In Patients with Lateralized Oral Cavity and Oropharynx Squamous Cell Carcinoma with N2b Disease, Is It Safe to Omit Radiotherapy to the contralateral clinical N0 Neck?

2020 ◽  
Vol 106 (5) ◽  
pp. 1145
Author(s):  
J.D. Gruhl ◽  
A.M. Torgeson ◽  
K. McComas ◽  
M. Monroe ◽  
Y.J. Hitchcock
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
N0 Neck ◽  
Oropharynx Squamous Cell Carcinoma

Radionecrosis after Treating Oral Cavity & Oropharyngeal SCC

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P43-P44
Author(s):  
Sundip H Patel ◽  
Mike Yao ◽  
Tara Brennan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Care Facility ◽  
Tertiary Care Facility ◽  
Pertinent Data ◽  
Associated Risk Factors ◽  
Oropharynx Squamous Cell Carcinoma

Objective 1) The primary goal of this study was to evaluate the incidence of radionecrosis among patients treated with radiation therapy for oral cavity & oropharynx squamous cell carcinoma at our institution. Many patients with oral cavity & oropharyngeal cancers receive radiation to preserve the tongue, knowing the risks of post-treatment radionecrosis. However, recent protocols have intensified chemo-radiotherapy in an effort to improve local control while possibly increasing risk. 2) Among those patients with radionecrosis, we also analyzed their cancer treatment regimen, associated risk factors, the severity of the radionecrosis and the resulting treatment they recieved. Methods We performed a retrospective review of all adult patients at our tertiary care facility with biopsy proven squamous cell carcinoma of the oral cavity & oropharynx from 1999 to 2007 who completed a full course of radiotherapy at our facility with at least 6 months follow-up. Medical charts were reviewed for the presence of radionecrosis as well as for other corresponding, pertinent data. Results After reviewing 241 patients, a total of 107 patients were included. 5 of 65 with oropharynx disease had radionecrosis, revealing an incidence of 7.7%. Among the oral cavity group there were 8 out of 42 patients with radionecrosis, revealing an incidence of 19%. The overall incidence among our treatment group was 12.1%. Conclusions Radiation-induced necrosis of the oral cavity & oropharynx is still a significant complication in the treatment of head and neck cancer and poses a higher risk in the oral cavity than the oropharynx.

Expression of stem cell-regulating miRNAs in oral cavity and oropharynx squamous cell carcinoma

2016 ◽  
Vol 45 (9) ◽  
pp. 647-654 ◽  
Author(s):  
Bárbara de Lima Brito ◽  
Silvia Vanessa Lourenço ◽  
Aline Santos Damascena ◽  
Luiz Paulo Kowalski ◽  
Fernando Augusto Soares ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

scholarly journals Impact of Perineural Invasion in the Pathologically N0 Neck in Oral Cavity Squamous Cell Carcinoma

2013 ◽  
Vol 149 (6) ◽  
pp. 893-899 ◽  
Author(s):  
Steven B. Chinn ◽  
Matthew E. Spector ◽  
Emily L. Bellile ◽  
Jonathan B. McHugh ◽  
Thomas J. Gernon ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Perineural Invasion ◽  
N0 Neck

Composite resection with mandibulectomy in the treatment of posterolateral oral cavity and lateral oropharynx squamous cell carcinoma

1993 ◽  
Vol 166 (4) ◽  
pp. 435-439 ◽  
Author(s):  
Jean-Louis Lefebvre ◽  
Bernard Vankemmel ◽  
Bernard Prevost ◽  
Etienne Buisset ◽  
Bernard Coche-Dequeant ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

scholarly journals Study of microscopic neck metastasis in clinically N0 neck in oral squamous cell carcinoma

2021 ◽  
Vol 43 (3) ◽  
pp. 293-299
Author(s):  
Nikzad Shahidi ◽  
Nastaran Zokaei
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Significant Relationship ◽  
Cervical Lymph Nodes ◽  
Metastatic Lymph Nodes ◽  
N0 Neck ◽  
Metastatic Lymph

Background: Metastasis of aerodigestive tract cancers to cervical lymph nodes is one of the otolaryngologists’ concerns that relies on a variety of factors such as the size of the primary tumor and its spread. We aimed to study the prevalence of occult cervical metastases in patients with clinical N0 neck in oral cavity squamous cell carcinoma. Methods: In this cross-sectional analytic study, the researchers referred to the archive of Emam Reza Hospital and studied medical files of patients with a definite diagnosis of oral cavity squamous cell carcinoma admitted from April 2011 to April 2016 while collecting relevant data such as age, gender, size of the primary mass, place of the lesion, clinical and pathological nodal involvement. The data was analyzed employing SPSS 19 whereas the statistical significance level in all exams was set at 0.05. Results: Average age of participants was 61.67 ± 14.02, and they were mostly male. Forty-five percent of participants had a clinical N0 neck and the majority of them didn’t have metastasis in the pathological study. The prevalence of metastatic lymph nodes in patients with clinical N0 was 30%. No significant relationship was observed between the number of lymph nodes containing occult metastasis and T of the tumor (P = .578). Conclusion: In squamous cell carcinoma of oral cavity, the prevalence of metastatic lymph nodes in the neck is 30% and is significantly related to the location of the lesion while no significant relationship to T of the tumor is observed.

Sentinel lymph node biopsy for management of the N0 neck in oral cavity squamous cell carcinoma

2019 ◽  
Author(s):  
John T. Loree ◽  
Saurin R. Popat ◽  
Mark S. Burke ◽  
Jennifer Frustino ◽  
Jeewanjot S. Grewal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymph Node Biopsy ◽  
N0 Neck ◽  
Node Biopsy
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