pN0(i+) Breast Cancer: Treatment Patterns, Locoregional Recurrence, and Survival Outcomes

2013 ◽  
Vol 87 (4) ◽  
pp. 731-737 ◽  
Author(s):  
Irene Karam ◽  
Maria F. Lesperance ◽  
Tanya Berrang ◽  
Caroline Speers ◽  
Scott Tyldesley ◽  
...  
Author(s):  
Julia Frebault ◽  
Carmen Bergom ◽  
Chandler S. Cortina ◽  
Monica E. Shukla ◽  
Yiwen Zhang ◽  
...  

Author(s):  
Rui-Zhi Tang ◽  
Zhen-Zhen Liu ◽  
Saisai Gu ◽  
Xi-Qiu Liu

The locoregional recurrence of breast cancer after tumor resection represents several clinical challenges, and conventional post-surgical adjuvant therapeutics always bring with significant systemic side effects. Thus, the local therapy strategy...


2020 ◽  
Vol 8 (2) ◽  
pp. 224-232
Author(s):  
Asima Tayyeb

Therapies targeting estrogen receptor (ER) are being widely used to treat ER+ breast cancer patients. Despite early detection and improved survival outcomes, tamoxifen resistance, either intrinsic or acquired- is a major obstacle in effective disease management. Current review will summarize different molecular mechanisms of tamoxifen resistance both intrinsic and acquired in breast cancer treatment. This review not only provides basis to understand the nature of tamoxifen drug resistance but also suggests the mechanisms for its control leading to improved therapeutic interventions.


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