Pathologic complete remission after preoperative intracavitary radiotherapy of cervical cancer stage Ib and IIa is a strong prognostic factor for long-term survival: analysis of the Radiumhemmet data 1989-1991

2002 ◽  
Vol 12 (2) ◽  
pp. 158-170 ◽  
Author(s):  
C. Beskow ◽  
A.-K. Agren-Cronqvist ◽  
F. Granath ◽  
B. Frankendal ◽  
R. Lewensohn
Keyword(s):  
Cervical Cancer ◽  
Survival Analysis ◽  
Prognostic Factor ◽  
Complete Remission ◽  
Cancer Stage ◽  
Term Survival ◽  
Long Term Survival ◽  
Stage Ib ◽  
Pathologic Complete Remission

Predictive factors for achieving a pathologic complete remission (pCR) rate after neoadjuvant radiochemotherapy in locally advanced noninflammatory breast cancer: Results of a multivariant analysis.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e11556-e11556
Author(s):  
Edwin Boelke ◽  
Christiane Matuschek ◽  
Stephan L. Roth ◽  
Hans Bojar ◽  
Johann Wolfgang Janni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Complete Remission ◽  
Predictive Factors ◽  
Locally Advanced ◽  
Time Interval ◽  
Term Survival ◽  
Long Term Survival ◽  
Pathologic Complete Remission

e11556 Background: In contrast to neoadjuvant chemotherapy they are no predictive factors to estimate the pathologic complete remission (pCR) rate after preoperative chemotherapy (NRT-CHX) in locally advanced breast cancer (LABC). Methods: 315 LABC patients were included in this trial. They were treated during 1991-1998. The last follow up was in November 2011. Radiotherapy was applied with 50 Gy (5x2 Gy / week) to the breast and the supra-/infraclavicular lymph nodes. 101 patients received a 10 Gy interstitial boost (breast conservation). Chemotherapy (CMF, EC or Mitoxantron was applied in 192 patients prior to radiotherapy and in 113 patients simultaneously. Ten patients had no chemotherapy. Age, tumor grade, nodal status, hormone receptor status, simultaneous vs. sequential CHX and the time period up to surgery were examined in multivariate terms for pCR and overall survival. Results: The pCR rate for NRT-CHX after surgery was 29.2%. In multivariante analysis a longer time interval to surgery increased the probability of a pCR (HR 1,17 [95% CI 1,05-1,31], p<0,01). In term of overall survival, the achievement of a pCR is the strongest predictor for long term survival (HR 0,28 [95% CI 0,19-0,56], p<0,001). Conclusions: A long time interval to surgery (> 2 months) increases the probability of a pCR after NRT-CHX. Like in neoadjuvant CHX the achievement of a pCR is an important prognostic factor for long term survival.

Long-Term Survival Analysis of Pure Laparoscopic Versus Open Hepatectomy for Hepatocellular Carcinoma in Patients With Cirrhosis

2013 ◽  
Vol 257 (3) ◽  
pp. 506-511 ◽  
Author(s):  
Tan To Cheung ◽  
Ronnie T. P. Poon ◽  
Wai Key Yuen ◽  
Kenneth S. H. Chok ◽  
Caroline R. Jenkins ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Survival Analysis ◽  
Term Survival ◽  
Long Term Survival ◽  
Open Hepatectomy
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