Variables Influencing Machine Learning-Based Cardiac Decision Support System: A Systematic Literature Review

2019 ◽  
Vol 892 ◽  
pp. 274-283
Author(s):  
Mohammed Ashikur Rahman ◽  
Afidalina Tumian

Now a day, clinical decision support systems (CDSS) are widely used in the cardiac care due to the complexity of the cardiac disease. The objective of this systematic literature review (SLR) is to identify the most common variables and machine learning techniques used to build machine learning-based clinical decision support system for cardiac care. This SLR adopts the Preferred Reporting Item for Systematic Review and Meta-Analysis (PRISMA) format. Out of 530 papers, only 21 papers met the inclusion criteria. Amongst the 22 most common variables are age, gender, heart rate, respiration rate, systolic blood pressure and medical information variables. In addition, our results have shown that Simplified Acute Physiology Score (SAPS), Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) are some of the most common assessment scales used in CDSS for cardiac care. Logistic regression and support vector machine are the most common machine learning techniques applied in CDSS to predict mortality and other cardiac diseases like sepsis, cardiac arrest, heart failure and septic shock. These variables and assessment tools can be used to build a machine learning-based CDSS.

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Gwang Hyeon Choi ◽  
Jihye Yun ◽  
Jonggi Choi ◽  
Danbi Lee ◽  
Ju Hyun Shim ◽  
...  

Abstract There is a significant discrepancy between the actual choice for initial treatment option for hepatocellular carcinoma (HCC) and recommendations from the currently used BCLC staging system. We develop a machine learning-based clinical decision support system (CDSS) for recommending initial treatment option in HCC and predicting overall survival (OS). From hospital records of 1,021 consecutive patients with HCC treated at a single centre in Korea between January 2010 and October 2010, we collected information on 61 pretreatment variables, initial treatment, and survival status. Twenty pretreatment key variables were finally selected. We developed the CDSS from the derivation set (N = 813) using random forest method and validated it in the validation set (N = 208). Among the 1,021 patients (mean age: 56.9 years), 81.8% were male and 77.0% had positive hepatitis B BCLC stages 0, A, B, C, and D were observed in 13.4%, 26.0%, 18.0%, 36.6%, and 6.3% of patients, respectively. The six multi-step classifier model was developed for treatment decision in a hierarchical manner, and showed good performance with 81.0% of accuracy for radiofrequency ablation (RFA) or resection versus not, 88.4% for RFA versus resection, and 76.8% for TACE or not. We also developed seven survival prediction models for each treatment option. Our newly developed HCC-CDSS model showed good performance in terms of treatment recommendation and OS prediction and may be used as a guidance in deciding the initial treatment option for HCC.


IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 185676-185687
Author(s):  
Noha Ossama El-Ganainy ◽  
Ilangko Balasingham ◽  
Per Steinar Halvorsen ◽  
Leiv Arne Rosseland

Sign in / Sign up

Export Citation Format

Share Document