scholarly journals Latent tuberculosis infection in children and adolescents in Russia

2020 ◽  
Vol 92 ◽  
pp. S26-S30 ◽  
Author(s):  
Valentina Alexandrovna Aksenova ◽  
Irina Anatolievna Vasilyeva ◽  
Tereza Chermenovna Kasaeva ◽  
Anastasia Gennadievna Samoilova ◽  
Natalia Yurievna Pshenichnaya ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection

scholarly journals Gene expression in peripheral blood cells for differentiation of active and latent tuberculosis infection in children and adolescents

2020 ◽  
Vol 97 (12) ◽  
pp. 28-32
Author(s):  
A. A. Elov ◽  
M. A. Vladimirskiy ◽  
S. V. Smerdin ◽  
O. I. Elufimova
Keyword(s):  
Children And Adolescents ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Messenger Rna ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Active Tuberculosis ◽  
Tuberculosis Infection ◽  
Patient Treatment ◽  
Modified Method

The objective: to analyze the expression of certain genes in the blood cells of children and adolescence to differentiate the active and latent phases of tuberculosis infection.Subjects and methods. Peripheral blood samples collected in 36 pediatric patients with latent tuberculosis infection and 24 patients aged 1 to 16 years undergoing in-patient treatment for pulmonary tuberculosis were tested. A modified method for isolating messenger RNA and reverse transcriptional polymerase chain reaction was used to identify the transcription of six genes selected for analysis.Results. In a comparative study of the expression values of six promising genes in blood cells in the study of two groups of children and adolescents with latent and active tuberculosis infection, it was found that the most differentiating feature for determining active tuberculosis infection was a significantly higher level of expression of PDCD1 gene encoding PD1 lymphocyte receptor. At the same time, the sensitivity to detect the active infection was found to be 95.8%, specificity – 94.4%, the accuracy of the positive prognosis of active tuberculosis infection was 93.3%.

scholarly journals Abandonment of Treatment for Latent Tuberculosis Infection and Socioeconomic Factors in Children and Adolescents: Rio De Janeiro, Brazil

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0154843 ◽  
Author(s):  
Angela Marcia Cabral Mendonça ◽  
Afrânio Lineu Kritski ◽  
Marcelo Gerardin Poirot Land ◽  
Clemax Couto Sant’Anna
Keyword(s):  
Socioeconomic Factors ◽  
Children And Adolescents ◽  
Rio De Janeiro ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection

scholarly journals Serum anti-Mce1A immunoglobulin detection as a tool for differential diagnosis of tuberculosis and latent tuberculosis infection in children and adolescents

Tuberculosis ◽  
2020 ◽  
Vol 120 ◽  
pp. 101893 ◽  
Author(s):  
Christiane M. Schmidt ◽  
Kathryn L. Lovero ◽  
Fabiana R. Carvalho ◽  
Daniele C.M. dos Santos ◽  
Ana Cláudia M.W. Barros ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Children And Adolescents ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection

scholarly journals Performance of Commercial Blood Tests for the Diagnosis of Latent Tuberculosis Infection in Children and Adolescents

PEDIATRICS ◽  
2009 ◽  
Vol 123 (3) ◽  
pp. e419-e424 ◽  
Author(s):  
B. M. Bergamini ◽  
M. Losi ◽  
F. Vaienti ◽  
R. D'Amico ◽  
B. Meccugni ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
Blood Tests
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