Ceanothane and oleanane-type triterpenes from Talguenea quinquenervia have insecticidal activity against Cydia pomonella, Tenebrio molitor and Drosophila melanogaster

2015 ◽  
Vol 74 ◽  
pp. 759-766 ◽  
Author(s):  
Soledad Quiroz ◽  
Carlos L. Cespedes ◽  
Joel B. Alderete ◽  
Julio Alarcon
Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5094
Author(s):  
Soledad Quiroz-Carreño ◽  
Edgar Pastene-Navarrete ◽  
Cesar Espinoza-Pinochet ◽  
Evelyn Muñoz-Núñez ◽  
Luis Devotto-Moreno ◽  
...  

The Chilean plants Discaria chacaye, Talguenea quinquenervia (Rhamnaceae), Peumus boldus (Monimiaceae), and Cryptocarya alba (Lauraceae) were evaluated against Codling moth: Cydia pomonella L. (Lepidoptera: Tortricidae) and fruit fly Drosophila melanogaster (Diptera: Drosophilidae), which is one of the most widespread and destructive primary pests of Prunus (plums, cherries, peaches, nectarines, apricots, almonds), pear, walnuts, and chestnuts, among other. Four benzylisoquinoline alkaloids (coclaurine, laurolitsine, boldine, and pukateine) were isolated from the above mentioned plant species and evaluated regarding their insecticidal activity against the codling moth and fruit fly. The results showed that these alkaloids possess acute and chronic insecticidal effects. The most relevant effect was observed at 10 µg/mL against D. melanogaster and at 50 µg/mL against C. pomonella, being the alteration of the feeding, deformations, failure in the displacement of the larvae in the feeding medium of D. melanogaster, and mortality visible effects. In addition, the docking results show that these type of alkaloids present a good interaction with octopamine and ecdysone receptor showing a possible action mechanism.


2021 ◽  
Vol 24 (4) ◽  
pp. 786-791
Author(s):  
E.A. Estrella-Parra ◽  
E. Nolasco-Ontiveros ◽  
J. Alarcón-Enos ◽  
C.L. Céspedes-Acuña ◽  
A.M. García-Bores ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 766
Author(s):  
Gabriela Cristina Soares Rodrigues ◽  
Mayara dos Santos Maia ◽  
Andreza Barbosa Cavalcanti ◽  
Natália Ferreira de Sousa ◽  
Marcus Tullius Scotti ◽  
...  

Background: The growing demand for agricultural products has led to the misuse/overuse of insecticides; resulting in the use of higher concentrations and the need for ever more toxic products. Ecologically, bioinsecticides are considered better and safer than synthetic insecticides; they must be toxic to the target organism, yet with low or no toxicity to non-target organisms. Many plant extracts have seen their high insecticide potential confirmed under laboratory conditions, and in the search for plant compounds with bioinsecticidal activity, the Lamiaceae family has yielded satisfactory results. Objective: The aim of our study was to develop computer-assisted predictions for compounds with known insecticidal activity against Aphis gossypii and Drosophila melanogaster. Results and conclusion: Structure analysis revealed ent-kaurane, kaurene, and clerodane diterpenes as the most active, showing excellent results. We also found that the interactions formed by these compounds were more stable, or presented similar stability to the commercialized insecticides tested. Overall, we concluded that the compounds bistenuifolin L (1836) and bistenuifolin K (1931), were potentially active against A. gossypii enzymes; and salvisplendin C (1086) and salvixalapadiene (1195), are potentially active against D. melanogaster. We observed and highlight that the diterpenes bistenuifolin L (1836), bistenuifolin K (1931), salvisplendin C (1086), and salvixalapadiene (1195), present a high probability of activity and low toxicity against the species studied.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Angelica Plata-Rueda ◽  
Luis Carlos Martínez ◽  
Marcelo Henrique Dos Santos ◽  
Flávio Lemes Fernandes ◽  
Carlos Frederico Wilcken ◽  
...  

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