scholarly journals Recent Advances in Recording and Modulation Technologies for Next-generation Neural Interfaces

iScience ◽  
2021 ◽  
pp. 103550
Author(s):  
Ji-won Hong ◽  
Chanwoong Yoon ◽  
Kyunghyun Jo ◽  
Joon Hee Won ◽  
Seongjun Park
Keyword(s):  
Neural Interfaces ◽  
Next Generation ◽  
Recent Advances

scholarly journals Next-generation androgen receptor inhibitors in non-metastatic castration-resistant prostate cancer

2020 ◽  
Vol 12 ◽  
pp. 175883592097813
Author(s):  
Pernelle Lavaud ◽  
Clément Dumont ◽  
Constance Thibault ◽  
Laurence Albiges ◽  
Giulia Baciarello ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Overall Survival ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Next Generation ◽  
Castration Resistant Prostate Cancer ◽  
Free Survival ◽  
Castration Resistant ◽  
Recent Advances

Until recently, continuing androgen deprivation therapy (ADT) and closely monitoring patients until evolution towards metastatic castration-resistant prostate cancer (CRPC) were recommended in men with non-metastatic CRPC (nmCRPC). Because delaying the development of metastases and symptoms in these patients is a major issue, several trials have investigated next-generation androgen receptor (AR) axis inhibitors such as apalutamide, darolutamide, and enzalutamide in this setting. This review summarizes the recent advances in the management of nmCRPC, highlighting the favourable impact of next-generation AR inhibitors on metastases-free survival, overall survival and other clinically meaningful endpoints.

scholarly journals The integration of emerging omics approaches to advance precision medicine: How can regulatory science help?

2018 ◽  
Vol 2 (5) ◽  
pp. 295-300
Author(s):  
Joan E. Adamo ◽  
Robert V. Bienvenu ◽  
F. Owen Fields ◽  
Soma Ghosh ◽  
Christina M. Jones ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Precision Medicine ◽  
Working Group ◽  
Regulatory Science ◽  
Translational Science ◽  
Next Generation ◽  
Clinical Validity ◽  
Knowledge Gaps ◽  
Recent Advances ◽  
Generation Sequencing

Building on the recent advances in next-generation sequencing, the integration of genomics, proteomics, metabolomics, and other approaches hold tremendous promise for precision medicine. The approval and adoption of these rapidly advancing technologies and methods presents several regulatory science considerations that need to be addressed. To better understand and address these regulatory science issues, a Clinical and Translational Science Award Working Group convened the Regulatory Science to Advance Precision Medicine Forum. The Forum identified an initial set of regulatory science gaps. The final set of key findings and recommendations provided here address issues related to the lack of standardization of complex tests, preclinical issues, establishing clinical validity and utility, pharmacogenomics considerations, and knowledge gaps.

scholarly journals Organic electrode coatings for next-generation neural interfaces

2014 ◽  
Vol 7 ◽  
Author(s):  
Ulises A. Aregueta-Robles ◽  
Andrew J. Woolley ◽  
Laura A. Poole-Warren ◽  
Nigel H. Lovell ◽  
Rylie A. Green
Keyword(s):  
Neural Interfaces ◽  
Next Generation ◽  
Organic Electrode

Perspectives and challenges in multilayer ceramic capacitors for next generation electronics

2019 ◽  
Vol 7 (32) ◽  
pp. 9782-9802 ◽  
Author(s):  
Kootak Hong ◽  
Tae Hyung Lee ◽  
Jun Min Suh ◽  
Seok-Hyun Yoon ◽  
Ho Won Jang
Keyword(s):  
Dielectric Materials ◽  
Next Generation ◽  
Multilayer Ceramic Capacitors ◽  
High Capacitance ◽  
Recent Advances ◽  
Ceramic Capacitors ◽  
Critical Issues ◽  
Multilayer Ceramic

This review highlights the critical issues and recent advances in developing highly volumetric-efficient and high capacitance MLCCs from the viewpoint of designing dielectric materials.

