Hyperthermia Combined with Concurrent Radiochemotherapy for 373 Patients with Cervical Cancer Stage IB-IV

Author(s):  
Y. Wang ◽  
H. Chen
1995 ◽  
Vol 57 (3) ◽  
pp. 383-387 ◽  
Author(s):  
Ch. Kainz ◽  
P. Kohlberger ◽  
G. Sliutz ◽  
C. Tempfer ◽  
H. Heinzl ◽  
...  

Author(s):  
Doan Van Ngoc ◽  
Bui Van Lenh ◽  
Bui Dieu

This study investigates the value of magnetic resonance (MR) in assessing size, invasion, lymph node metastasis and cervical cancer stage classification in 117 patients who underwent surgery for whole hysterectomy and pelvic lymph node dredge in Vietnam National Cancer Hospital from July 2016 to August 2018. The study results show that tumor size accuracy (Acc) was 93.2%; vaginal invasion Sp was 98.2%; Acc, 96.6%, NPV, 98.2%; parametrial invasion Sp, 98.2%; Acc, 98.3%, NPV, 100%; pelvic wall invasion Acc , 98.3%; Sp was 115/116, 99.1%; NPV, 99.1%; metastatic lymph node Sp, 98.0%; Acc, 88.9%; NPV, 89.8%. The Acc of the value of MR in cervical cancer stage diagnosis from stage IB was 96.1%; and the overall Acc was 82.9%. The study results also show that the use of MRI in combination with clinical examination in size, invasion, metastasis and cervical cancer stage classification is necessary to improve the accuracy of the diagnosis.      Keywords  Cervical cancer, MRI of cervix. References [1] Globocan Cervical Cancer, Estimated Incidence, Mortality and Prevalence Worldwide in 2012. http://globocan.iarc.fr/old/FactSheets/ cancers/cervix - new.asp (accessed 30.06.2017). [2] Sala E, Wakely S, Senior E et al. MRI of malignant neoplasms of the uterine corpus and cervix. AJR Am J Roentgenol 188(6) (2007) 1577. [3] Hricak H, Lacey CG, Sandles LG et al. Invasive cervical carcinoma: comparison of MR imaging and surgical findings. Radiology 166(3) (1988) 623.[4] Ngo Thi Tinh, Research invasive level of cervical cancer on stage IB-IIA by clinical, magnetic resonance image and treatment results at K Hospital from 2007-2009. Doctor of Medicine thesis, Hanoi Medical University, 2011 (in Vietnamese).[5] Doan Van Ngoc. Research image characteristics and values of 1.5 tesla magnetic resonance in stage classification and follow treatment of cervical cancer. Doctor of Medicine thesis, Hanoi Medical University, 201 (in Vietnamese).[6] Susan JF, Ahmed MA, Masako YK et al. The Revised FIGO Staging System for Uterine Malignancies: Implications for MR Imaging. RadioGraphics 32(6) (2012). [7] Corrigendum to: Revised FIGO staging for carcinoma of the cervix uteri; Int J Gynecol Obstet 145 (2019) 129.[8] Hoang Duc Kiet. Magnetic resonance image of abdomen and pelvis. Medical Publishing House, (2016), pp.31-44, 329-334 (in Vietnamese).[9] Bourgioti C, Koutoulidis V, Chatoupis K et al. MRI findings before and after abdominal radical trachelectomy (ART) for cervical cancer: a prospective study and review of the literature. Clin Radiol. 69 (2014) 678.[10] Charis B, Konstantinos C, Lia AM, Current imaging strategies for the evaluation of uterine cervical cancer, World J Radiol, 28; 8(4) (2016) 342.    


1988 ◽  
Vol 29 (3) ◽  
pp. 321-332 ◽  
Author(s):  
Doo Sang Kim ◽  
Hyung Moon ◽  
Yeoun Yeoung Hwang ◽  
Sam Hyun Cho

2004 ◽  
Vol 13 (2) ◽  
pp. 113
Author(s):  
M. F. Aziz ◽  
Andrijono Andrijono ◽  
Laila Nuranna ◽  
Sigit Purbadi ◽  
Rukmini T. Mangunkusumo ◽  
...  

2019 ◽  
Vol 2 (3) ◽  
pp. 117-122
Author(s):  
Deri Edianto

The aim of this study is to evaluate response of cervical cancer stage IB – IIA after neoadjuvant chemotherapy based on VEGF expression. The data were collected from 51 patients’ cervical cancer stage IB – IIA parafin blocks who received chemotherapy ifosfamide – cisplatin before radical hysterectomy at General Hospital Adam Malik Medan. VEGF expression was evaluated from cervical biopsy tissue, and response therapy was evaluated based on tumor size clinically. 20 out of 51 samples with clinically complete response, and the rest are partial response. 18 out of 20 samples with clinically complete response have negative or weak VEGF expression, and 31 out of 51 samples patients were partialy response with moderate or strong VEGF expression. 23 cases with tumor size > 4 cm and 23 cases stage IIA expressed VEGF moderately or strong. Cervical cancer with tumor size < 4 cm and cervical cenncer stage IB with less expressed of VEGF have good response with chemotherapy adjuvant ifosfamide – cis platin.Keyword: ifosfamide-cisplatin, cervical cancer, VEGF


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