scholarly journals Five-year point prevalence survey of healthcare-associated infections and antimicrobial use in a Japanese university hospital

2021 ◽  
pp. 100151
Author(s):  
Hiroshi Morioka ◽  
Mitsutaka Iguchi ◽  
Nobuyuki Tetsuka ◽  
Fumie Kinoshita ◽  
Yuka Tomita ◽  
...  
Keyword(s):  
Point Prevalence ◽  
University Hospital ◽  
Antimicrobial Use ◽  
Healthcare Associated Infections ◽  
Prevalence Survey ◽  
Japanese University ◽  
Point Prevalence Survey ◽  
Healthcare Associated

scholarly journals Antimicrobial use in acute care hospitals: national point prevalence survey on healthcare-associated infections and antimicrobial use, Switzerland, 2017

2019 ◽  
Vol 24 (33) ◽  
Author(s):  
Walter Zingg ◽  
Aliki Metsini ◽  
Céline Gardiol ◽  
Carlo Balmelli ◽  
Michael Behnke ◽  
...  
Keyword(s):  
Acute Care ◽  
Broad Spectrum ◽  
Acute Care Hospitals ◽  
Point Prevalence ◽  
Antimicrobial Use ◽  
Healthcare Associated Infections ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Broad Spectrum Antibiotics ◽  
Healthcare Associated

Background A point prevalence survey (PPS) on healthcare-associated infections (HAI) and antimicrobial use was conducted in Swiss acute care hospitals in 2017. Aim Our objective was to assess antimicrobial use in Swiss acute care hospitals. Methods All patients hospitalised in any acute care hospital in Switzerland were eligible. We used the most recent version of the PPS protocol of the European Centre for Disease Prevention and Control. Results Data from 12,931 patients of 96 hospitals were collected. Of these, 4,265 (33%; 95% confidence interval (CI): 32.2–33.8) were on 5,354 antimicrobials for 4,487 indications. Most of the 2,808 therapeutic indications addressed 1,886 community-acquired infections (67.2%; 95% CI: 65.4–68.9). Of the 1,176 surgical prophylaxes, 350 (29.8%; 95% CI: 27.1–32.4) exceeded the duration of 1 day. Of the 1,090 antimicrobial regimens that were changed, 309 (28.3%; 95% CI: 25.7–31.0) were escalated and 337 (30.9%; 95% CI: 28.2–33.7) were de-escalated. Amoxicillin/clavulanic acid was the most frequent antimicrobial (18.8%; 95% CI: 17.7–19.8), prescribed mainly for therapeutic indications (76.0%; 95% CI: 73.3–78.7). A total of 1,931 (37.4%; 95% CI: 36.1–38.8) of the 5,158 antimicrobials for systemic use were broad-spectrum antibiotics, most frequently third- and fourth-generation cephalosporins (35.9%; 95% CI: 33.8–38.1). Conclusions Antimicrobial consumption was at European average, the use of broad-spectrum antibiotics in the lower third. Swiss acute care hospitals should invest in antimicrobial stewardship, particularly in reducing the use of broad-spectrum antibiotics.

scholarly journals Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017

2018 ◽  
Vol 23 (46) ◽  
Author(s):  
Diamantis Plachouras ◽  
Tommi Kärki ◽  
Sonja Hansen ◽  
Susan Hopkins ◽  
Outi Lyytikäinen ◽  
...  
Keyword(s):  
Acute Care ◽  
Antimicrobial Agents ◽  
Acute Care Hospitals ◽  
Point Prevalence ◽  
Antimicrobial Use ◽  
Healthcare Associated Infections ◽  
Surgical Prophylaxis ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Healthcare Associated

Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016–17, we performed the second point-prevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2–31.9%). The most common indication for prescribing antimicrobials was treatment of a community-acquired infection, followed by treatment of HAI and surgical prophylaxis. Over half (54.2%) of antimicrobials for surgical prophylaxis were prescribed for more than 1 day. The most common infections treated by antimicrobials were respiratory tract infections and the most commonly prescribed antimicrobial agents were penicillins with beta-lactamase inhibitors. There was wide variation of patients on antimicrobials, in the selection of antimicrobial agents and in antimicrobial stewardship resources and activities across the participating countries. The results of the PPS provide detailed information on antimicrobial use in European acute care hospitals, enable comparisons between countries and hospitals, and highlight key areas for national and European action that will support efforts towards prudent use of antimicrobials.

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