Two machine-learning techniques for mining solutions of the ReleasePlanner™ decision support system

2014 ◽  
Vol 259 ◽  
pp. 474-489 ◽  
Author(s):  
Gengshen Du ◽  
Guenther Ruhe
2019 ◽  
Vol 892 ◽  
pp. 274-283
Author(s):  
Mohammed Ashikur Rahman ◽  
Afidalina Tumian

Now a day, clinical decision support systems (CDSS) are widely used in the cardiac care due to the complexity of the cardiac disease. The objective of this systematic literature review (SLR) is to identify the most common variables and machine learning techniques used to build machine learning-based clinical decision support system for cardiac care. This SLR adopts the Preferred Reporting Item for Systematic Review and Meta-Analysis (PRISMA) format. Out of 530 papers, only 21 papers met the inclusion criteria. Amongst the 22 most common variables are age, gender, heart rate, respiration rate, systolic blood pressure and medical information variables. In addition, our results have shown that Simplified Acute Physiology Score (SAPS), Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) are some of the most common assessment scales used in CDSS for cardiac care. Logistic regression and support vector machine are the most common machine learning techniques applied in CDSS to predict mortality and other cardiac diseases like sepsis, cardiac arrest, heart failure and septic shock. These variables and assessment tools can be used to build a machine learning-based CDSS.


2020 ◽  
Vol 16 (4) ◽  
pp. 407-419
Author(s):  
Aytun Onay ◽  
Melih Onay

Background: Virtual screening of candidate drug molecules using machine learning techniques plays a key role in pharmaceutical industry to design and discovery of new drugs. Computational classification methods can determine drug types according to the disease groups and distinguish approved drugs from withdrawn ones. Introduction: Classification models developed in this study can be used as a simple filter in drug modelling to eliminate potentially inappropriate molecules in the early stages. In this work, we developed a Drug Decision Support System (DDSS) to classify each drug candidate molecule as potentially drug or non-drug and to predict its disease group. Methods: Molecular descriptors were identified for the determination of a number of rules in drug molecules. They were derived using ADRIANA.Code program and Lipinski's rule of five. We used Artificial Neural Network (ANN) to classify drug molecules correctly according to the types of diseases. Closed frequent molecular structures in the form of subgraph fragments were also obtained with Gaston algorithm included in ParMol Package to find common molecular fragments for withdrawn drugs. Results: We observed that TPSA, XlogP Natoms, HDon_O and TPSA are the most distinctive features in the pool of the molecular descriptors and evaluated the performances of classifiers on all datasets and found that classification accuracies are very high on all the datasets. Neural network models achieved 84.6% and 83.3% accuracies on test sets including cardiac therapy, anti-epileptics and anti-parkinson drugs with approved and withdrawn drugs for drug classification problems. Conclusion: The experimental evaluation shows that the system is promising at determination of potential drug molecules to classify drug molecules correctly according to the types of diseases.


10.28945/4024 ◽  
2018 ◽  
Vol 15 ◽  
pp. 043-056
Author(s):  
Joseph K Mbugua ◽  
WATANYOO Suksa-ngiam

Aim/Purpose: Although cassava is one of the crops that can be grown during the dry season in Northeastern Thailand, most farmers in the region do not know whether the crop can grow in their specific areas because the available agriculture planning guideline provides only a generic list of dry-season crops that can be grown in the whole region. The purpose of this research is to develop a predictive model that can be used to predict suitable areas for growing cassava in Northeastern Thailand during the dry season. Background: This paper develops a decision support system that can be used by farmers to assist them determine if cassava can be successfully grown in their specific areas. Methodology: This study uses satellite imagery and data on land characteristics to develop a machine learning model for predicting suitable areas for growing cassava in Thailand’s Nakhon-Phanom province. Contribution: This research contributes to the body of knowledge by developing a novel model for predicting suitable areas for growing cassava. Findings: This study identified elevation and Ferric Acrisols (Af) soil as the two most important features for predicting the best-suited areas for growing cassava in Nakhon-Phanom province, Thailand. The two-class boosted decision tree algorithm performs best when compared with other algorithms. The model achieved an accuracy of .886, and .746 F1-score. Recommendations for Practitioners: Farmers and agricultural extension agents will use the decision support system developed in this study to identify specific areas that are suitable for growing cassava in Nakhon-Phanom province, Thailand Recommendation for Researchers: To improve the predictive accuracy of the model developed in this study, more land and crop characteristics data should be incorporated during model development. The ground truth data for areas growing cassava should also be collected for a longer period to provide a more accurate sample of the areas that are suitable for cassava growing. Impact on Society: The use of machine learning for the development of new farming systems will enable farmers to produce more food throughout the year to feed the world’s growing population. Future Research: Further studies should be carried out to map other suitable areas for growing dry-season crops and to develop decision support systems for those crops.


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