scholarly journals Prevention of white spot lesions around orthodontic brackets using organoselenium-containing antimicrobial enamel surface sealant

Heliyon ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e06490
Author(s):  
Bennett T. Amaechi ◽  
Brandon McGarrell ◽  
Minh N. Luong ◽  
Linda O. Okoye ◽  
Peter T. Gakunga
2012 ◽  
Vol 83 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Lauren Manfred ◽  
David A. Covell ◽  
Jennifer J. Crowe ◽  
Eser Tufekci ◽  
John C. Mitchell

Abstract Objective: To compare changes in enamel microhardness adjacent to orthodontic brackets after using bonding agents containing various compositions of bioactive glass compared to a traditional resin adhesive following a simulated caries challenge. Materials and Methods: Extracted human third molars (n  =  10 per group) had orthodontic brackets bonded using one of four novel bioactive glass (BAG)-containing orthodontic bonding agents (BAG-Bonds) or commercially available Transbond-XT. The four new adhesives contained BAG in varying percentages incorporated into a traditional resin monomer mixture. Teeth were cycled through low-pH demineralizing and physiologic-pH remineralizing solutions once each day over 14 days. Microhardness was measured on longitudinal sections of the teeth 100, 200, and 300 µm from the bracket edge and beneath the brackets, at depths of 25 to 200 µm from the enamel surface. Normalized hardness values were compared using three-way analysis of variance. Results: Significantly less reduction in enamel microhardness was found with the experimental adhesives at depths of 25 and 50 µm at all distances from the bracket edge. In all groups, there were no significant changes in enamel microhardness past 125-µm depth. Results varied with the different BAG-Bonds, with 81BAG-Bond showing the smallest decrease in enamel microhardness. Conclusions: The BAG-Bonds tested in this study showed a reduction in the amount of superficial enamel softening surrounding orthodontic brackets compared to a traditional bonding agent. The results indicate that clinically, BAG-Bonds may aid in maintaining enamel surface hardness, therefore helping prevent white spot lesions adjacent to orthodontic brackets.


2018 ◽  
Vol 9 ◽  
pp. 114
Author(s):  
Novira Mutia Safitri ◽  
Haru Setyo Anggani ◽  
Miesje Karmiati Purwanegara ◽  
Sariesendy Sumardi

Objectives: White spot lesions after fixed orthodontic treatment will increase bacterial plaque formation due to increased enamel surface roughness. The aim of this study was to analyze the surface roughness of white spot lesions on enamel after a microabrasion technique, a microabrasion technique combined with calcium phosphopeptide-amorphous calcium phosphate (CPP-ACP) application, and a microabrasion technique combined with fluoride application.Methods: Artificially induced white spot lesions on the enamel surfaces of 42 maxillary first premolars were randomly assigned into one of three treatment groups (n=14): (a) A microabrasion technique, (b) a microabrasion technique combined with CPP-ACP application, and (c) a microabrasion technique combined with fluoride application. A Mitutoyo SJ-301 surface roughness tester was used to measure differences in surface roughness before and after treatment, and the after treatment measurements were compared among the three groups.Results: A significant difference in surface roughness was noted for the white spot lesions on enamel before and after treatment in all groups (p<0.05). A significant difference was also found when comparing the after treatment surface roughness in all groups.Conclusion: The combination of the microabrasion technique with CPP-ACP application significantly reduced enamel surface roughness when compared to microabrasion alone or the combination of microabrasion and fluoride application.


2010 ◽  
Vol 21 (3) ◽  
pp. 211-215 ◽  
Author(s):  
Paula Passalini ◽  
Tatiana Kelly da Silva Fidalgo ◽  
Erika Machado Caldeira ◽  
Rogerio Gleiser ◽  
Matilde da Cunha Gonçalves Nojima ◽  
...  

The aim of the present study was to evaluate the in vitro caries preventive effect of fluoridated orthodontic resins under pH cycling with two types of acid demineralizing saliva. Brackets were bonded to 60 bovine incisors, using either Transbond Plus Color Change (n=30) or Orthodontic Fill Magic (n=30) orthodontic resins. Each group of resin was divided into 3 subgroups (n=10): immersion in remineralizing artificial saliva for 14 days, pH cycling with high cariogenic challenge in acid saliva with pH 5.5, and acid saliva with pH 4.5. After 14 days of pH cycling, the caries preventive effect on the development of white spot lesion was evaluated considering the presence of inhibition zones to white spot lesions using two scores: 0= absence and 1= presence. Kruskal Wallis and Mann-Whitney tests (a=0.05) were used. Formation of white spot lesions was observed only under pH cycling using acid saliva with pH 4.5; with Transbond Plus Color Change being significantly more effective (p<0.05) in preventing the appearance of white spot lesions effect than Orthodontic Fill Magic. The acidity of the demineralizing solution influenced the formation of white spot lesions around orthodontic brackets under highly cariogenic conditions. Transbond Plus Color Change resin presented higher caries preventive effect than Orthodontic Fill Magic.


