scholarly journals Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevation

2005 ◽  
Vol 45 (6) ◽  
pp. 838-845 ◽  
Author(s):  
William S. Weintraub ◽  
Elizabeth M. Mahoney ◽  
Andre Lamy ◽  
Steven Culler ◽  
Yong Yuan ◽  
...  
2014 ◽  
Vol 174 (1) ◽  
pp. 127-128 ◽  
Author(s):  
Nuccia Morici ◽  
Stefano De Servi ◽  
Anna Toso ◽  
Ernesto Murena ◽  
Paola Tamburrini ◽  
...  

2009 ◽  
Vol 32 (3) ◽  
pp. 142-147 ◽  
Author(s):  
Stefanos G. Foussas ◽  
Michael N. Zairis ◽  
Vasilios G. Tsirimpis ◽  
Stamatis S. Makrygiannis ◽  
Nikolaos G. Patsourakos ◽  
...  

Author(s):  
Sigrun Halvorsen ◽  
Giuseppe Gargiulo ◽  
Marco Valgimigli ◽  
Kurt Huber

Antithrombotic therapy is a major cornerstone in the treatment of acute coronary syndromes (ACS), as thrombus formation upon a plaque rupture or an erosion plays a pivotal role in non-ST-segment elevation as well as ST-segment elevation acute coronary syndromes. Both acute and long-term oral antiplatelet therapies, targeting specific platelet activation pathways, have demonstrated significant short- and long-term benefits. The use of anticoagulants is currently largely confined to the acute setting, except in patients with a clear indication for long-term treatment, including atrial fibrillation or the presence of intraventricular thrombi. Despite the benefit of primary percutaneous coronary intervention in ST-segment elevation myocardial infarction, fibrinolytic therapy continues to play an important role throughout the world. In this chapter, the fibrinolytic, antiplatelet, and anticoagulant agents used in the management of acute coronary syndrome patients are discussed.


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