scholarly journals Sub-Inhibitory concentrations of SOS-Response inducing antibiotics stimulate integrase expression and excision of pathogenicity islands in uropathogenic Escherichia coli strain 536

2020 ◽  
Vol 310 (1) ◽  
pp. 151361 ◽  
Author(s):  
Marco Chittò ◽  
Michael Berger ◽  
Luisa Klotz ◽  
Ulrich Dobrindt
Keyword(s):  
Escherichia Coli ◽  
Sos Response ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Pathogenicity Islands

Influence of pathogenicity islands and the minor leuX-encoded tRNA5Leu on the proteome pattern of the uropathogenic Escherichia coli strain 536

2000 ◽  
Vol 290 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Katharine Piechaczek ◽  
Ulrich Dobrindt ◽  
Angelika Schierhorn ◽  
Gunter S. Fischer ◽  
Michael Hecker ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Pathogenicity Islands

scholarly journals Regulation of Expression of the TIR-Containing Protein C Gene of the Uropathogenic Escherichia coli Strain CFT073

Pathogens ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 549
Author(s):  
Julia Ittensohn ◽  
Jacqueline Hemberger ◽  
Hannah Griffiths ◽  
Maren Keller ◽  
Simone Albrecht ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Protein C ◽  
Interleukin 1 ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Reporter Construct ◽  
Regulation Of Expression ◽  
E Coli ◽  
Strain Cft073 ◽  
Myeloid Differentiation Factor

The uropathogenic Escherichia coli strain CFT073 causes kidney abscesses in mice Toll/interleukin-1 receptor domain-containing protein C (TcpC) dependently and the corresponding gene is present in around 40% of E. coli isolates of pyelonephritis patients. It impairs the Toll-like receptor (TLR) signaling chain and the NACHT leucin-rich repeat PYD protein 3 inflammasome (NLRP3) by binding to TLR4 and myeloid differentiation factor 88 as well as to NLRP3 and caspase-1, respectively. Overexpression of the tcpC gene stopped replication of CFT073. Overexpression of several tcpC-truncation constructs revealed a transmembrane region, while its TIR domain induced filamentous bacteria. Based on these observations, we hypothesized that tcpC expression is presumably tightly controlled. We tested two putative promoters designated P1 and P2 located at 5′ of the gene c2397 and 5′ of the tcpC gene (c2398), respectively, which may form an operon. High pH and increasing glucose concentrations stimulated a P2 reporter construct that was considerably stronger than a P1 reporter construct, while increasing FeSO4 concentrations suppressed their activity. Human urine activated P2, demonstrating that tcpC might be induced in the urinary tract of infected patients. We conclude that P2, consisting of a 240 bp region 5′ of the tcpC gene, represents the major regulator of tcpC expression.

scholarly journals Complete Genome Sequence of Bacteriophage St11Ph5, Which Infects Uropathogenic Escherichia coli Strain up11

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Alla K. Golomidova ◽  
Eugene E. Kulikov ◽  
Vladislav V. Babenko ◽  
Elena S. Kostryukova ◽  
Andrey V. Letarov
Keyword(s):  
Escherichia Coli ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Host Strain ◽  
Host Recognition ◽  
Sewage Sample

ABSTRACT Bacteriophage St11Ph5 was isolated from a sewage sample on a particularly phage-resistant uropathogenic Escherichia coli (UPEC) up11 host strain. It appeared to be closely related to bacteriophage G7C, isolated from horse feces; however, it carries a highly divergent host recognition module.

scholarly journals Major Uropathogenic Escherichia coli Strain Isolated in the Northwest of England Identified by Multilocus Sequence Typing

2008 ◽  
Vol 46 (3) ◽  
pp. 1076-1080 ◽  
Author(s):  
S. H. Lau ◽  
S. Reddy ◽  
J. Cheesbrough ◽  
F. J. Bolton ◽  
G. Willshaw ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multilocus Sequence Typing ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli

scholarly journals Unusual Genotype of a Uropathogenic Escherichia coli Strain Assigned to the B2 Phylogenetic Group

2011 ◽  
Vol 49 (8) ◽  
pp. 3105-3106 ◽  
Author(s):  
N. Mendonca ◽  
V. Calhau ◽  
T. Lin ◽  
L. Boaventura ◽  
G. Ribeiro ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Phylogenetic Group

tRNA genes and pathogenicity islands: influence on virulence and metabolic properties of uropathogenic Escherichia coli

1995 ◽  
Vol 17 (1) ◽  
pp. 109-121 ◽  
Author(s):  
Angelika Ritter ◽  
Gabriele Blum ◽  
Levente Emödy ◽  
Monika Kerenyi ◽  
August Böck ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Uropathogenic Escherichia Coli ◽  
Pathogenicity Islands ◽  
Trna Genes ◽  
Metabolic Properties

scholarly journals Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

2016 ◽  
Vol 126 (7) ◽  
pp. 2425-2436 ◽  
Author(s):  
Anna Waldhuber ◽  
Manoj Puthia ◽  
Andreas Wieser ◽  
Christine Cirl ◽  
Susanne Dürr ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Nlrp3 Inflammasome ◽  
Coli Strain ◽  
Uropathogenic Escherichia Coli ◽  
Inflammasome Activation ◽  
Nlrp3 Inflammasome Activation ◽  
Strain Cft073
Sign in / Sign up

Export Citation Format

Share Document