Modified xanthan gum for methyl orange uptake: Kinetic, isotherm, and thermodynamic behaviors

2020 ◽  
Vol 165 ◽  
pp. 2442-2450
Author(s):  
Fengli Lian ◽  
Meixia Zheng ◽  
Meichun Chen ◽  
Yujing Zhu ◽  
Longtao Zhang ◽  
...  
Keyword(s):  
Methyl Orange ◽  
Xanthan Gum ◽  
Uptake Kinetic

Modified xanthan gum for crystal violet uptake: kinetic, isotherm, and thermodynamic behaviors

2019 ◽  
Vol 79 (1) ◽  
pp. 165-174 ◽  
Author(s):  
Meixia Zheng ◽  
Fengli Lian ◽  
Yujing Zhu ◽  
Bo Liu ◽  
Zheng Chen ◽  
...  
Keyword(s):  
Crystal Violet ◽  
Active Sites ◽  
Xanthan Gum ◽  
Maximum Adsorption Capacity ◽  
Hydroxyl Groups ◽  
X Ray Diffraction ◽  
Uptake Kinetic ◽  
Freundlich Isotherms ◽  
Pseudo Second Order ◽  
Kinetics Of

Abstract Modified xanthan gum (XG-AM-TTE) was employed as an adsorbent to study the adsorption behavior, thermodynamics and kinetics of crystal violet (CV) from an aqueous solution. Fourier transform infrared spectroscopy analysis indicates that the functional groups present in the adsorbent, such as carboxyl, ester and hydroxyl groups, are included on the external surface of the material, and these groups are potential active sites for interaction with CV. According to X-ray diffraction results, the structure of XG-AM-TTE after CV adsorption became more disordered, and the microstructure change is an indication of effective adsorption of CV to the surface, with CV becoming remarkably dispersed in the adsorbent according to the scanning electron microscopy observations. The adsorption kinetics and adsorption equilibrium were best described by the pseudo-second-order model and Freundlich isotherms, respectively. The thermodynamic parameters, as the Gibbs-free energy (ΔG), enthalpy (ΔH) and entropy (ΔS), indicated that the adsorption is a spontaneous, endothermic and entropy increase process. The maximum adsorption capacity of XG-AM-TTE was 183 ± 12 mg/g, suggesting that XG-AM-TTE is an efficient adsorbent.

Toxicological evaluation of xanthan gum based hydrogel formulation in Wistar rats using single dose study

2020 ◽  
Vol 77 (2) ◽  
pp. 353-360
Author(s):  
Nadia Malik ◽  
Mahmood Ahmad ◽  
Muhammad Minhas ◽  
Ruqia Tulain ◽  
Ikrima Khalid ◽  
...  
Keyword(s):  
Single Dose ◽  
Xanthan Gum ◽  
Wistar Rats ◽  
Toxicological Evaluation ◽  
Single Dose Study ◽  
Dose Study ◽  
Hydrogel Formulation

Controlled Release of Metformin Hydrochloride I. In vitro Release from Physical Mixture Containing Xanthan Gum as Hydrophilic Rate Retarding Polymer

1970 ◽  
Vol 4 (1) ◽  
Author(s):  
Mashkura Ashrafi ◽  
Jakir Ahmed Chowdhury ◽  
Md Selim Reza
Keyword(s):  
Controlled Release ◽  
Xanthan Gum ◽  
In Vitro Release ◽  
Correlation Coefficients ◽  
High Ratio ◽  
Water Soluble ◽  
Metformin Hydrochloride ◽  
Model Drug ◽  
Very High

