scholarly journals Dissecting Serial Immune Response Stages of Chronic Rejection after Murine Orthotopic Lung Transplantation

2021 ◽  
Vol 40 (4) ◽  
pp. S305-S306
Author(s):  
T. Heigl ◽  
J. Kaes ◽  
C. Aelbrecht ◽  
G. Vande Velde ◽  
A. Vanstapel ◽  
...  
Keyword(s):  
Immune Response ◽  
Lung Transplantation ◽  
Chronic Rejection

scholarly journals RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 70
Author(s):  
Malgorzata Kloc ◽  
Ahmed Uosef ◽  
Martha Villagran ◽  
Robert Zdanowski ◽  
Jacek Z. Kubiak ◽  
...  
Keyword(s):  
Immune Response ◽  
Circadian Rhythm ◽  
Immune Cells ◽  
Chronic Rejection ◽  
Cardiac Transplantation ◽  
Small Gtpase ◽  
Eukaryotic Cells ◽  
Transplantation Model

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As such, they also regulate the phenotypes and functions of macrophages in the immune response and beyond. Here, we review the results of our and other’s studies on the role of the actin and RhoA pathway in shaping the macrophage functions in general and macrophage immune response during the development of chronic (long term) rejection of allografts in the rodent cardiac transplantation model. We focus on the importance of timing of the macrophage functions in chronic rejection and how the circadian rhythm may affect the anti-chronic rejection therapies.

Donor Brain Death Aggravates Chronic Rejection after Lung Transplantation in Rats

2004 ◽  
Vol 78 (9) ◽  
pp. 1251-1258 ◽  
Author(s):  
No??lle Zweers ◽  
Arjen H. Petersen ◽  
Joost A.B. van der Hoeven ◽  
Aalzen de Haan ◽  
Rutger J. Ploeg ◽  
...  
Keyword(s):  
Brain Death ◽  
Lung Transplantation ◽  
Chronic Rejection

Early Treatment of Acute Rejection Prevents Chronic Rejection in a Rat Model of Allogenic Left Lung Transplantation

1998 ◽  
Vol 30 (4) ◽  
pp. 1005-1006 ◽  
Author(s):  
S.W Hirt ◽  
X.M You ◽  
F Möller ◽  
K Boeke ◽  
M Ernst ◽  
...  
Keyword(s):  
Acute Rejection ◽  
Lung Transplantation ◽  
Rat Model ◽  
Early Treatment ◽  
Chronic Rejection ◽  
Left Lung

scholarly journals A Promoter Polymorphism in theCD59Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation

2015 ◽  
Vol 16 (3) ◽  
pp. 987-998 ◽  
Author(s):  
K. Budding ◽  
E. A. van de Graaf ◽  
T. Kardol-Hoefnagel ◽  
J. C. A. Broen ◽  
J. M. Kwakkel-van Erp ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Chronic Rejection ◽  
Protein Gene ◽  
Regulatory Protein ◽  
Promoter Polymorphism

scholarly journals Lung transplantation: chronic rejection and stem cell depletion

2018 ◽  
Vol 10 (8) ◽  
pp. E666-E668
Author(s):  
Thomas J. Lynch ◽  
Bethany A. Ahlers ◽  
Kalpaj R. Parekh
Keyword(s):  
Stem Cell ◽  
Lung Transplantation ◽  
Chronic Rejection ◽  
Cell Depletion

scholarly journals THE ROLE OF MYCOPHENOLATE MOFETIL IN THE PREVENTION OF CHRONIC REJECTION AFTER ALLOGENEIC LUNG TRANSPLANTATION IN RATS

2004 ◽  
Vol 78 ◽  
pp. 600-601
Author(s):  
T Pühler ◽  
S W. Hirt ◽  
E Lesser ◽  
M Frahm ◽  
C Hass ◽  
...  
Keyword(s):  
Mycophenolate Mofetil ◽  
Lung Transplantation ◽  
Chronic Rejection

scholarly journals Genetic variation in interleukin-17 receptor A is functionally associated with chronic rejection after lung transplantation

2013 ◽  
Vol 32 (12) ◽  
pp. 1233-1240 ◽  
Author(s):  
David Ruttens ◽  
Els Wauters ◽  
Michal Kiciński ◽  
Stijn E. Verleden ◽  
Elly Vandermeulen ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Lung Transplantation ◽  
Chronic Rejection ◽  
Interleukin 17

Increased Acid Exposure on Pretransplant Impedance-pH Testing Is Associated With Chronic Rejection After Lung Transplantation

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Wai-Kit Lo ◽  
Anna Moniodis ◽  
Hilary J. Goldberg ◽  
Natan Feldman ◽  
Walter W. Chan
Keyword(s):  
Lung Transplantation ◽  
Chronic Rejection ◽  
Acid Exposure
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