scholarly journals A prospective cohort study to investigate functional outcome following avulsion fractures of the base of the fifth metatarsal

Injury Extra ◽  
2011 ◽  
Vol 42 (9) ◽  
pp. 133-134
Author(s):  
M. Shahid ◽  
S. Punwar ◽  
C. Bouland ◽  
G. Bannister
Keyword(s):  
Cohort Study ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Avulsion Fractures

An 18-month prospective cohort study of functional outcome of delirium in elderly patients: activities of daily living

2006 ◽  
Vol 18 (4) ◽  
pp. 681-700 ◽  
Author(s):  
Stephen Vida ◽  
Guillaume Galbaud du Fort ◽  
Ritsuko Kakuma ◽  
Louise Arsenault ◽  
Robert W. Platt ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cohort Study ◽  
Elderly Patients ◽  
Activities Of Daily Living ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Daily Living ◽  
Medical Problems

Objectives: To examine delirium, chronic medical problems and sociodemographic factors as predictors of activities of daily living (ADL), basic ADL (BADL) and instrumental ADL (IADL).Methods: A prospective cohort study of four groups of elderly patients examined in the emergency department (ED): those with delirium, dementia, neither, and both. All were aged 66 years or older and living at home. Delirium was assessed with the Confusion Assessment Method and dementia with the Informant Questionnaire on Cognitive Decline in the Elderly. Demographic variables and chronic medical problems were ascertained with questionnaires. Outcome was ADL at 6, 12 and 18 months, measured with the ADL subscale of the Older Americans Resources and Services instrument.Results: Univariate analyses suggested significantly poorer ADL, particularly IADL, at 18 months in the delirium versus the non-delirium group, in the absence of dementia only. Statistically significant independent predictors of poorer ADL at 18 months in the non-dementia groups were poorer initial ADL, stroke, Parkinson's disease, hypertension and female sex. Independent predictors of poorer BADL at 18 months in the non-dementia groups were poorer initial BADL, Parkinson's disease, stroke, cancer, colds/sinusitis/laryngitis, female sex and hypertension. Independent predictors of poorer IADL at 18 months in the non-dementia groups were poorer initial IADL, stroke, never-married status, colds/sinusitis/laryngitis, arthritis and hypertension, with Parkinson's disease showing a non-significant but numerically large regression coefficient.Conclusion: Rather than finding delirium to be a predictor of poorer functional outcome among survivors, we found an interaction between delirium and dementia and several plausible confounders, primarily chronic medical problems, although we cannot rule out the effect of misclassification or survivor bias.

Association of early inflammatory parameters after subarachnoid hemorrhage with functional outcome: A prospective cohort study

2015 ◽  
Vol 138 ◽  
pp. 177-183 ◽  
Author(s):  
Anke Höllig ◽  
Daniel Remmel ◽  
Birgit Stoffel-Wagner ◽  
Gerrit A. Schubert ◽  
Mark Coburn ◽  
...  
Keyword(s):  
Cohort Study ◽  
Subarachnoid Hemorrhage ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Inflammatory Parameters

scholarly journals Functional outcome after laparoscopic nerve-sparing sacrocolpopexy: a prospective cohort study

2018 ◽  
Vol 97 (6) ◽  
pp. 744-750 ◽  
Author(s):  
Corina Christmann-Schmid ◽  
Isabell Koerting ◽  
Esther Ruess ◽  
Ivo Faehnle ◽  
Jörg Krebs
Keyword(s):  
Cohort Study ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Nerve Sparing

scholarly journals Functional and Radiological Outcome of Type ΙΙΙ Supracondylar Fracture of Humerus Treated by Crossed Versus Lateral Pinning a Prospective Cohort Study Conducted in a Tertiary Health Care Centre in Thiruvananthapuram, Kerala

2021 ◽  
Vol 8 (26) ◽  
pp. 2300-2305
Author(s):  
Anand Narayanan ◽  
Subramanian Vaidyanathan
Keyword(s):  
Cohort Study ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Closed Reduction ◽  
Prospective Cohort ◽  
Supracondylar Fracture ◽  
Percutaneous Pinning ◽  
Pin Fixation ◽  
Significant Difference ◽  
Carrying Angle

