scholarly journals GW27-e0977 The research of L type calcium channel in Turn SERCA 2a genetic model for acute atrial fibrillation atrial muscle cell

2016 ◽  
Vol 68 (16) ◽  
pp. C35
Author(s):  
Luo Jian ◽  
Wang Ling-Peng
2020 ◽  
Author(s):  
Hua Wen ◽  
Kazumi Eckenstein ◽  
Vivien Weihrauch ◽  
Christian Stigloher ◽  
Paul Brehm

AbstractThe escape response and rhythmic swimming in zebrafish are distinct behaviors mediated by two functionally distinct motoneuron (Mn) types. The primary (1°Mn) type depresses, has a large quantal content (Qc), and a high release probability (Pr). Conversely, the secondary (2°Mn) type facilitates and has low and variable Qc and Pr. This functional duality matches well the distinct associated behaviors, with the 1°Mn providing the strong, singular C-bend initiating escape and the 2°Mn confers weaker, rhythmic contractions. Contributing to these functional distinctions is our identification of P/Q type calcium channels mediating transmitter release in 1°Mns and N type channels in 2°Mns. Remarkably, despite these functional and behavioral distinctions, all ~15 individual synapses on each muscle cell are shared by a 1°Mn bouton and at least one 2°Mn bouton. This novel blueprint of synaptic sharing provides an efficient way of controlling two different behaviors at the level of a single postsynaptic cell.


1984 ◽  
Vol 170 (2) ◽  
pp. 163-179 ◽  
Author(s):  
A. Rambourg ◽  
D. Segretain ◽  
Y. Clermont

1996 ◽  
Vol 131 (4) ◽  
pp. 778-789 ◽  
Author(s):  
Kumitake Hashiba ◽  
Osmar Antonio Centurion ◽  
Akihiko Shimizu

2015 ◽  
Vol 48 (5) ◽  
pp. 861-866 ◽  
Author(s):  
Frida Sandberg ◽  
Valentina D.A. Corino ◽  
Luca T. Mainardi ◽  
Sara R. Ulimoen ◽  
Steve Enger ◽  
...  

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