scholarly journals Dose-Volume Correlates of Patient-Reported Trismus in Long-Term Oropharyngeal Cancer Survivors after IMRT

2018 ◽  
Vol 102 (3) ◽  
pp. S218
Author(s):  
M. Kamal ◽  
C. Rock ◽  
S.R. Grant ◽  
J. Zaveri ◽  
R. Granberry ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Dose Volume ◽  
Patient Reported

Determinants of patient‐reported xerostomia among long‐term oropharyngeal cancer survivors

Cancer ◽  
2021 ◽  
Author(s):  
Puja Aggarwal ◽  
Katherine A. Hutcheson ◽  
Adam S. Garden ◽  
Frank E. Mott ◽  
Charles Lu ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Patient Reported

scholarly journals Single‐item discrimination of quality‐of‐life–altering dysphagia among 714 long‐term oropharyngeal cancer survivors: Comparison of patient‐reported outcome measures of swallowing

Cancer ◽  
2019 ◽  
Vol 125 (10) ◽  
pp. 1654-1664 ◽  
Author(s):  
◽  
Stephen Grant ◽  
Mona Kamal ◽  
Abdallah S. R. Mohamed ◽  
Jhankruti Zaveri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Outcome Measures ◽  
Oropharyngeal Cancer ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Single Item ◽  
Patient Reported

scholarly journals Determinants of Cancer-specific Quality of Life in Veteran Lung Cancer Survivors Eligible for Long-Term Cure

2019 ◽  
Author(s):  
Duc Ha ◽  
Andrew L. Ries ◽  
Jeffrey J. Swigris
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Survivors ◽  
Summary Score ◽  
European Organization ◽  
Specific Patient ◽  
Patient Reported ◽  
Sleep Difficulties

AbstractRationale/ObjectiveQuality of life (QoL) is an important issue in lung cancer survivors. We aimed to identify determinants of QoL in lung cancer survivors eligible for long-term cure.MethodsWe performed an exploratory analysis of a cross-sectional study of consecutive lung cancer survivors who completed curative-intent treatment ≥1 month previously. Variables tested included demographic, clinical, physiologic, and symptom-specific patient-reported outcome measures. We defined the primary outcome as a previously-validated cancer-specific QoL measure – the European Organization for Research and Treatment of Cancer QoL Questionnaire Core 30 (C30) summary score. We also verified our findings with the C30 global health status/QoL subscale and a summated score of lung cancer-specific QoL from the EORTC-Lung Cancer Module 13.ResultsIn 75 enrolled participants, measures of fatigue, depression, sleep difficulties, and dyspnea were statistically significant determinants of the C30 summary score in multivariable linear regression analyses. Together, these four symptoms accounted for approximately 85% of the variance in cancer-specific QoL (p<0.001). When we verified our findings with global QoL and lung cancer-specific QoL, fatigue and dyspnea were consistent determinants of QoL.ConclusionsWe found four symptoms – dyspnea, fatigue, depression, and sleep difficulties – that are important determinants of and together accounted for almost all of the variance in cancer-specific QoL in lung cancer survivors eligible for long-term cure. These findings have implications to reduce symptom burden and improve function and QoL in these patients.

scholarly journals Correction to: Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: cross-sectional assessment of a prospective symptom survey in patients ≥65 years old

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Salman A. Eraj ◽  
◽  
Mona K. Jomaa ◽  
Crosby D. Rock ◽  
Abdallah S. R. Mohamed ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Oropharyngeal Cancer ◽  
Patient Reported Outcomes ◽  
Cross Sectional ◽  
Patient Reported

scholarly journals The impact of tongue-deviating and tongue-depressing oral stents on long-term radiation-associated symptoms in oropharyngeal cancer survivors

2020 ◽  
Vol 24 ◽  
pp. 71-78 ◽  
Author(s):  
Sonja Stieb ◽  
Ismael Perez-Martinez ◽  
Abdallah S.R. Mohamed ◽  
Stockton Rock ◽  
Nimit Bajaj ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Associated Symptoms ◽  
The Impact

