scholarly journals Phase 1b Trial of Superoxide (SO) Dismutase (SOD) Mimetic GC4419 to Reduce Chemoradiation Therapy (CRT)-Induced Oral Mucositis (OM) in Patients (pts) With Oral Cavity or Oropharyngeal Carcinoma (OCC)

2016 ◽  
Vol 96 (2) ◽  
pp. S83-S84 ◽  
Author(s):  
C.M. Anderson ◽  
B.G. Allen ◽  
W. Sun ◽  
S.S. Agarwala ◽  
C.M. Lee ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Oral Mucositis ◽  
Chemoradiation Therapy ◽  
Oropharyngeal Carcinoma ◽  
Phase 1B

scholarly journals Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma

2018 ◽  
Vol 100 (2) ◽  
pp. 427-435 ◽  
Author(s):  
Carryn M. Anderson ◽  
Stephen T. Sonis ◽  
Christopher M. Lee ◽  
Douglas Adkins ◽  
Bryan G. Allen ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Oral Cavity ◽  
Oral Mucositis ◽  
Oropharyngeal Carcinoma ◽  
Phase 1B

Phase Ib trial of superoxide (SO) dismutase (SOD) mimetic GC4419 to reduce chemoradiotherapy (CRT)-induced oral mucositis (OM) in patients (pts) with oral cavity or oropharyngeal carcinoma (OCC).

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 10120-10120 ◽  
Author(s):  
Carryn M. Anderson ◽  
Bryan G. Allen ◽  
Wenqing Sun ◽  
Sanjiv S. Agarwala ◽  
Christopher M. Lee ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Oral Mucositis ◽  
Oropharyngeal Carcinoma ◽  
Phase Ib

Methotrexate-induced oral mucositis in rheumatoid arthritis disease: Therapeutic strategy in a case report/Methotrexat-induzierte orale Mukositis bei rheumatoider Arthritis: Therapeutische Strategie in einem Fallbericht

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Margherita Gobbo ◽  
Giulia Ottaviani ◽  
Rossana Bussani ◽  
Gabriele Pozzato ◽  
Matteo Biasotto
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Oral Cavity ◽  
Oral Mucositis ◽  
Low Level Laser Therapy ◽  
Rheumatoid Arthritis Disease ◽  
Oral Pain ◽  
Relieve Pain ◽  
Level Laser

AbstractThe aim of this case report is to evaluate the efficacy of low-level laser therapy (LLLT) in the treatment of oral mucositis induced by methotrexate (MTX).A 52-year-old male patient, affected by rheumatoid arthritis and treated with corticosteroids and MTX, complained about severe oral pain and lesions for two months. He had been treated with topical and systemic corticosteroid therapy and chlorhexidine rinses with no significant improvement. He was not able to eat solid food or to wear his dental prosthesis. Examination of the oral cavity revealed retro-commissural and labial bilateral ulcerations and erythema and a 2-cm wide fibrous white lesion on the lower anterior vestibular ridge. Blood tests showed mild pancytopenia, and oral biopsies evidenced a “non-specific inflammatory condition” excluding any precancerous or paraneoplastic lesion or autoimmune diseases of the oral cavity. Previous medical records revealed that MTX had been discontinued many times due to mucositis since 2006, when the therapy had been started. This suggested a correlation between the onset of oral mucositis and MTX accumulation. LLLT was carried out for 4 consecutive days and three once-a-week follow-ups were performed.Lesions had completely healed during the second follow-up and the patient referred no pain at all from the 4th laser session on, therefore, the discontinuation of MTX had not been necessary.LLLT could represent an innovative technique to relieve pain related to MTX side effects thus avoiding dangerous discontinuation of therapy.

Relation of Lymph-Node Metastasis to Histopathologic Appearance in Oral Cavity and Oropharyngeal Carcinoma

1989 ◽  
Vol 99 (11) ◽  
pp. 1103???1110 ◽  
Author(s):  
Barry M. Rasgon ◽  
Raul M. Cruz ◽  
Raymond L. Hilsinger ◽  
John E. Sawicki
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cavity ◽  
Oropharyngeal Carcinoma ◽  
Node Metastasis

scholarly journals Variable course of progression of oral cavity and oropharyngeal carcinoma in young adults

2013 ◽  
Vol 3 ◽  
pp. 286-290
Author(s):  
Maciej Szczepan Pabiszczak ◽  
Elżbieta Waśniewska ◽  
Daniela Mielcarek-Kuchta ◽  
Dorota Miętkiewska-Leszniewska ◽  
Małgorzata Wierzbicka ◽  
...  
Keyword(s):  
Young Adults ◽  
Oral Cavity ◽  
Oropharyngeal Carcinoma

Selective intraarterial chemoradiation therapy for oropharyngeal carcinoma with high-dose cisplatin

2011 ◽  
Vol 29 (8) ◽  
pp. 570-575 ◽  
Author(s):  
Ryota Nishio ◽  
Kazuhiro Saito ◽  
Hiroyuki Ito ◽  
Tomoyuki Yoshida ◽  
Koichi Kitamura ◽  
...  
Keyword(s):  
Chemoradiation Therapy ◽  
Oropharyngeal Carcinoma ◽  
High Dose
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