The impact of gastrojejunostomy orientation on delayed gastric emptying after pancreaticoduodenectomy: a single center comparative analysis

Abstract Nasogastric tubes (NGTs) and pyloric intervention in oesophagectomy are used to lessen the impact of gastric tube distention and delayed gastric emptying. However, their utility remains unclear, with mixed evidence and some studies suggesting they may increase morbidity and patient discomfort. We performed a national survey of tertiary oesophageal surgery centres to assess current practice and surgeon equipoise for a potential prospective trial. Methods An electronic survey was distributed to all oesophageal resection centres in England, Wales and Scotland. Included questions assessed centres’ use of NGTs, current practice for removal and dietary progression, and use of pyloric interventions. Variations in practice were assessed, and compared to nationally reported annual centre volumes and length of stay. Results Seventy-nine percent (31/39) of all centres responded to the survey. All centres reported routinely using an NGT. Most centres (19/31, 61%) did not perform pyloric intervention or routine post-operative radiological assessment (22/31, 71%). Criteria for NGT removal and dietary progression was highly variable, with every centre reporting different practice criteria. There were no trends for practices when comparing high vs low volume centres, or above vs at-or-below median length of stay. 21/31 (68%) centres were willing to take part in a trial to assess NGT use and pyloric interventions. Conclusion NGTs remain standard practice despite mixed evidence for their efficacy and an absence of standardisation in their use. Use of pyloric intervention varies widely, with no clear link to outcomes. Surgeons recognise the need for a trial to assess requirement for NGTs and pyloric intervention after oesophageal resection.

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The Impact of Preoperative Biliary Drainage on Postoperative Outcomes after Pancreaticoduodenectomy: A Single Center Retrospective Study

10.21203/rs.3.rs-136195/v1 ◽

2020 ◽

Author(s):

Daihai Mo ◽

Hongyun Ma ◽

Zhen Wang ◽

Jiayang Hu ◽

Gang Li

Keyword(s):

Gastric Emptying ◽

Obstructive Jaundice ◽

Biliary Drainage ◽

Multivariate Regression ◽

Delayed Gastric Emptying ◽

Multivariate Regression Analysis ◽

Preoperative Biliary Drainage ◽

Short Term ◽

Independent Risk Factors ◽

The Impact

Abstract Background The effect of preoperative biliary drainage (PBD) on the short-term outcomes after pancreaticoduodenectomy (PD) remains controversial. Methods 164 consecutive patients with obstructive jaundice who underwent PD in our center from 2016 to 2017 were retrospectively analyzed. The 120 patients who underwent PBD prior to PD (PBD group) were compared with 44 patients who did not (DS group). The short-term outcomes include overall morbidity, severe complications, postoperative pancreatic fistula(POPF), postpancreatectomy hemorrhage(PPH), intra-abdominal abscess (IAA), sepsis, delayed gastric emptying (DGE), postoperative hospital stay and 90-day death were assesed. Results There were no significant statistical differences in overall morbidity, severe complications, POPF, PPH, IAA, LOS and ninety-day mortality between two groups. The incidence of DGE in PBD group was significantly lower than that in DS group (4.5% vs. 19.2%, P = 0.021). Multivariate regression analysis showed that age over 66 years (OR: 3.094,95% CI: 1.268-7.55) and direct surgery (OR: 5.298, 95% CI: 1.176-23.865) were independent risk factors for DGE. Conclusion For patients with obstructive jaundice, preoperative biliary drainage is independently associated with delayed gastric emptying, but does not affect the overall morbidity and mortality of patients undergoing PD.

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P-P03 Impact of routine nasogastric decompression versus no nasogastric decompression after pancreatoduodenectomy on perioperative outcomes: A meta-analysis of available evidence

British Journal of Surgery ◽

10.1093/bjs/znab430.227 ◽

2021 ◽

Vol 108 (Supplement_9) ◽

Author(s):

Khaled Ammar ◽

Chris Varghese ◽

Thejasvin K ◽

Viswakumar Prabakaran ◽

Stuart Robinson ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Meta Analysis ◽

Length Of Hospital Stay ◽

Postoperative Pancreatic Fistula ◽

Current Evidence ◽

Perioperative Outcomes ◽

The Impact ◽

Nasogastric Decompression

Abstract Background This meta-analysis reviewed the current evidence on the impact of routine Nasogastric decompression (NGD) versus no NGD after pancreatoduodenectomy on perioperative outcomes. Methods PubMed, Medline, Scopus, Embase and Cochrane databases were searched for studies reporting the role of nasogastric tube decompression after pancreatoduodenectomy on perioperative outcomes were retrieved and analysed up to January 2021. Results Eight studies with total of 1301 patients were enrolled of which 668 patients had routine NGD. Routine NGD was associated with a higher incidence of overall delayed gastric emptying (DGE) and clinically relevant DGE (OR = 2.51, 95% CI; 1.12 - 5.63, I2= 83%, P = 0.03, and OR = 3.64, 95% CI: 1.83 – 7.25, I2 = 54%, P < 0.01, respectively). Routine NGD was also associated with a higher rate of Clavien-Dindo ≥ 2 complications (OR = 3.12, 95% CI: 1.05 – 9.28, I2 = 88%, P = 0.04), and increased length of hospital stay (MD = 2.67, 95% CI: 0.60 – 4.75, I2 = 97%, P = 0.02). There were no significant differences in overall complications (OR = 1.07, 95% CI: 0.79 – 1.46, I2 0%, P = 0.66), or postoperative pancreatic fistula (OR = 1.21, 95% CI: 0.86 – 1.72, I2 = 0%, P = 0.28) between the two groups. Conclusions Routine NGD may be associated with increased rates of DGE, major complications and longer length of stay after pancreatoduodenectomy.

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