventricular Assist Devices as Bridges to Transplant in Critically Ill Patients

2008 ◽  
Vol 27 (2) ◽  
pp. S164
Author(s):  
J. Moriguchi ◽  
M. Kwon ◽  
M. Plunkett ◽  
F. Esmailian ◽  
R. Jocson ◽  
...  
2017 ◽  
Vol 60 (4) ◽  
pp. 236-246 ◽  
Author(s):  
Sneha Raju ◽  
Jane MacIver ◽  
Farid Foroutan ◽  
Carolina Alba ◽  
Filio Billia ◽  
...  

2018 ◽  
Author(s):  
Brett A Melnikoff ◽  
René P Myers

Fungal infections remain an important cause of morbidity and mortality in surgical settings, with critically ill patients, transplant recipients, and sick neonates all especially vulnerable. Over the past few decades, technological and scientific advancements have improved physicians’ ability to sustain life in critically ill patients; developments in chemotherapeutics and immune-based therapies have yielded increased survival for many cancer patients; organ transplantation has evolved dramatically; and the use of invasive therapies (eg, ventricular assist devices) has increased markedly. With these changes has come an increase in the incidence of serious fungal infections, including the less common but potentially fatal noncandidal infections caused by Aspergillus and the Zygomycetes Mucor and Rhizopus. This review outlines an approach to the workup and management of the nonneutropenic surgical patient with a suspected noncandidal infection (aspergillosis and zygomycosis). Figures show biopsy samples from an elderly man with chronic progressive disseminated histoplasmosis and thick-walled, broad-based budding yeasts typical for Blastomyces dermatitidis on biopsy material. This review contains 2 figures and 47 references Key words: aspergillosis, aspergillosis prophylaxis, blastomycosis, Cryptococcus, histoplasmosis, noncandidal fungal infections  


2018 ◽  
Author(s):  
Brett A Melnikoff ◽  
René P Myers

Fungal infections remain an important cause of morbidity and mortality in surgical settings, with critically ill patients, transplant recipients, and sick neonates all especially vulnerable. Over the past few decades, technological and scientific advancements have improved physicians’ ability to sustain life in critically ill patients; developments in chemotherapeutics and immune-based therapies have yielded increased survival for many cancer patients; organ transplantation has evolved dramatically; and the use of invasive therapies (eg, ventricular assist devices) has increased markedly. With these changes has come an increase in the incidence of serious Candida infections. This review covers the definition and classification, epidemiology and risk factors, and clinical evaluation of candidiasis, as well as management of candidemia, acute disseminated candidiasis, nonhematogenous candidiasis, and peritonitis and intra-abdominal abscess. Figures show Candida endophthalmitis in patients with persistent fungemia and superficial candidiasis in the gastrointestinal tract. Tables list clinical presentation and diagnostic methods for common fungal infections, antimicrobial agents of choice for candidal infections, and the latest guidelines for candidiasis. This review contains 2 figures, 3 tables and 131 references Key words: acute disseminated candidiasis, candidemia, candidiasis, candiduria, nonhematogenous candidiasis  


2018 ◽  
Vol 41 (11) ◽  
pp. 1463-1467 ◽  
Author(s):  
Mustafa M. Ahmed ◽  
Stephen M. Magar ◽  
Eric I. Jeng ◽  
George J. Arnaoutakis ◽  
Thomas M. Beaver ◽  
...  

2021 ◽  
Author(s):  
Nina Buchtele ◽  
Thomas Staudinger ◽  
Anne-Kristin Schäfer ◽  
Magdalena Sophie Bögl ◽  
Christian Schoergenhofer ◽  
...  

Abstract (English)Extracorporeal circuits including renal replacement therapy, extracorporeal membrane oxygenation, and ventricular assist devices are increasingly used in critically ill patients. The need for anticoagulation to provide circuit patency and avoid thrombosis remains a challenging task for treating physicians. In the presence of overall low scientific evidence concerning the optimal anticoagulants, monitoring tests, and therapeutic target ranges, recommendations are largely expert opinions and most centers use individual “in-house” anticoagulation protocols. This review gives a practical view on current concepts of anticoagulation strategies in patients with extracorporeal assist devices.


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