2008 ◽  
Vol 78 (4) ◽  
pp. 585-590 ◽  
Author(s):  
Christos Livas ◽  
Anne Marie Kuijpers-Jagtman ◽  
Ewald Bronkhorst ◽  
Aniek Derks ◽  
Christos Katsaros

1996 ◽  
Vol 23 (1) ◽  
pp. 43-47 ◽  
Author(s):  
C. A. Melrose ◽  
J. Appleton ◽  
B. B. J. Lovius

A clinical trial was conducted to investigate the development of caries lesions associated with fixed orthodontic appliance therapy. To introduce a cariogenic challenge on Sound buccal enamel surface in vivo, specially designed orthodontic bands were attached to premolars scheduled for extraction for orthodontic reasons. The bands were modified by having two metal wires (0·8 mm in diameter) welded to the inner surface of the band to produce a space for plaque accumulation similar to that occurring under loose orthodontic bands. The bands were cemented with a zinc phosphate cement (Tenet®) an left in situ for 4 weeks. Of 22 premolar teeth banded in eight different patients, eight showed definite white spot lesions, eight showed definite faint enamel opacities, and six showed no discernable lesions. Examination of definite white spot lesions by scanning electron microscopy revealed characteristic patterns of initial tissue destruction. Focal holes and an accentuation of the perikymata were observed affecting the enamel surface zone, an area previously considered to remain relatively intact during the development of a caries lesion. The superficial nature of the caries lesions observed and the rapidly of their formation is significant in the clinical management of decalcified areas forming beneath orthodontics bands.


2016 ◽  
Vol 40 (4) ◽  
pp. 274-280 ◽  
Author(s):  
M Restrepo ◽  
D G Bussaneli ◽  
F Jeremias ◽  
RCL Cordeiro ◽  
DB Raveli ◽  
...  

Objective: To compare the effectiveness of fluoride varnish and 2% chlorhexidine gel for controlling active white spot lesions (WSLs) adjacent to orthodontic brackets. Study design: Thirty-five orthodontic patients (17.2 ± 2.3 years old) presenting 60 WSLs adjacent to orthodontic brackets were enrolled in this randomized, blind, 3-armed and controlled clinical trial. The patients were randomly allocated to 1 of 3 arms: (1) two applications of 5% NaF varnish- F, with one-week interval, (2) two applications of 2% chlorhexidine gel-CHX, with one-week interval and (3) usual home care-control (CO). The WSLs were scored by using a DIAGNOdent pen. An independent examiner scored the surfaces using Nyvad criteria for caries assessment. Results: A total of thirty patients presenting 51 lesions completed the study. All treatments reduced the fluorescence values during the experimental period; however, F induced faster remineralization than CHX. After 3 months, 70.58 % were inactive considering all groups. DIAGNOdent pen and Nyvad presented a significant correlation. Conclusion: After 3 months of treatment, F, CHX and CO were capable of controlling the WSLs adjacent to the orthodontic brackets. However, the treatment with F was capable of controlling the progression of the WSLs in a shorter period of time.


2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Selda Lale ◽  
Hikmet Solak ◽  
Evren Hınçal ◽  
Levent Vahdettin

One common negative side effect of orthodontic treatment with fixed appliances is the development of white spot lesions (WSLs) around brackets. This study is aimed at comparing the efficacy of various oral hygiene practices in preventing enamel demineralization around orthodontic brackets under similar in vitro conditions. The study included 90 extracted bovine incisors, which were randomized into six groups: fluoride toothpaste (FT), nonfluoride toothpaste (NFT), fluoride varnish plus fluoride toothpaste (FV+FT), CPP-ACP varnish plus fluoride toothpaste (CPP-ACP+FT), medical minerals gel plus nonfluoride toothpaste (MMG+NFT), and no intervention (control). All groups were subjected to demineralization and remineralization cycles. Visual appraisals were used to evaluate the changes in the enamel surface appearance at the beginning and end of the experiment. The changes in the demineralization degree were evaluated by measuring the Ca+2 concentration in the demineralization solution at different time points. The majority of teeth in the CPP-ACP+FT group exhibited no shift in appearance, whereas in the other groups, a slight change in enamel translucency was observed. At all the time points, the Ca+2 concentration in the demineralization solution in the CPP-ACP+FT group was the least among all other groups. At day 5, MMG+NFT’s preventive efficacy was significantly higher than FV+FT’s, but at days 10, 15, and 19, their efficacy was similar. However, at all the time points, MMG+NFT’s efficacy was significantly higher than that of control, whereas FV+FT’s efficacy was decreased at days 10, 15, and 19 and was close to the efficacy of control. To fight WSLs, early diagnosis was of great importance and examination of the tooth surface after air-drying for 5 s was recommended.


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