Towards next-generation label-free biosensors: recent advances in whispering gallery mode sensors

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1190-1205 ◽  
Author(s):  
Eugene Kim ◽  
Martin D. Baaske ◽  
Frank Vollmer
Keyword(s):  
Real World ◽  
Whispering Gallery Mode ◽  
Label Free ◽  
Next Generation ◽  
Whispering Gallery ◽  
Recent Advances ◽  
Real World Applications

We review recent advances achieved in the field of optical whispering gallery mode biosensors. We discuss major challenges that these label-free sensors are faced with on their way towards future real-world applications and introduce different approaches suggested to overcome these issues. We furthermore highlight their potential future applications.

Recent advances of Li4Ti5O12 as a promising next generation anode material for high power lithium-ion batteries

2015 ◽  
Vol 3 (11) ◽  
pp. 5750-5777 ◽  
Author(s):  
Ting-Feng Yi ◽  
Shuang-Yuan Yang ◽  
Ying Xie
Keyword(s):  
Lithium Ion Batteries ◽  
Anode Material ◽  
High Power ◽  
Lithium Ion ◽  
Next Generation ◽  
The Past ◽  
Recent Advances

This review highlights breakthroughs in the past decade in the synthesis and the modification of both the chemistry and morphology of Li4Ti5O12.

Recent advances in non-chemically amplified photoresists for next generation IC technology

RSC Advances ◽  
2016 ◽  
Vol 6 (78) ◽  
pp. 74462-74481 ◽  
Author(s):  
Subrata Ghosh ◽  
Chullikkattil P. Pradeep ◽  
Satinder K. Sharma ◽  
Pulikanti Guruprasad Reddy ◽  
Satyendra P. Pal ◽  
...  
Keyword(s):  
Present Article ◽  
Next Generation ◽  
Chemically Amplified ◽  
Recent Advances ◽  
Ic Technology

The present article reviews the recent advances in the area of non-chemically amplified photoresists particularly for sub-30 nm nodes.

scholarly journals Next-generation sequencing for endocrine cancers: Recent advances and challenges

Tumor Biology ◽  
2017 ◽  
Vol 39 (5) ◽  
pp. 101042831769837 ◽  
Author(s):  
Padmanaban S Suresh ◽  
Thejaswini Venkatesh ◽  
Rie Tsutsumi ◽  
Abhishek Shetty
Keyword(s):  
Next Generation Sequencing ◽  
Drug Targets ◽  
Current View ◽  
Endocrine Tumors ◽  
Next Generation ◽  
Clinical Genetic ◽  
Clinical Genetic Testing ◽  
Recent Advances ◽  
Microarray Analyses ◽  
Generation Sequencing

Contemporary molecular biology research tools have enriched numerous areas of biomedical research that address challenging diseases, including endocrine cancers (pituitary, thyroid, parathyroid, adrenal, testicular, ovarian, and neuroendocrine cancers). These tools have placed several intriguing clues before the scientific community. Endocrine cancers pose a major challenge in health care and research despite considerable attempts by researchers to understand their etiology. Microarray analyses have provided gene signatures from many cells, tissues, and organs that can differentiate healthy states from diseased ones, and even show patterns that correlate with stages of a disease. Microarray data can also elucidate the responses of endocrine tumors to therapeutic treatments. The rapid progress in next-generation sequencing methods has overcome many of the initial challenges of these technologies, and their advantages over microarray techniques have enabled them to emerge as valuable aids for clinical research applications (prognosis, identification of drug targets, etc.). A comprehensive review describing the recent advances in next-generation sequencing methods and their application in the evaluation of endocrine and endocrine-related cancers is lacking. The main purpose of this review is to illustrate the concepts that collectively constitute our current view of the possibilities offered by next-generation sequencing technological platforms, challenges to relevant applications, and perspectives on the future of clinical genetic testing of patients with endocrine tumors. We focus on recent discoveries in the use of next-generation sequencing methods for clinical diagnosis of endocrine tumors in patients and conclude with a discussion on persisting challenges and future objectives.

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