Intelligent superabsorbents based on a xanthan gum/poly (acrylic acid) semi-interpenetrating polymer network for application in drug delivery systems

2019 ◽  
Vol 139 ◽  
pp. 509-520 ◽  
Author(s):  
Mohsen Hajikhani ◽  
Maryam Moradi Khanghahi ◽  
Mohsen Shahrousvand ◽  
Jamshid Mohammadi-Rovshandeh ◽  
Amir Babaei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Acrylic Acid ◽  
Xanthan Gum ◽  
Drug Delivery Systems ◽  
Polymer Network ◽  
Delivery Systems ◽  
Interpenetrating Polymer Network ◽  
Poly Acrylic Acid

Development of nanoparticulate drug delivery systems based on thiolated poly(acrylic acid)

2009 ◽  
Vol 26 (3) ◽  
pp. 187-194 ◽  
Author(s):  
Michael H. Thaurer ◽  
Britta Deutel ◽  
Wolfgang Schlocker ◽  
Andreas Bernkop-Schnürch
Keyword(s):  
Drug Delivery ◽  
Acrylic Acid ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Poly Acrylic Acid

Synthesis and Characteristics of Interpenetrating Polymer Network Hydrogels Based on Konjac Glucomannan with Different Molecular Weights and Poly(acrylic acid)

2011 ◽  
Vol 393-395 ◽  
pp. 1004-1007
Author(s):  
Xue Yao ◽  
Xue Gang Luo ◽  
Ben Chao Han
Keyword(s):  
Acrylic Acid ◽  
Enzymatic Degradation ◽  
Drug Carrier ◽  
Polymer Network ◽  
Konjac Glucomannan ◽  
Interpenetrating Polymer Network ◽  
Swelling Ratio ◽  
Molecular Weights ◽  
Ft Ir ◽  
Poly Acrylic Acid

Konjac glucomannan with different molecular weights/poly(acrylic acid) hydrogels were prepared in this paper. The structure of the IPN hydrogels was characterized by FT-IR and SEM. The swelling ratio of these hydrogels showed they had pH-sensitive properties and the enzymatic degradation tests showed the hydrogels retain the enzymatic degradation character of KGM. Furthermore, hydrogel composed of native KGM degraded sharply in enzymatic degradation test and it had bigger swelling ratio and weight loss ratio than those hydrogels which composed of lower molecular weights KGM. Therefore, hydrogels composed of lower molecular weight might release drug more stable when they were used as drug carrier.

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