Speech perception and cortical auditory evoked potentials in cochlear implant users with auditory neuropathy spectrum disorders

2012 ◽  
Vol 76 (9) ◽  
pp. 1332-1338 ◽  
Author(s):  
Kátia F. Alvarenga ◽  
Raquel Beltrão Amorim ◽  
Raquel Sampaio Agostinho-Pesse ◽  
Orozimbo Alves Costa ◽  
Leandra Tabanez Nascimento ◽  
...  
2007 ◽  
Vol 18 (05) ◽  
pp. 380-390 ◽  
Author(s):  
Wendy Pearce ◽  
Maryanne Golding ◽  
Harvey Dillon

Infants with auditory neuropathy and possible hearing impairment are being identified at very young ages through the implementation of hearing screening programs. The diagnosis is commonly based on evidence of normal cochlear function but abnormal brainstem function. This lack of normal brainstem function is highly problematic when prescribing amplification in young infants because prescriptive formulae require the input of hearing thresholds that are normally estimated from auditory brainstem responses to tonal stimuli. Without this information, there is great uncertainty surrounding the final fitting. Cortical auditory evoked potentials may, however, still be evident and reliably recorded to speech stimuli presented at conversational levels. The case studies of two infants are presented that demonstrate how these higher order electrophysiological responses may be utilized in the audiological management of some infants with auditory neuropathy. Los niños con neuropatía auditiva y posibles posibles trastornos auditivos están siendo identificados a edades tempranas con la implementación de programas de tamizaje auditivo. El diagnóstico se basa en la evidencia de una función coclear normal pero de una función anormal del tallo cerebral. Esta falta de función normal de tallo cerebral es muy problemática cuando se trata de prescribir amplificación en niños pequeños, porque las fórmulas de prescripción requieren el insumo de los umbrales auditivos que se estiman normalmente a partir de las respuestas del tallo cerebral ante estímulos tonales. Sin esta información, existe una gran incertidumbre en cuanto a la adaptación final. Los potenciales evocados auditivos corticales pueden, sin embargo, registrarse con confiabilidad a partir de estímulos de lenguaje presentados a niveles de intensidad para la conversación. Se presenta el estudio de dos casos de niños, que demuestran como estas respuestas electrofisiológicas de orden mayor pueden utilizarse en el manejo audiológico de algunos niños con neuropatía auditiva.


2020 ◽  
Vol 13 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Ji-Hye Han ◽  
Jihyun Lee ◽  
Hyo-Jeong Lee

Objectives. Cochlear implant (CI) users typically report impaired ability to understand speech in noise. Speech understanding in CI users decreases with noise due to reduced temporal processing ability, and speech perceptual errors involve stop consonants distinguished by voice onset time (VOT). The current study examined the effects of noise on various speech perception tests while at the same time used cortical auditory evoked potentials (CAEPs) to quantify the change of neural processing of speech sounds caused by noise. We hypothesized that the noise effects on VOT processing can be reflected in N1/P2 measures, the neural changes relate to behavioral speech perception performances.Methods. Ten adult CI users and 15 normal-hearing (NH) people participated in this study. CAEPs were recorded from 64 scalp electrodes in both quiet and noise (signal-to-noise ratio +5 dB) and in passive and active (requiring consonant discrimination) listening. Speech stimulus was synthesized consonant-vowels with VOTs of 0 and 50 ms. N1-P2 amplitudes and latencies were analyzed as a function of listening condition. For the active condition, the P3b also was analyzed. Behavioral measures included a variety of speech perception tasks.Results. For good performing CI users, performance in most speech test was lower in the presence of noise masking. N1 and P2 latencies became prolonged with noise masking. The P3b amplitudes were smaller in CI groups compared to NH. The degree of P2 latency change (0 vs. 50 ms VOT) was correlated with consonant perception in noise.Conclusion. The effects of noise masking on temporal processing can be reflected in cortical responses in CI users. N1/P2 latencies were more sensitive to noise masking than amplitude measures. Additionally, P2 responses appear to have a better relationship to speech perception in CI users compared to N1.


2015 ◽  
Vol 36 (6) ◽  
pp. 723-732 ◽  
Author(s):  
Carolyn J. Brown ◽  
Eun Kyung Jeon ◽  
Li-Kuei Chiou ◽  
Benjamin Kirby ◽  
Sue A. Karsten ◽  
...  

1998 ◽  
Vol 27 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Mohammad Jamal Makhdoum ◽  
Paul A.P. Groenen ◽  
Ad F.M. Snik ◽  
Paul van den Broek

2007 ◽  
Vol 18 (02) ◽  
pp. 126-140 ◽  
Author(s):  
Brett A. Martin

The purpose of this case study was to determine whether the P1-N1-P2 acoustic change complex (ACC) could be recorded in an individual with a cochlear implant. In a cochlear implant recipient, stimulus-related artifact from the implant can overlap the evoked potential of interest, making it difficult to determine whether the recorded response is neural or a simple reflection of the artifact. This is an even greater technical challenge for the ACC because stimuli having relatively long durations are used. The subject was a 24-year-old with a diagnosis of auditory neuropathy/auditory dys-synchrony and used a MED-EL Tempo+ cochlear implant in her left ear. The ACC was recorded to synthetic vowels containing a change of F2 at midpoint ranging from 0 (no change) to 1200 Hz (perceived as /ui/). The stimuli were presented randomly at 75 dB SPL via a loudspeaker. In one condition the subject ignored the stimuli and watched a captioned video. In the other, the subject pressed one button on a response pad if she perceived an acoustic change at stimulus midpoint and another if she did not. Cortical auditory evoked potentials were recorded from 32 scalp electrodes. Results indicated that the ACC was present and could be teased apart from the cochlear implant stimulus artifact. ACC thresholds showed good agreement with behavioral discrimination performance, and therefore, results are positive for the potential clinical application of the ACC technique to individuals with cochlear implants. El propósito de este estudio de caso fue determinar si el complejo de cambio acústico (ACC) P1-N2-P2 podía ser registrado en un individuo con un implante coclear. En un receptor de un implante coclear, los artefactos del implante relacionados con el estímulo se traslapan el potencial evocado de interés, haciendo difícil la determinación de si la respuesta registrada es neural o un simple reflejo del artefacto. Esto es un reto técnico aún más grande para los ACC porque se usan estímulos de relativa larga duración. El sujeto tenía 24 años con un diagnóstico de neuropatía/dis-sincronía auditiva, y utilizaba un implante coclear MED-EL Tempo+ en el oído izquierdo. El ACC se registró ante vocales sintéticas que contenían un cambio en el F2 a la mitad del rango entre 0 (sin cambio) a 1200 Hz (percibido como /ui/). El estímulo fue presentado al azar a 75 dB SPL por medio de parlantes. En una condición, el sujeto ignoró el estímulo y miró un video subtitulado. En la otra, el sujeto presionó un botón de respuesta si percibía un cambio acústico en el punto medio del estímulo y otro si no lo percibía. Se registraron los potenciales evocados auditivos corticales con 32 electrodos craneanos. Los resultados indicaron que el ACC estaba presente y podía ser separado de los artefactos del estímulo en el implante coclear. Los umbrales del ACC coincidieron con el desempeño en la discriminación conductual, y por lo tanto, los resultados son positivos para la aplicación clínica potencial de la técnica de ACC a individuos con implante coclear.


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