scholarly journals Volumetric Modulated Arc Therapy Versus Three-Dimensional Conformal Radiotherapy for Breast Cancer Patients Treated with Regional Nodal Irradiation

2020 ◽  
Vol 108 (3) ◽  
pp. e63-e64
Author(s):  
M. Ogita ◽  
Y. Nozawa ◽  
K. Nawa ◽  
H. Yamashita ◽  
K. Nakagawa
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Conformal Radiotherapy ◽  
Breast Cancer Patients ◽  
Regional Nodal Irradiation ◽  
Arc Therapy ◽  
Three Dimensional Conformal Radiotherapy

scholarly journals Dosimetric comparison of Volumetric Modulated Arc Therapy and Three-Dimensional Conformal Radiotherapy during Post Mastectomy left chest wall Irradiation

2017 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Breast Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Left Lung ◽  
Conformal Radiotherapy ◽  
Breast Cancer Patients ◽  
Arc Therapy ◽  
Three Dimensional Conformal Radiotherapy ◽  
Higher Doses ◽  
3D Crt

Aims: To dosimetrically evaluate the Volumetric Modulated Arc Therapy (VMAT) technique and compare it with Three-Dimensional Conformal Radiotherapy (3D-CRT) for postmastectomy breast cancer therapy. Methods and Material: Ten consecutively treated left sided breast cancer patients were selected for this study. VMAT plans were generated from each of the patients planning CT and compared with 3D-CRT plans. Statistical analysis used: Two tailed paired t test Results: The VMAT technique provided statistically significant homogenous and conformal dose distribution with mean HI of (0.1±0.02) and mean CI of (1.1±0.06) when compared mean HI of (0.3±0.02) and mean CI of (1.7±0.2) in the 3D-CRT technique. VMAT plans showed reduced V30 of the heart (10±4.54) when compared to 3D-CRT plans (15.1±8.53). Except V30, VMAT plans resulted in higher doses to heart. The mean doses received by left lung was (17.50±6.27) and was significantly higher than that of 3D-CRT plans (10.20±3.72). VMAT plans also gave higher doses to the contralateral lung and the opposite breast. Conclusions: VMAT plans in post mastectomy breast cancers provide more homogenous and conformal plans as compared to 3DCRT plans but higher doses to normal tissues.

Dosimetric analysis of intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for chest wall irradiation in breast cancer patients

2015 ◽  
Vol 15 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Mehlam Kausar ◽  
Om Prakash Gurjar ◽  
Priyusha Bagdare ◽  
Krishna Lal Gupta ◽  
Virendra Bhandari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Chest Wall ◽  
Three Dimensional ◽  
Intensity Modulated Radiotherapy ◽  
Conformal Radiotherapy ◽  
Breast Cancer Patients ◽  
Intensity Modulated ◽  
Significant Difference ◽  
Three Dimensional Conformal Radiotherapy

AbstractBackgroundFor chest wall irradiation in breast cancer patients, three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) have made tremendous changes in treatment delivery.PurposeThe purpose of this study is to compare the dosimetric parameters in IMRT and 3DCRT plans.Materials and methodsIMRT and 3DCRT plans were generated for 25 randomly selected postmastectomy breast cancer patients. The prescribed dose (PD) was 50 Gray (Gy) in 25 fractions (#) at the rate of 2 Gy/# with 5#/week. Dose volume histogram was evaluated for planning target volume (PTV) coverage and dose to organs at risk (OARs). All the dosimetric parameters were compared using unpaired student’s t-test.ResultsPTV coverage was significantly better in IMRT, although the 90% of PTV was well covered by 90% of PD in all plans by both the techniques. Homogeneity index and conformity index were better in IMRT. V5 Gy and Dmean of contralateral lung, contralateral breast and heart (right side chest wall cases) were found to be lesser in 3DCRT compared with that in IMRT. However, there was no significant difference in V20 Gy of ipsilateral lung and V25 Gy of heart (left side chest wall cases) in all the plans by both the techniques.ConclusionAdequate target coverage was achieved by both the techniques, however, dose to OARs were lesser in 3DCRT plans as compared with that in IMRT plans. Thus, it can be concluded that 3DCRT is as efficient as IMRT for the chest wall irradiation.

scholarly journals So sánh các thông số liều lượng của kỹ thuật vmat và 3d-crt trong xạ trị ung thư vú trái và hạch vùng

2020 ◽  
Author(s):  
Đình Long Nguyễn
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Left Lung ◽  
Conformal Radiotherapy ◽  
Left Breast ◽  
Three Dimension ◽  
Breast Cancer Patients ◽  
Arc Therapy ◽  
3D Crt

COMPARISON OF DOSIMETRIC PARAMETERS OF VOLUMETRIC MODULATED ARC THERAPY AND THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY FOR LEFT SIDE BREAST AND REGIONAL NODES Objective: Comparative study of dose parameters of Volumetric modulated arc therapy (VMAT) and three-dimension radiotherapy (3D-CRT) in patients after left breast surgery with radiation therapy with regional lymph nodes. Materials and Methods: Twenty-four plans of 12 left-breast cancer patients were treated with VMAT with 4 partial arc and 3D-CRT plans were added to compare each other, from 1/2018 to 3/2019 at the Vinmec TimesCity International Hospital. Results: The average coverage dose to the treatment volume (PTV) of VMAT plans is better than the 3D-CRT plan (99.10 ± 0.17 % compared to 98.7 ± 0.34 %; p = 0.01). Conformity index (CI), homogeneity index (HI) for VMAT plans also better results CI: 0.99 vs. 0.98; p = 0.26 and HI: 0.096 compared to 0.119; p = 0.02). Organs at risk, at low doses V5Gy, V10Gy VMAT plans do not avoid good doses by 3D-CRT plans: V5Gy for left lung (78.8 ± 4.6 % compared to 55.37 ± 4.38 %) and heart (77.15 ± 9.52 % compared to 19.15 ± 7.93 %) (p <0.001). However, at high doses, 3D-CRT plans are much higher than VMAT: Dose to left lung V20Gy (36.22 ± 3.9 % compared to 22.62 ± 2.43 %), V30Gy (30.6 ± 5.97 % compared to 11.77 ± 2.53 %) and V40Gy (24.73 ± 8.59 % compared to 3.63 ± 2.02 %) (P <0.001). Similarly, the cardiac arrival dose of the 3D-CRT plan is higher than that of VMAT: V20Gy (11.54 ± 5.83 % compared to 9.49 ± 6.00 %, p> 0.05), V30Gy (9.25 ± 5.56 % compared to 2.13 ± 1.89 %) and V40 Gy (7.54 ± 5.03 % compared with 0.2 ± 0.25 %). Dose to coronary arteries also decreased significantly for VMAT plans compared to 3D-CRT: V20Gy (0.8 ± 1.01 % compared to 27.29 ± 15.19 %) V30Gy (0.00 % compared to 23.09 ± 10.73 %). Conclusion: VMAT is dosimetrically superior to the 3D-CRT for left‑sided breast cancer patients with regional nodes by dose coverage to PTV and good ability to avoid heart and lung and coronary arteries than. Key words: Breast cancer, Postmastectomy radiotherapy, Three-dimension conformal radiotherapy, Volumetric modulated arc therapy.

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