Long-term patient reported outcomes following radiation therapy for oropharyngeal cancer: A symptom assessment study in patients >65 years old.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21611-e21611 ◽  
Author(s):  
Salman Ali Eraj ◽  
Mona K Jomaa ◽  
Crosby Douglas Rock ◽  
Abdallah Mohamed ◽  
Adam S. Garden ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Head And Neck ◽  
Oropharyngeal Cancer ◽  
Symptom Burden ◽  
Symptom Assessment ◽  
Distinct Pattern ◽  
Assessment Tools ◽  
Dry Mouth ◽  
Patient Reported

e21611 Background: Given the potential for older patients (pts) to experience exaggerated toxicity and symptoms, this study was performed to characterize pt reported outcomes (PROs) in older pts following definitive radiation therapy (RT) for oropharyngeal cancer (OPC). Methods: Disease-free head and neck cancer survivors ( > 6 mos. since tx) were eligible for participation in a questionnaire-based study. Participants completed the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN). Those who had been treated for OPC with definitive RT (w/ or w/o systemic therapy) and were > 65 y/o at time of RT were included. Individual and overall symptom severity and clinical variables were analyzed. Results: Of the 79 participants analyzed, 82% were male, 95% white, 41% T3/4 disease, 39% RT alone, 27% induction chemotherapy, 52% concurrent, and 18% both, and 96% IMRT. Median age at the time of RT was 71 yrs. (range: 65-85); median time from end of RT to MDASI-HN completion was 46 mos. (2/3 > 24 mos.). The top 5 MDASI-HN items rated most severe in terms of mean (±SD) ratings (0-10 scale) were dry mouth (3.48±2.95), taste (2.81±3.29), swallowing (2.59±2.96), mucus in mouth/throat (2.04±2.68), and choking (1.30±2.38) reported at moderate to severe levels (≥5) by 35, 29, 29, 18, and 13%, respectively. Thirty-nine % reported none (0) or no more than mild (1-4) symptoms across all 22 MDASI-HN symptoms items, and 38% had at least one item rated as severe (≥7). Hierarchal cluster analysis resulted in 3 patient groups: 1) ~75% with generally no to moderate symptom burden, 2) ~25% with moderate to severe ratings for a subset of classically RT-related symptoms (e.g. dry mouth, mucus, swallow, taste), and 3) only 2 pts with severe ratings of nearly all items. Subgroup comparisons will be presented. Conclusions: The overall long-term symptom burden seen in this older OPC cohort was largely favorable, yet a higher symptom group (~25%) with a distinct pattern of mostly local symptoms was identified. We have implemented the routine use of symptom assessment tools as part of OPC survivorship programs and plan to explore age-dose-modeling of symptoms identified and associated normal structures.

scholarly journals Association of Risk Factors With Patient-Reported Voice and Speech Symptoms Among Long-term Survivors of Oropharyngeal Cancer

2021 ◽  
Author(s):  
Puja Aggarwal ◽  
Katherine A. Hutcheson ◽  
Adam S. Garden ◽  
Frank E. Mott ◽  
Ryan P. Goepfert ◽  
...  
Keyword(s):  
Risk Factors ◽  
Oropharyngeal Cancer ◽  
Patient Reported ◽  
Long Term Survivors ◽  
Voice And Speech

scholarly journals Functional Burden Associated with Late Lower Cranial Neuropathy in Long-Term Oropharyngeal Cancer Survivors Treated with Definitive Radiation Therapy

2018 ◽  
Vol 102 (3) ◽  
pp. e408
Author(s):  
P. Aggarwal ◽  
J. Zaveri ◽  
R.P. Goepfert ◽  
G.B. Gunn ◽  
S. Lai ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Cranial Neuropathy

scholarly journals Symptom Burden Associated With Late Lower Cranial Neuropathy in Long-term Oropharyngeal Cancer Survivors

2018 ◽  
Vol 144 (11) ◽  
pp. 1066 ◽  
Author(s):  
Puja Aggarwal ◽  
Jhankruti S. Zaveri ◽  
Ryan P. Goepfert ◽  
Qiuling Shi ◽  
Xianglin L. Du ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Symptom Burden ◽  
Cranial Neuropathy

Late radiation-associated dysphagia with lower cranial neuropathy in long-term oropharyngeal cancer survivors: Video case reports

Head & Neck ◽  
2015 ◽  
Vol 37 (4) ◽  
pp. E56-E62 ◽  
Author(s):  
Katherine A. Hutcheson ◽  
Margaret M. Yuk ◽  
F. Christopher Holsinger ◽  
G. Brandon Gunn ◽  
Jan S. Lewin
Keyword(s):  
Cancer Survivors ◽  
Oropharyngeal Cancer ◽  
Case Reports ◽  
Cranial Neuropathy
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