T cell receptor-associated protein tyrosine kinases: The dynamics of tolerance regulation by phosphorylation and its role in systemic lupus erythematosus

2014 ◽  
Vol 75 (9) ◽  
pp. 945-952 ◽  
Author(s):  
Ana Barrera-Vargas ◽  
Diana Gómez-Martín ◽  
Jorge Alcocer-Varela
Keyword(s):  
Systemic Lupus Erythematosus ◽  
T Cell ◽  
T Cell Receptor ◽  
Lupus Erythematosus ◽  
Tyrosine Kinases ◽  
Cell Receptor ◽  
Protein Tyrosine Kinases ◽  
Systemic Lupus ◽  
Protein Tyrosine ◽  
Receptor Associated Protein

T-cell receptor and HLA class II RFLPs in systemic lupus erythematosus

1988 ◽  
Vol 27 (5) ◽  
pp. 392-395 ◽  
Author(s):  
H. Dunckley ◽  
P. A. Gatenby ◽  
S. W. Serjeantson
Keyword(s):  
Systemic Lupus Erythematosus ◽  
T Cell ◽  
T Cell Receptor ◽  
Lupus Erythematosus ◽  
Cell Receptor ◽  
Class Ii ◽  
Hla Class Ii ◽  
Systemic Lupus

Prevalence of T cell receptor ζchain deficiency in systemic lupus erythematosus

Lupus ◽  
2003 ◽  
Vol 12 (1) ◽  
pp. 46-51 ◽  
Author(s):  
M P Nambiar ◽  
J P Mitchell ◽  
R P Ceruti ◽  
M A Malloy ◽  
G C Tsokos
Keyword(s):  
Systemic Lupus Erythematosus ◽  
T Cell ◽  
T Cell Receptor ◽  
Lupus Erythematosus ◽  
Cell Receptor ◽  
Systemic Lupus

Modulation of T-cell receptor functional sensitivity via the opposing actions of protein tyrosine kinases and phosphatases: a mathematical model

2014 ◽  
Vol 6 (12) ◽  
pp. 1183-1195
Author(s):  
Barbara Szomolay ◽  
Hugo A. van den Berg
Keyword(s):  
Mathematical Model ◽  
T Cell ◽  
Phosphatase Activity ◽  
T Cell Receptor ◽  
Sensitivity And Specificity ◽  
Tyrosine Kinases ◽  
Cell Receptor ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Kinetic Proofreading

We extend the kinetic proofreading model of TCR triggering to show how phosphatase activity can modulate the TCR's sensitivity and specificity.

Mutations in T cell Receptor ζ Chain mRNA of Peripheral T cells from Systemic Lupus Erythematosus Patients

1998 ◽  
Vol 11 (5) ◽  
pp. 381-385 ◽  
Author(s):  
Kensei Tsuzaka ◽  
Tsutomu Takeuchi ◽  
Natsuko Onoda ◽  
Ming Pang ◽  
Tohru Abe
Keyword(s):  
Systemic Lupus Erythematosus ◽  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Lupus Erythematosus ◽  
Cell Receptor ◽  
Systemic Lupus ◽  
Peripheral T Cells
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