Preparation, characterization and evaluation of cellulose nanocrystal/poly(lactic acid) in situ nanocomposite scaffolds for tissue engineering

2019 ◽  
Vol 134 ◽  
pp. 469-479 ◽  
Author(s):  
Weihua Luo ◽  
Lianghao Cheng ◽  
Caixia Yuan ◽  
Zhiping Wu ◽  
Guangming Yuan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Cellulose Nanocrystal ◽  
Poly Lactic Acid ◽  
Nanocomposite Scaffolds

scholarly journals In Situ Cellulose Nanocrystal-Reinforced Glycerol-Based Biopolyester for Enhancing Poly(lactic acid) Biocomposites

ACS Omega ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 3857-3867 ◽  
Author(s):  
Elizabeth Brown ◽  
Mohamed Abdelwahab ◽  
Oscar Valerio ◽  
Manjusri Misra ◽  
Amar K. Mohanty
Keyword(s):  
Lactic Acid ◽  
Cellulose Nanocrystal ◽  
Poly Lactic Acid

Super‐tough poly(lactic acid) using a fully bio‐based polyester containing malic acid via in‐situ interfacial compatibilization

2021 ◽  
pp. 51413
Author(s):  
Rong Yang ◽  
Hongwei Cao ◽  
Chong Li ◽  
Guoxiang Zou ◽  
Xin Zhang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Malic Acid ◽  
Poly Lactic Acid

Development of three-dimensional printing filaments based on poly(lactic acid)/hydroxyapatite composites with potential for tissue engineering

2021 ◽  
pp. 002199832098856
Author(s):  
Marcela Piassi Bernardo ◽  
Bruna Cristina Rodrigues da Silva ◽  
Luiz Henrique Capparelli Mattoso
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
Poly Lactic Acid ◽  
Scanning Calorimetry ◽  
Three Dimensional Printing ◽  
Fused Deposition ◽  
Deposition Modeling ◽  
3D Printed

Injured bone tissues can be healed with scaffolds, which could be manufactured using the fused deposition modeling (FDM) strategy. Poly(lactic acid) (PLA) is one of the most biocompatible polymers suitable for FDM, while hydroxyapatite (HA) could improve the bioactivity of scaffold due to its chemical composition. Therefore, the combination of PLA/HA can create composite filaments adequate for FDM and with high osteoconductive and osteointegration potentials. In this work, we proposed a different approache to improve the potential bioactivity of 3D printed scaffolds for bone tissue engineering by increasing the HA loading (20-30%) in the PLA composite filaments. Two routes were investigated regarding the use of solvents in the filament production. To assess the suitability of the FDM-3D printing process, and the influence of the HA content on the polymer matrix, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) were performed. The HA phase content of the composite filaments agreed with the initial composite proportions. The wettability of the 3D printed scaffolds was also increased. It was shown a greener route for obtaining composite filaments that generate scaffolds with properties similar to those obtained by the solvent casting, with high HA content and great potential to be used as a bone graft.

Rheological and Thermo-Mechanical Properties of Poly(lactic acid)/Lignin-Coated Cellulose Nanocrystal Composites

2017 ◽  
Vol 5 (2) ◽  
pp. 1711-1720 ◽  
Author(s):  
Anju Gupta ◽  
William Simmons ◽  
Gregory T. Schueneman ◽  
Donald Hylton ◽  
Eric A. Mintz
Keyword(s):  
Mechanical Properties ◽  
Lactic Acid ◽  
Cellulose Nanocrystal ◽  
Poly Lactic Acid

Double yielding behavior of in situ microfibrillar polyolefin elastomer/poly(lactic acid) composites: Effect of microfibrillar morphology

2020 ◽  
Vol 60 (7) ◽  
pp. 1676-1685
Author(s):  
Jing Sun ◽  
Shanshan Luo ◽  
Anrong Huang ◽  
Min Shi ◽  
Heng Luo ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Poly Lactic Acid ◽  
Polyolefin Elastomer ◽  
Yielding Behavior

scholarly journals Morphology, Thermal, Mechanical Properties and Rheological Behavior of Biodegradable Poly(butylene succinate)/poly(lactic acid) In-Situ Submicrofibrillar Composites

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2422 ◽  
Author(s):  
Zhiwen Zhu ◽  
Hezhi He ◽  
Bin Xue ◽  
Zhiming Zhan ◽  
Guozhen Wang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Cold Drawing ◽  
Mechanical Analysis ◽  
Poly Lactic Acid ◽  
Fiber Morphology ◽  
Molding Process ◽  
Butylene Succinate ◽  
Low Frequencies ◽  
Biodegradable Poly

In this study, biodegradable poly(butylene succinate)/poly(lactic acid) (PBS/PLA) in-situ submicrofibrillar composites with various PLA content were successfully produced by a triple-screw extruder followed by a hot stretching−cold drawing−compression molding process. This study aimed to investigate the effects of dispersed PLA submicro-fibrils on the thermal, mechanical and rheological properties of PBS/PLA composites. Morphological observations demonstrated that the PLA phases are fibrillated to submicro-fibrils in the PBS/PLA composites, and all the PLA submicro-fibrils produced seem to have a uniform diameter of about 200nm. As rheological measurements revealed, at low frequencies, the storage modulus (G’) of PBS/PLA composites has been increased by more than four orders of magnitude with the inclusion of high concentrations (15 wt % and 20 wt %) of PLA submicro-fibrils, which indicates a significant improvement in the elastic responses of PBS melt. Dynamic Mechanical Analysis (DMA) results showed that the glass transition temperature (Tg) of PBS phase slightly shifted to the higher temperature after the inclusion of PLA. DSC experiments proved that fiber morphology of PLA has obvious heterogeneous nucleation effect on the crystallization of PBS. The tensile properties of the PBS/PLA in-situ submicrofibrillar composites are also improved compared to neat PBS.

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