Silk fibroin double-layer microneedles for the encapsulation and controlled release of triptorelin

Author(s):  
Xiaoyan Lu ◽  
Yiying Sun ◽  
Meishan Han ◽  
Daoyuan Chen ◽  
Aiping Wang ◽  
...  
2017 ◽  
Vol 5 (44) ◽  
pp. 8770-8779 ◽  
Author(s):  
Jiachen Sun ◽  
Yanxia Zhang ◽  
Bin Li ◽  
Yong Gu ◽  
Liang Chen

Controlled release of BMP-2 from a collagen-mimetic peptide-modified scaffold for bone regeneration.


RSC Advances ◽  
2017 ◽  
Vol 7 (89) ◽  
pp. 56550-56558 ◽  
Author(s):  
Huijun Li ◽  
Jingxin Zhu ◽  
Song Chen ◽  
Lan Jia ◽  
Yanlong Ma

This paper presents a new nanofabrication method for dual drug loaded regenerated silk fibroin (RSF) nanofibers, based on a simple, colloid-electrospinning technique.


2011 ◽  
Vol 12 (3) ◽  
pp. 804-812 ◽  
Author(s):  
Daniel J. Hines ◽  
David L. Kaplan

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Yaowalak Srisuwan ◽  
Yodthong Baimark

Silk fibroin (SF)/alginate blend films have been prepared for controlled release of tetracycline hydrochloride, an antimicrobial model drug. The blend films were analysed by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and UV-vis spectroscopy. The functional groups of the SF/alginate blends were monitored from their FTIR spectra. The homogeneity of the blend films was observed from SEM images. The dissolution and film transparency of the blend films depended on the SF/alginate blend ratio. Thein vitrodrug release profile of the blend films was determined by plotting the cumulative drug release versus time. It was found that the drug release significantly decreased as the SF/alginate blend ratio increased. The results demonstrated that the SF/alginate blend films should be a useful controlled-release delivery system for water-soluble drugs.


2014 ◽  
Vol 44 ◽  
pp. 166-174 ◽  
Author(s):  
Jing Qu ◽  
Yu Liu ◽  
Yanni Yu ◽  
Jing Li ◽  
Jingwan Luo ◽  
...  

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