Human leukocyte antigen-A, -B, and -DRB1 haplotypes of cord blood units in the Tzu Chi Taiwan Cord Blood Bank

2008 ◽  
Vol 69 (7) ◽  
pp. 430-436 ◽  
Author(s):  
Shu-Hui Wen ◽  
Meng-Jiun Lai ◽  
Kuo-Liang Yang
Keyword(s):  
Human Leukocyte Antigen ◽  
Cord Blood ◽  
Human Leukocyte ◽  
Blood Bank ◽  
Leukocyte Antigen ◽  
Cord Blood Bank ◽  
Antigen A

Allele and Haplotype Frequencies of Human Leukocyte Antigen-A, -B, and -DR Loci in Koreans: DNA Typing of 1,500 Cord Blood Units

2008 ◽  
Vol 28 (6) ◽  
pp. 465-474 ◽  
Author(s):  
Dong Hee Whang ◽  
Yun Sun Yang ◽  
Hye Kyung Hong
Keyword(s):  
Human Leukocyte Antigen ◽  
Cord Blood ◽  
Dna Typing ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Haplotype Frequencies ◽  
Antigen A

scholarly journals Human Leukocyte Antigen and Red Blood Cells Impact Umbilical Cord Blood CD34+ Cell Viability after Thawing

2019 ◽  
Vol 20 (19) ◽  
pp. 4875 ◽  
Author(s):  
Vanegas ◽  
Galindo ◽  
Páez-Gutiérrez ◽  
González-Acero ◽  
Medina-Valderrama ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Cell Viability ◽  
Cord Blood ◽  
Red Blood Cells ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Blood Cells ◽  
Human Leukocyte ◽  
Hla Typing ◽  
Leukocyte Antigen

Hematopoietic progenitor cell (HPC) transplantation is a treatment option for malignant and nonmalignant diseases. Umbilical cord blood (UCB) is an important HPC source, mainly for pediatric patients. It has been demonstrated that human leukocyte antigen (HLA) matching and cell dose are the most important features impacting clinical outcomes. However, UCB matching is performed using low resolution HLA typing and it has been demonstrated that the unnoticed mismatches negatively impact the transplant. Since we found differences in CD34+ viability after thawing of UCB units matched for two different patients (p = 0.05), we presumed a possible association between CD34+ cell viability and HLA. We performed a multivariate linear model (n = 67), comprising pre-cryopreservation variables and high resolution HLA genotypes separately. We found that pre-cryopreservation red blood cells (RBC), granulocytes, and viable CD34+ cell count significantly impacted CD34+ viability after thawing, along with HLA-B or -C (R2 = 0.95, p = 0.01; R2 = 0.56, p = 0.007, respectively). Although HLA-B*40:02 may have a negative impact on CD34+ cell viability, RBC depletion significantly improves it.

scholarly journals Performance Characteristics of Updated INNO-LiPA Assays for Molecular Typing of Human Leukocyte Antigen A (HLA-A), HLA-B, and HLA-DQB1 Alleles

2004 ◽  
Vol 11 (2) ◽  
pp. 430-432 ◽  
Author(s):  
Karen De Vreese ◽  
Rachel Barylski ◽  
Fiona Pughe ◽  
Miriam Bläser ◽  
Colin Evans ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
Human Leukocyte Antigen ◽  
Molecular Typing ◽  
Human Leukocyte ◽  
Performance Characteristics ◽  
Hla Typing ◽  
Tissue Typing ◽  
Leukocyte Antigen ◽  
Antigen A ◽  
Accuracy Rates

ABSTRACT We carried out a multicenter performance evaluation of three new DNA-based human leukocyte antigen (HLA) typing assays: INNO-LiPA HLA-A Update, INNO-LiPA HLA-B Update, and INNO-LiPA HLA-DQB1 Update. After optimization, the accuracy rates were all 100%, and the final observed resolutions were 99.4, 92.4, and 85.6%, respectively. These rapid and easy-to-perform assays yielded results fully concordant with other DNA-based tissue typing tests.

scholarly journals Allele and Haplotype Frequencies of Human Leukocyte Antigen-A, -B, -C, -DRB1, and -DQB1 From Sequence-Based DNA Typing Data in Koreans

2015 ◽  
Vol 35 (4) ◽  
pp. 429-435 ◽  
Author(s):  
Ji Won In ◽  
Eun Youn Roh ◽  
Sohee Oh ◽  
Sue Shin ◽  
Kyoung Un Park ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Dna Typing ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Haplotype Frequencies ◽  
Antigen A

Identification of novel immunogenic human leukocyte antigen-A*2402-binding epitopes of human papillomavirus type 16 E7 for immunotherapy against human cervical cancer

Cancer ◽  
2011 ◽  
Vol 118 (8) ◽  
pp. 2173-2183 ◽  
Author(s):  
Sunphil Jang ◽  
Young Tae Kim ◽  
Hye Won Chung ◽  
Kyoung-Ryul Lee ◽  
Jong-Baeck Lim ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Human Papillomavirus Type 16 ◽  
Antigen A ◽  
Human Cervical Cancer

Induction of human leukocyte antigen-A,B,C and -DR on cultured human oligodendrocytes and astrocytes by human γ-interferon

1986 ◽  
Vol 72 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Mikio Hirayama ◽  
Takashi Yokochi ◽  
Kaoru Shimokata ◽  
Mitsuo Iida ◽  
Norio Fujiki
Keyword(s):  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Antigen A ◽  
Human Oligodendrocytes ◽  
Γ Interferon
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