Rhus chinensis Mill.: A medicinal plant with promising inhibition of calcium oxalate crystallization, an in-vitro study

2021 ◽  
pp. 100489
Author(s):  
Memthoi Devi Heirangkhongjam ◽  
Iboyaima Singh Ngaseppam
Renal Failure ◽  
2018 ◽  
Vol 40 (1) ◽  
pp. 298-305 ◽  
Author(s):  
Mahboubeh Yousefi Ghale-Salimi ◽  
Maryam Eidi ◽  
Nasser Ghaemi ◽  
Ramezan Ali Khavari-Nejad

2010 ◽  
Vol 42 (5) ◽  
pp. 280 ◽  
Author(s):  
A Mitra ◽  
IniyanG Tamil ◽  
B Dineshkumar ◽  
M Nandhakumar ◽  
M Senthilkumar

2014 ◽  
Vol 155 (1) ◽  
pp. 599-606 ◽  
Author(s):  
Delgerbat Boldbaatar ◽  
Hesham R. El-Seedi ◽  
Meriana Findakly ◽  
Safa Jabri ◽  
Batkhuu Javzan ◽  
...  

Author(s):  
R. Srikaran ◽  
S. Salika Dulanjali

Objective: This in vitro study was carried out to evaluate the anti-urolithiatic activity of the methanolic extract of the Cucumismelo seeds on experimentally prepared calcium oxalate crystals which was prepared by the homogeneous precipitation method in the laboratory.Methods: The crude extract was prepared by the soxhlet extraction method and the extraction was done until all the compounds get extracted into the solution and solvent was evaporated by rotary evaporator. Extracts were stored in an airtight light-resistant container at 4 °C in a refrigerator for further analysis.Results: Seed extract of Cucumismelo showed maximum efficiencies in the dissolution of the calcium oxalate crystals. Cystone drug was used as the standard. This in vitro study has shown that the methanolic extract of the seeds of Cucumismelo has the potential anti-urolithiatic activity when compared with the standard.Conclusion: This in vitro study has given the primary evidence that the extract of seeds of Cucumismelo has the anti-urolithiatic activity. In vivo studies can be carried out on the seed extract of Cucumismelo for further investigations.


2021 ◽  
pp. 73-76
Author(s):  
Mugdhakumari R. Patel ◽  
Tanveer A. Khan ◽  
Ajay Namdeo ◽  
Chetan H. Shinde

Background: Around 12% of world population has been infected by renal stone disease which has multiphase etiological factors with high recurrence rate. Thus, in order to reduce the recurrence rate, use of homoeopathic intervention can be the most effective alternative option and Sarsaparilla is one of the frequently prescribed medicines by homoeopath in renal stones. Aim: To nd out the inhibitory action of homoeopathic medicine Sarsaparilla Q, 6C, 12C, 30C, 200C, 1M on calcium oxalate and calcium phosphate crystallization by in vitro study. Methodology: In vitro crystallisation of calcium oxalate and calcium phosphate was carried out to evaluate effectiveness of Homoeopathic Medicine Sarsaparilla as an inhibitor. Calcium Oxalate crystallisation assay was experimented by using JASCO-UV/VISIBLE-630 Spectrophotometer. Slope of Nucleation and Aggregation phases is calculated using linear regression analysis and percentage of inhibition was calculated. Calcium phosphate crystallisation inhibition by Sarsaparilla was calculated by measuring concentration of calcium and phosphate ions, using Digital Photo colorimeter by Trinder and Gomeri method respectively. Antioxidant activity of Sarsaparilla Mother Tincture and potencies was measured by DPPH free radical scavenging assay by spectrophotometer. Result: Maximum inhibition of calcium oxalate crystallisation has been noticed in Sarsaparilla Mother Tincture and 1M potency. While Sarsaparilla 30C showing maximum inhibition of Calcium Phosphate crystallisation. Sarsaparilla mother tincture was able to decolorize during DPPH assay in which Inhibition % was decreased as potency increased (Q>30C>1M). Conclusion: The present in vitro study has shown potential role of Homoeopathic medicine Sarsaparilla as an inhibitor of calcium oxalate and calcium phosphate crystallisation.


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