Radionecrosis after Treating Oral Cavity & Oropharyngeal SCC

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P43-P44
Author(s):  
Sundip H Patel ◽  
Mike Yao ◽  
Tara Brennan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Care Facility ◽  
Tertiary Care Facility ◽  
Pertinent Data ◽  
Associated Risk Factors ◽  
Oropharynx Squamous Cell Carcinoma

Objective 1) The primary goal of this study was to evaluate the incidence of radionecrosis among patients treated with radiation therapy for oral cavity & oropharynx squamous cell carcinoma at our institution. Many patients with oral cavity & oropharyngeal cancers receive radiation to preserve the tongue, knowing the risks of post-treatment radionecrosis. However, recent protocols have intensified chemo-radiotherapy in an effort to improve local control while possibly increasing risk. 2) Among those patients with radionecrosis, we also analyzed their cancer treatment regimen, associated risk factors, the severity of the radionecrosis and the resulting treatment they recieved. Methods We performed a retrospective review of all adult patients at our tertiary care facility with biopsy proven squamous cell carcinoma of the oral cavity & oropharynx from 1999 to 2007 who completed a full course of radiotherapy at our facility with at least 6 months follow-up. Medical charts were reviewed for the presence of radionecrosis as well as for other corresponding, pertinent data. Results After reviewing 241 patients, a total of 107 patients were included. 5 of 65 with oropharynx disease had radionecrosis, revealing an incidence of 7.7%. Among the oral cavity group there were 8 out of 42 patients with radionecrosis, revealing an incidence of 19%. The overall incidence among our treatment group was 12.1%. Conclusions Radiation-induced necrosis of the oral cavity & oropharynx is still a significant complication in the treatment of head and neck cancer and poses a higher risk in the oral cavity than the oropharynx.

Histopathological spectrum of oral cavity lesions – A tertiary care experience

2021 ◽  
Vol 8 (3) ◽  
pp. 364-368
Author(s):  
Ishani Gupta ◽  
Rekha Rani ◽  
Jyotsna Suri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Retrospective Study ◽  
Oral Cancer ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Proper Management ◽  
The World ◽  
One Year

Oral cancer is one of a major health problem in some parts of the world especially in the developing countries. Oral cancer is the sixth most common cancer in the world whereas in India it is one of the most prevalent cancer. Oral cavity lesions are usually asymptomatic. Accurate diagnosis of the lesion is the first step for the proper management of patients and histopathology is considered as the gold standard. The objective is to study the different patterns of oral cavity lesions seen in a tertiary care hospital of Jammu: One year retrospective study. Post graduate department of pathology.: It was a retrospective study carried out in a tertiary care centre for a period of one year from March 2020 to Feb 2021. 148 cases of oral cavity lesions were included in this study. The parameters that were included in the study were sociodemographic data, site of the lesion, clinical features and histological diagnosis. Data collected was analysed.148 cases of oral lesions were identified during the period of study. The age of patients varied from 5 to 78years and Male to Female ratio was 2.2:1. Buccal mucosa (30%) was the most common site involved which was followed by tonsil (19%). Out of 148 cases 70 cases were malignant, 10 cases pre malignant and 21 cases were benign. Squamous cell carcinoma (33.7%) was the most common lesion present in our study. Oral cavity lesions have a vast spectrum of diseases which range from tumour like lesions to benign and malignant tumours. Our study concluded that squamous cell carcinoma was the most common malignant lesion of oral cavity. Histological typing of the lesion is important for confirmation of malignancy and it is essential for the proper management of the patient.

Expression of stem cell-regulating miRNAs in oral cavity and oropharynx squamous cell carcinoma

2016 ◽  
Vol 45 (9) ◽  
pp. 647-654 ◽  
Author(s):  
Bárbara de Lima Brito ◽  
Silvia Vanessa Lourenço ◽  
Aline Santos Damascena ◽  
Luiz Paulo Kowalski ◽  
Fernando Augusto Soares ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

Composite resection with mandibulectomy in the treatment of posterolateral oral cavity and lateral oropharynx squamous cell carcinoma

