Insecticidal activity of sesquiterpenes skeleton synthesized by the conventional Robinson annulations reaction on Drosophila melanogaster

2013 ◽  
Vol 42 ◽  
pp. 268-272 ◽  
Author(s):  
Julio Alarcon ◽  
Claudio Lamilla ◽  
Carlos L. Cespedes
Keyword(s):  
Drosophila Melanogaster ◽  
Insecticidal Activity

scholarly journals Assessment of Insecticidal Activity of Benzylisoquinoline Alkaloids from Chilean Rhamnaceae Plants against Fruit-Fly Drosophila melanogaster and the Lepidopteran Crop Pest Cydia pomonella

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5094
Author(s):  
Soledad Quiroz-Carreño ◽  
Edgar Pastene-Navarrete ◽  
Cesar Espinoza-Pinochet ◽  
Evelyn Muñoz-Núñez ◽  
Luis Devotto-Moreno ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Insecticidal Activity ◽  
Cydia Pomonella ◽  
Fruit Fly ◽  
Codling Moth ◽  
Ecdysone Receptor ◽  
Action Mechanism ◽  
Benzylisoquinoline Alkaloids ◽  
Relevant Effect ◽  
Feeding Medium

The Chilean plants Discaria chacaye, Talguenea quinquenervia (Rhamnaceae), Peumus boldus (Monimiaceae), and Cryptocarya alba (Lauraceae) were evaluated against Codling moth: Cydia pomonella L. (Lepidoptera: Tortricidae) and fruit fly Drosophila melanogaster (Diptera: Drosophilidae), which is one of the most widespread and destructive primary pests of Prunus (plums, cherries, peaches, nectarines, apricots, almonds), pear, walnuts, and chestnuts, among other. Four benzylisoquinoline alkaloids (coclaurine, laurolitsine, boldine, and pukateine) were isolated from the above mentioned plant species and evaluated regarding their insecticidal activity against the codling moth and fruit fly. The results showed that these alkaloids possess acute and chronic insecticidal effects. The most relevant effect was observed at 10 µg/mL against D. melanogaster and at 50 µg/mL against C. pomonella, being the alteration of the feeding, deformations, failure in the displacement of the larvae in the feeding medium of D. melanogaster, and mortality visible effects. In addition, the docking results show that these type of alkaloids present a good interaction with octopamine and ecdysone receptor showing a possible action mechanism.

scholarly journals In Silico Studies of Lamiaceae Diterpenes with Bioinsecticide Potential against Aphis gossypii and Drosophila melanogaster

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 766
Author(s):  
Gabriela Cristina Soares Rodrigues ◽  
Mayara dos Santos Maia ◽  
Andreza Barbosa Cavalcanti ◽  
Natália Ferreira de Sousa ◽  
Marcus Tullius Scotti ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Insecticidal Activity ◽  
High Probability ◽  
Aphis Gossypii ◽  
Agricultural Products ◽  
Computer Assisted ◽  
In Silico Studies ◽  
Clerodane Diterpenes ◽  
Low Toxicity ◽  
Plant Compounds

Background: The growing demand for agricultural products has led to the misuse/overuse of insecticides; resulting in the use of higher concentrations and the need for ever more toxic products. Ecologically, bioinsecticides are considered better and safer than synthetic insecticides; they must be toxic to the target organism, yet with low or no toxicity to non-target organisms. Many plant extracts have seen their high insecticide potential confirmed under laboratory conditions, and in the search for plant compounds with bioinsecticidal activity, the Lamiaceae family has yielded satisfactory results. Objective: The aim of our study was to develop computer-assisted predictions for compounds with known insecticidal activity against Aphis gossypii and Drosophila melanogaster. Results and conclusion: Structure analysis revealed ent-kaurane, kaurene, and clerodane diterpenes as the most active, showing excellent results. We also found that the interactions formed by these compounds were more stable, or presented similar stability to the commercialized insecticides tested. Overall, we concluded that the compounds bistenuifolin L (1836) and bistenuifolin K (1931), were potentially active against A. gossypii enzymes; and salvisplendin C (1086) and salvixalapadiene (1195), are potentially active against D. melanogaster. We observed and highlight that the diterpenes bistenuifolin L (1836), bistenuifolin K (1931), salvisplendin C (1086), and salvixalapadiene (1195), present a high probability of activity and low toxicity against the species studied.

THE INSECTICIDAL ACTIVITY OF DDT AND RELATED COMPOUNDS AGAINST DIFFERENT INSECT SPECIES

1948 ◽  
Vol 26d (5) ◽  
pp. 301-306 ◽  
Author(s):  
H. C. Browning ◽  
S. K. Shapiro ◽  
M. Dubrûle
Keyword(s):  
Drosophila Melanogaster ◽  
Indicator Species ◽  
Insecticidal Activity ◽  
Tribolium Confusum ◽  
Oncopeltus Fasciatus ◽  
Insect Species ◽  
Blatella Germanica ◽  
Ephestia Kühniella ◽  
Related Compounds

DDT and its fluoro- and methyl-analogues, its carbinol and carbinol acetate, and monochlor-DDT (1-(4-chIorophenyl)-1-phenyl-2,2,2-trichloroethane) were tested for contact insecticidal activity against two beetles (Calandra granaria and Tribolium confusum), a moth (Ephestia kuhniella), a plant bug (Oncopeltus fasciatus), and a cockroach (Blatella germanica).Fluoro-DDT showed specificity against the cockroach and carbinol-DDT against the plant bug. Comparisons with the results of earlier testing against Drosophila melanogaster justified its use as an indicator species.

Insecticidal activity of essential oil from seeds of Poncirus trifoliata (L.) Raf.

2018 ◽  
Vol 47 (3) ◽  
pp. 413-419 ◽  
Author(s):  
Atiqur Rahman ◽  
Shah Alam Siddiqui ◽  
M Oliur Rahman ◽  
Sun Chul Kang
Keyword(s):  
Drosophila Melanogaster ◽  
Essential Oil ◽  
Medicinal Plant ◽  
Pest Control ◽  
Insecticidal Activity ◽  
Fruit Fly ◽  
Poncirus Trifoliata ◽  
Biologically Active ◽  
Anopheles Culicifacies ◽  
Potential Source

The essential oil from the seeds of oriental medicinal plant Poncirus trifoliata (L.) Raf. was tested for repellent and fumigant efficacy on fruit fly (Drosophila melanogaster) and mosquito (Anopheles culicifacies). The oil showed potent activity with 76.2 and 93.2% mortality in fumigant assay, and 77.1 and 93.2% repellent efficacy on fruit fly at doses of 100 and 200 μg/ml, respectively. The application of oil against mosquito showed 80.0% mortality in fumigant assay and 70.3% repellency at 100 μg/ml dose. Thus, essential oil of P. trifoliata seeds can be considered as a potential source of biologically active compounds for pest control.

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