P.131 Peripartum management of a patient with previous Ebola virus infection

2021 ◽  
Vol 46 ◽  
pp. 103129
Author(s):  
V. Thwaites ◽  
T. Murphy ◽  
E.C. Thomson
Keyword(s):  
Virus Infection ◽  
Ebola Virus ◽  
Ebola Virus Infection

scholarly journals Antibody-Dependent Enhancement of Ebola Virus Infection

2003 ◽  
Vol 77 (13) ◽  
pp. 7539-7544 ◽  
Author(s):  
Ayato Takada ◽  
Heinz Feldmann ◽  
Thomas G. Ksiazek ◽  
Yoshihiro Kawaoka
Keyword(s):  
Virus Infection ◽  
Ebola Virus ◽  
Human Populations ◽  
Hemorrhagic Disease ◽  
Viral Infectivity ◽  
Kidney Cells ◽  
Emerging Pathogens ◽  
Viral Glycoprotein ◽  
Antibody Dependent Enhancement ◽  
Ebola Virus Infection

ABSTRACT Most strains of Ebola virus cause a rapidly fatal hemorrhagic disease in humans, yet there are still no biologic explanations that adequately account for the extreme virulence of these emerging pathogens. Here we show that Ebola Zaire virus infection in humans induces antibodies that enhance viral infectivity. Plasma or serum from convalescing patients enhanced the infection of primate kidney cells by the Zaire virus, and this enhancement was mediated by antibodies to the viral glycoprotein and by complement component C1q. Our results suggest a novel mechanism of antibody-dependent enhancement of Ebola virus infection, one that would account for the dire outcome of Ebola outbreaks in human populations.

scholarly journals Loss of Interleukin 1 Receptor Antagonist Enhances Susceptibility to Ebola Virus Infection

2015 ◽  
Vol 212 (suppl 2) ◽  
pp. S329-S335 ◽  
Author(s):  
Lindsay Hill-Batorski ◽  
Peter Halfmann ◽  
Andrea Marzi ◽  
Tiago J. S. Lopes ◽  
Gabriele Neumann ◽  
...  
Keyword(s):  
Virus Infection ◽  
Receptor Antagonist ◽  
Ebola Virus ◽  
Interleukin 1 ◽  
Interleukin 1 Receptor Antagonist ◽  
Ebola Virus Infection

scholarly journals Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig

2020 ◽  
Vol 181 ◽  
pp. 104863 ◽  
Author(s):  
Thomas R. Lane ◽  
Christopher Massey ◽  
Jason E. Comer ◽  
Alexander N. Freiberg ◽  
Huanying Zhou ◽  
...  
Keyword(s):  
Virus Infection ◽  
Guinea Pig ◽  
Ebola Virus ◽  
Ebola Virus Infection

A Case of Severe Ebola Virus Infection Complicated by Gram-Negative Septicemia

2014 ◽  
Vol 371 (25) ◽  
pp. 2394-2401 ◽  
Author(s):  
Benno Kreuels ◽  
Dominic Wichmann ◽  
Petra Emmerich ◽  
Jonas Schmidt-Chanasit ◽  
Geraldine de Heer ◽  
...  
Keyword(s):  
Virus Infection ◽  
Ebola Virus ◽  
Gram Negative ◽  
Ebola Virus Infection

scholarly journals Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

2010 ◽  
Vol 4 (10) ◽  
pp. e837 ◽  
Author(s):  
Nadia Wauquier ◽  
Pierre Becquart ◽  
Cindy Padilla ◽  
Sylvain Baize ◽  
Eric M. Leroy
Keyword(s):  
Innate Immunity ◽  
Virus Infection ◽  
Ebola Virus ◽  
Lymphocyte Apoptosis ◽  
Ebola Virus Infection
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