How did the Particle Therapy Grow in Japan? Current Status of Proton and Carbon Ion Radiation Therapy From 1979 to 2011 in Japan

2012 ◽  
Vol 84 (3) ◽  
pp. S661-S662
Author(s):  
Y. Ando ◽  
T. Kamada ◽  
N. Fuwa ◽  
T. Nakano ◽  
H. Sakurai ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Particle Therapy ◽  
Current Status ◽  
Carbon Ion

scholarly journals Clinical Limitations of Photon, Proton and Carbon Ion Therapy for Pancreatic Cancer

Cancers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 163 ◽  
Author(s):  
Mikaela Dell’Oro ◽  
Michala Short ◽  
Puthenparampil Wilson ◽  
Eva Bezak
Keyword(s):  
Pancreatic Cancer ◽  
Overall Survival ◽  
Radiation Therapy ◽  
Survival Rate ◽  
Particle Therapy ◽  
Current Status ◽  
Published Data ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Ion Therapy

Introduction: Despite improvements in radiation therapy, chemotherapy and surgical procedures over the last 30 years, pancreatic cancer 5-year survival rate remains at 9%. Reduced stroma permeability and heterogeneous blood supply to the tumour prevent chemoradiation from making a meaningful impact on overall survival. Hypoxia-activated prodrugs are the latest strategy to reintroduce oxygenation to radioresistant cells harbouring in pancreatic cancer. This paper reviews the current status of photon and particle radiation therapy for pancreatic cancer in combination with systemic therapies and hypoxia activators. Methods: The current effectiveness of management of pancreatic cancer was systematically evaluated from MEDLINE® database search in April 2019. Results: Limited published data suggest pancreatic cancer patients undergoing carbon ion therapy and proton therapy achieve a comparable median survival time (25.1 months and 25.6 months, respectively) and 1-year overall survival rate (84% and 77.8%). Inconsistencies in methodology, recording parameters and protocols have prevented the safety and technical aspects of particle therapy to be fully defined yet. Conclusion: There is an increasing requirement to tackle unmet clinical demands of pancreatic cancer, particularly the lack of synergistic therapies in the advancing space of radiation oncology.

Carbon ion radiation therapy for chordomas and low grade chondrosarcomas - current status of the clinical trials at GSI-

2004 ◽  
Vol 73 ◽  
pp. S53-S56 ◽  
Author(s):  
Daniela Schulz-Ertner ◽  
Anna Nikoghosyan ◽  
Bernd Didinger ◽  
Jürgen Debus
Keyword(s):  
Clinical Trials ◽  
Radiation Therapy ◽  
Current Status ◽  
Low Grade ◽  
Carbon Ion

scholarly journals Influence of dose-averaged linear energy transfer on tumour control after carbon-ion radiation therapy for pancreatic cancer

2020 ◽  
Vol 21 ◽  
pp. 19-24 ◽  
Author(s):  
Yasuhito Hagiwara ◽  
Tapesh Bhattacharyya ◽  
Naruhiro Matsufuji ◽  
Yuka Isozaki ◽  
Hirotoshi Takiyama ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Radiation Therapy ◽  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Carbon Ion ◽  
Tumour Control

Carbon-Ion Radiation Therapy for Pelvic Recurrence of Rectal Cancer

2016 ◽  
Vol 96 (1) ◽  
pp. 93-101 ◽  
Author(s):  
Shigeru Yamada ◽  
Tadashi Kamada ◽  
Daniel K. Ebner ◽  
Makoto Shinoto ◽  
Kotaro Terashima ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Radiation Therapy ◽  
Pelvic Recurrence ◽  
Carbon Ion ◽  
Recurrence Of Rectal Cancer

scholarly journals Radiation therapy for hepatocellular carcinoma: current status and perspectives from our experience

2011 ◽  
pp. 257-264
Author(s):  
Wei Jiang ◽  
Zhao-chong Zeng
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiation Therapy ◽  
Wide Spectrum ◽  
Distant Metastases ◽  
Current Status ◽  
Radiation Technology ◽  
Tumor Thrombosis ◽  
Liver Cancers ◽  
Advanced Stages ◽  
Promising Treatment

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is accompanied by a poor prognosis. We had reported that radiation therapy has great potential, in a wide spectrum of primary liver cancers, fromlocal advanced stage of the disease to the more advanced stages, with regional nodal metastases, tumor thrombosis, and for palliation of distant metastases. Following the initial observation that HCC is radiosensitive and with the development of radiation technology, radiotherapy has become a feasible and promising treatment modality for HCC, particularly for advanced forms of the disease. Here, we review the substantial amount of available data on radiotherapy for HCC, report on the current status of this application of radiotherapy, and propose future avenues of research.

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