1993 ◽  
Vol 166 (4) ◽  
pp. 435-439 ◽  
Author(s):  
Jean-Louis Lefebvre ◽  
Bernard Vankemmel ◽  
Bernard Prevost ◽  
Etienne Buisset ◽  
Bernard Coche-Dequeant ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

scholarly journals EP-1023: Challenges in treatment of oral cavity squamous cell carcinoma in a tertiary care centre in India

2013 ◽  
Vol 106 ◽  
pp. S392
Author(s):  
S. Chatterjee ◽  
S. Sarkar ◽  
B. Bang ◽  
R. Sharan ◽  
A. Pattatheyil ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre

scholarly journals A Study on Malignancy of Oral Cavity Cases Presenting to a Tertiary Care Centre in Western Odisha

2021 ◽  
Vol 8 (13) ◽  
pp. 764-767
Author(s):  
Satyajit Mishra ◽  
Dipti Ranjan Patjoshi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Mouth Opening ◽  
Cervical Lymphadenopathy ◽  
Common Disease ◽  
Predisposing Factor ◽  
Chewing Tobacco

BACKGROUND Malignancy of oral cavity is quite a common disease entity in Western part of the state of Odisha. This is because of prevalence of habits like smoking, chewing tobacco, and consumption of alcohol. Ignorance about the severity of the condition in early stages leads to delayed diagnosis. METHODS A study was undertaken in Bhima Bhoi Medical College, Bolangir, in Western Orissa from October 2018 to September 2020 to study about different patterns of presentations and histopathological variations of malignancy of oral cavity in this part of Odisha. Patients were thoroughly clinically evaluated, examined, and appropriate investigation protocol was followed to record data. RESULTS About 0.33 % of all patients coming to the outpatient department (OPD) were found to be suffering from carcinoma of oral cavity. Maximum number of cases were males in the 5th and 6th decade with squamous cell carcinoma. Predisposing factors like areca nut and pan masala consumption were noted. A majority of patients were cultivators from lower middle-class families. Other common groups were businessman and industrial workers. They had come with burning sensation in the mouth and restricted mouth opening as complaints. Xerostomia, fibrous bands in mouth, cervical lymphadenopathy were signs that were detected. Cheek was seen to be a primary site of lesion in large number of cases followed by tongue and lip. CONCLUSIONS In spite of them being easily assessable, patients ignored their symptoms leading to delay in reporting to healthcare facility. As the patients were from disadvantaged background, by the time they came to hospital, they were in an advanced stage (stage three). Squamous cell carcinoma is very common in this part of Orissa. Proper guidance to the patients about the symptoms and risk factors will go a long way in early diagnosis and a more favourable outcome post treatment. KEYWORDS Malignancy, Oral Cavity, Predisposing Factor, Stage

Clinico-pathological Spectrum of Oral Cavity Lesions at a Tertiary Care Center in Central Nepal: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Shankar Bastakoti ◽  
Gambhir Shrestha ◽  
Dej Kumar Gautam ◽  
Ishan Dhungana ◽  
Nandita Jha ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Malignant Lesion ◽  
Female Ratio ◽  
Central Nepal ◽  
Common Cancer ◽  
Malignant Lesions

Introduction: Head and neck cancer is the sixth most common cancer in the world. The disease burden is increasing at an alarming rate in developing Southeast Asian countries. This study aims to report the histopathological spectrum of oral cavity lesions at a tertiary cancer center in central Nepal. Methods: This study included all those cases of oral cavity lesions, of which diagnostic biopsy was done from January 2018 to December 2019. The data were retrieved from the Department of Pathology of BP Koirala Memorial Cancer Hospital. The study proposal was approved by the Institutional Review Committee at BPKMCH (Ref: 247/2020) on 28th June 2020. Results: A total of 851 cases of oral cavity lesions were included in this study. The mean age of the study population was 55.9 years, with male to female ratio of 3:1. Malignant lesions composed of 472 (55.5%) cases followed by premalignant lesion of 104 (12%). More than 453 (95%) malignant cases were squamous cell carcinoma, of which 342 (75%) were a well-differentiated type. The buccal cavity is the most common site of malignant lesion 212 (45%), followed by tongue 96 (20%) and lower gingivobuccal region 86 (18%). Conclusions: Malignant lesions are the most common histopathological fi ndings in the oral cavity lesion with squamous cell carcinoma type. Oral cancer is common cancer that can be prevented and cured if detected early.

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