BACKGROUND Supracondylar fracture of humerus is a common fracture in children. Closed manipulative reduction and percutaneous K-wire fixation is the most widely recognized treatment method for displaced supracondylar humerus fracture in children but controversy persists regarding the ideal pin fixation technique. The purpose of this study was to compare the radiological and functional outcome of lateral entry pinning with that of crossed pinning fixation for Gartland type III supracondylar humerus fractures in children. METHODS This prospective cohort study was conducted in Govt. Medical College Hospital, Thiruvananthapuram from February, 2015 to September, 2016. A total of 54 patients who satisfied the inclusion and exclusion criteria were enrolled in the study. They were allocated to Group A (crossed pin fixation) and Group B (lateral pin) fixation with 27 patients in each. All the cases of percutaneous pinning were done according to a uniform standardized technique. The patients were reevaluated at post-operative day, three weeks, and three months after the surgery. Following information were recorded as outcome measures: (i) carrying angle (ii) range of motion (iii) modified Flynn’s criteria. (v) Baumann’s angle (vi) neurovascular injury. RESULTS There was no statistically significant difference between crossed and lateral pinning with regard to mean Baumann's angle, carrying angle, complication rate, stability and functional outcome, but there was evidence of iatrogenic ulnar nerve injury (3.7 %) in crossed pinning group. There was one case of pin tract infection. CONCLUSIONS There is no statistically significant difference between the radiological and functional outcome provided by crossed pin fixation method and lateral pin fixation methods. Closed reduction and percutaneous pin fixation are safe and efficient methods for fixation of displaced supracondylar fractures of the humerus. Closed reduction and percutaneous pin fixation for displaced supracondylar factures of the humerus in children gives good functional and cosmetic results. KEYWORDS Humerus, Percutaneous Pinning, Supracondylar Fracture

EXPRESS: Inflammatory cytokines, high sensitivity CRP, and risk of 1-year vascular events, death and poor functional outcome after stroke and TIA

2021 ◽  
pp. 174749302199559
Author(s):  
Sarah A Coveney ◽  
Sean Murphy ◽  
Orina Belton ◽  
Tim Cassidy ◽  
Morgan Crowe ◽  
...  
Keyword(s):  
Cohort Study ◽  
Functional Outcome ◽  
Inflammatory Cytokines ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Cox Regression ◽  
High Sensitivity ◽  
Stroke Recurrence ◽  
Vascular Events ◽  
Poor Functional Outcome

Background Inflammation driven by pro-inflammatory cytokines is a new therapeutic target in coronary disease. Few data exist on the association of key upstream cytokines and post-stroke recurrence. In a prospective cohort study, we investigated the association between pivotal cytokines, CRP and 1-year outcomes. Methods BIO-STROKETIA is a multi-centre prospective cohort study of non-severe ischemic stroke (mRS≤3) and TIA. Controls were patients with transient symptoms attending TIA clinics with non-ischemic final diagnosis. Exclusion criteria were severe stroke, infection and other pro-inflammatory disease. High-sensitivity serum C-reactive protein (CRP) and cytokines (interleukin [IL] 6, IL-1β, IL-8, IL-10, IL-12, interferon-γ [IFN-γ], tumor-necrosis factor-α [TNF-α]) were measured. The primary outcome was 1-year recurrent stroke/coronary events (fatal and non-fatal). Results 680 patients (439 stroke, 241 TIA) and 68 controls were included. IL-6, IL-1β, IL-8, IFN-γ, TNF-α, and CRP were higher in stroke/TIA cases (p≤0.01 for all). On multivariable Cox regression, IL-6, IL-8, and CRP independently predicted 1-year recurrent vascular events (adjusted HRs [aHR] per-quartile increase IL-6 1.31,CI 1.02-1.68, p=0.03; IL-8 1.47, CI 1.15-1.89, p=0.002; CRP 1.28 CI, 1.01-1.62, p=0.04). IL-6 (aHR 1.98, CI 1.26-3.14, p=0.003) and CRP (aHR 1.81, CI 1.20-2.74, p=0.005) independently predicted 1-year fatality. IL-6 and CRP (adjusted OR per-unit increase 1.02, CI 1.01-1.04) predicted poor functional outcome, with a trend for IL-1 (p=0.054). Conclusion Baseline inflammatory cytokines independently predicted late recurrence, supporting a rationale for randomised trials of anti-inflammatory agents for prevention after stroke and suggesting that targeted therapy to high-risk patients with high baseline inflammation may be beneficial.

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