Radiotherapy Remains Underutilized in the Treatment of Soft-Tissue Sarcomas: Disparities in Practice Patterns in the United States

2020 ◽  
Vol 108 (2) ◽  
pp. E59-E60
Author(s):  
Jacob Shabason ◽  
Vishruth Reddy ◽  
Varsha Jain ◽  
Sriram Venigalla ◽  
William Levin ◽  
...  
Keyword(s):  
United States ◽  
Soft Tissue ◽  
Practice Patterns ◽  
Soft Tissue Sarcomas ◽  
The United States

scholarly journals Soft Tissue Sarcoma Guidelines

2007 ◽  
Vol 5 (4) ◽  
pp. 364 ◽  
Author(s):  
_ _
Keyword(s):  
United States ◽  
Soft Tissue ◽  
Mortality Rate ◽  
Soft Tissue Sarcoma ◽  
Single Agent ◽  
Soft Tissue Sarcomas ◽  
The United States ◽  
Desmoid Tumors ◽  
Recent Version ◽  
Overall Mortality

Soft tissue sarcomas are the most frequent sarcomas; the annual incidence for 2007 in the United States is estimated at about 9220 cases, with an overall mortality rate of approximately 3560 cases per year. Important updates for the 2007 version of the guidelines include the addition of epirubicin (single agent) and the combination of epirubicin, ifosfamide, and mesna as generally accepted systemic therapy. Imatinib was added as an option for desmoid tumors. For the most recent version of the guidelines, please visit NCCN.org

scholarly journals Trends in the incidence of soft tissue sarcomas in the United States from 1973 through 1987

Cancer ◽  
1993 ◽  
Vol 72 (2) ◽  
pp. 486-490 ◽  
Author(s):  
Julie A. Ross ◽  
Richard K. Severson ◽  
Scott Davis ◽  
John J. Brooks
Keyword(s):  
United States ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
The United States

scholarly journals Treatment patterns and survival among older adults in the United States with advanced soft-tissue sarcomas

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Rohan C. Parikh ◽  
Maria Lorenzo ◽  
Lisa M. Hess ◽  
Sean D. Candrilli ◽  
Steven Nicol ◽  
...  
Keyword(s):  
United States ◽  
Older Adults ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
The United States ◽  
Treatment Patterns

scholarly journals Radiotherapy Remains Underused in the Treatment of Soft-Tissue Sarcomas: Disparities in Practice Patterns in the United States

2021 ◽  
Vol 19 (3) ◽  
pp. 295-306
Author(s):  
Vishruth K. Reddy ◽  
Varsha Jain ◽  
Sriram Venigalla ◽  
William P. Levin ◽  
Robert J. Wilson ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tumor Size ◽  
Practice Patterns ◽  
Insurance Coverage ◽  
Soft Tissue Sarcomas ◽  
The United States ◽  
Factors Associated ◽  
Number Of Patients ◽  
Over Time ◽  
Relevant Factors

Background: Practice patterns of radiation therapy (RT) use for soft-tissue sarcoma (STS) remain quite variable, despite clinical practice guidelines recommending the addition of RT to surgery for patients with high-grade STS, particularly for larger tumors. Using the National Cancer Database (NCDB), we assessed patterns of overall RT use, neoadjuvant versus adjuvant treatment, and specific RT modalities in this population. Patients and Methods: Patients aged ≥18 years with stage II/III STS in 2004 through 2015 were identified from the NCDB. Patterns of care were assessed using multivariable logistic regression analysis. Results: Of 27,426 total patients, 11,654 (42%) were treated with surgery alone versus 15,772 (58%) with RT in addition to surgery, with no overall increase in RT use over the study period. Notable clinical predictors of receipt of RT included tumor size (>5 cm), grade III, and tumors arising in the extremities. Conversely, female sex, older age (≥70 years), Black race, noncommercial insurance coverage, farther distance to treatment, and poor performance status were negative predictors of RT use. Of those receiving RT, 27% were treated with neoadjuvant RT and 73% with adjuvant RT. The proportion of those receiving neoadjuvant RT increased over time. Relevant factors associated with neoadjuvant RT included treatment at academic centers, larger tumor size, and extremity tumors. Of those who received RT with a modality specified as either intensity-modulated RT (IMRT) or 3D conformal RT (3DCRT), 61% were treated with IMRT and 39% with 3DCRT. The proportion of patients treated with IMRT increased over time. Relevant factors associated with IMRT use included treatment at academic centers, commercial insurance coverage, and larger and nonextremity tumors. Conclusions: Although use of neoadjuvant RT and IMRT has increased over time, a significant number of patients with STS are not receiving adjuvant or neoadjuvant RT. Our findings also note potential sociodemographic disparities and highlight the concern that not all patients with STS are being equally considered for RT.

Current practice patterns for management of vulvodynia in the United States

2016 ◽  
Vol 295 (3) ◽  
pp. 669-674 ◽  
Author(s):  
Lannah L. Lua ◽  
Yvette Hollette ◽  
Prathamesh Parm ◽  
Gayle Allenback ◽  
Vani Dandolu
Keyword(s):  
United States ◽  
Current Practice ◽  
Practice Patterns ◽  
The United States

Multi-practice survey on MR imaging practice patterns in rectal cancer in the United States

2021 ◽  
Author(s):  
David D. B. Bates ◽  
Hiram Shaish ◽  
Marc J. Gollub ◽  
Mukesh Harisinghani ◽  
Chandana Lall ◽  
...  
Keyword(s):  
United States ◽  
Rectal Cancer ◽  
Mr Imaging ◽  
Practice Patterns ◽  
The United States ◽  
Practice Survey
Sign in / Sign up

Export Citation Format

Share Document