Capsules of different formulations were prepared by using a hydrophilic polymer, xanthan gum and a filler Ludipress. Metformin hydrochloride, which is an anti-diabetic agent, was used as a model drug here with the aim to formulate sustained release capsules. In the first 6 formulations, metformin hydrochloride and xanthan gum were used in different ratio. Later, Ludipress was added to the formulations in a percentage of 8% to 41%. The total procedure was carried out by physical mixing of the ingredients and filling in capsule shells of size ‘1’. As metformin hydrochloride is a highly water soluble drug, the dissolution test was done in 250 ml distilled water in a thermal shaker (Memmert) with a shaking speed of 50 rpm at 370C &plusmn 0.50C for 6 hours. After the dissolution, the data were treated with different kinetic models. The results found from the graphs and data show that the formulations follow the Higuchian release pattern as they showed correlation coefficients greater than 0.99 and the sustaining effect of the formulations was very high when the xanthan gum was used in a very high ratio with the drug. It was also investigated that the Ludipress extended the sustaining effect of the formulation to some extent. But after a certain period, Ludipress did not show any significant effect as the pores made by the xanthan gum network were already blocked. It is found here that when the metformin hydrochloride and the xanthan gum ratio was 1:1, showed a high percentage of drug release, i.e. 91.80% of drug was released after 6 hours. But With a xanthan gum and metformin hydrochloride ratio of 6:1, a very slow release of the drug was obtained. Only 66.68% of the drug was released after 6 hours. The percent loading in this case was 14%. Again, when Ludipress was used in high ratio, it was found to retard the release rate more prominently. Key words: Metformin Hydrochloride, Xanthan Gum, Controlled release capsule Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

Removal of Methyl Orange from Aqueous Solutions by Using Zn-Al Layered Double Hydroxide as Photocatalyst

2015 ◽  
Vol 1 (2) ◽  
pp. 36-41
Author(s):  
Laura Cocheci ◽  
◽  
Ancuta-Corina Marcu ◽  
Paul Barvinschi ◽  
Aniela Pop
Keyword(s):  
Methyl Orange ◽  
Aqueous Solutions ◽  
Layered Double Hydroxide ◽  
Double Hydroxide

Preparation and Characterization of Polymer Blend (PVA/PEO) Filled with Methyl Orange Thin Films

2018 ◽  
Vol 14 (2) ◽  
pp. 221-234
Author(s):  
Ahmed Namah Mohamed ◽  
◽  
Jafer Fahdel Odah ◽  
Haider Tawfiq Naeem
Keyword(s):  
Thin Films ◽  
Methyl Orange ◽  
Polymer Blend

Formulation and Evaluation of Galantamine Hydrobromide Floating Matrix Tablet

2018 ◽  
Vol 8 (2) ◽  
Author(s):  
Poreddy Srikanth Reddy ◽  
Penjuri Subhash Chandra Bose ◽  
Vuppula Sruthi ◽  
Damineni Saritha
Keyword(s):  
Sodium Alginate ◽  
Xanthan Gum ◽  
Lag Time ◽  
Matrix Tablets ◽  
In Vitro Dissolution ◽  
Matrix Tablet ◽  
Compression Technique ◽  
Weight Variation ◽  
The Matrix

The aim of the present work was to prepare floating tablets of galantamine HBr using sodium alginate and xanthan gum as matrix forming carriers. Galantamine HBr is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments, in particular those of vascular origin. The matrix tablet formulations were prepared by varying the concentrations of sodium alginate and xanthan gum. The tablets were prepared by direct compression technique using PVP K-30 as a binder and sodium bicarbonate for development of CO2. The prepared matrix tablets were evaluated for properties such as hardness, thickness, friability, weight variation, floating lag time, compatibility using DSC and FTIR. In vitro dissolution was carried out for 12 hrs in 0.1N HCl at 37±0.5 ºC using USP paddle type dissolution apparatus. It was noted that, all the prepared formulations had desired floating lag time and constantly floated on dissolution medium by maintaining the matrix integrity. The drug release from prepared tablets was found to vary with varying concentration of the polymers, sodium alginate and xanthan gum. From the study it was concluded that floating drug delivery system for galantamine HBr can be prepared by using sodium alginate and xanthan gum as a carrier.

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