Chronic Hand Dermatitis: Impact Of Patch Testing and Allergen Avoidance Post Treatment

The electronics industry is becoming an important mainstream in the workforce in some developed countries and in Taiwan. Among patients with occupational hand dermatitis in northern Taiwan, workers from electronics industries were one of the most important groups. We conducted a field investigation to determine the prevalence, patterns and risk factors of occupational hand dermatoses among electronics workers. The survey was conducted in five electronics plants using a self-administered questionnaire on skin symptoms and risk factors. Skin examination and patch testing were followed for those with symptoms compatible with hand dermatitis. A total of 3070 workers completed the questionnaire. Among them, 302 (9.8%) reported to have symptoms (itching and with either redness/scaling) compatible with contact dermatitis on hands. Hand dermatitis was associated with working in the fabrication unit and personal history of atopy and metal allergy, as well as the following job titles: wafer bonding, cutting, printing/photomasking, softening/degluing, impregnation and tin plating. Among those with reported hand dermatitis, 183 completed skin examination and patch testing, 65/183 (35.5%) were diagnosed as having irritant contact dermatitis (ICD) and 7/183 (3.8%) allergic contact dermatitis. The most important allergens were nickel, cobalt and phenylenediamine. In conclusion, Taiwanese electronics workers have a high risk of having hand dermatitis, especially ICD. Preventive efforts should be focused on the workers with risk factors or at certain worksites.

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Hand Dermatitis in Adults Referred for Patch Testing: Analysis of North American Contact Dermatitis Group Data, 2000–2016

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2020.11.054 ◽

2020 ◽

Author(s):

Jonathan I. Silverberg ◽

Erin M. Warshaw ◽

Amber R. Atwater ◽

Howard I. Maibach ◽

Kathryn A. Zug ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Testing ◽

North American ◽

Hand Dermatitis ◽

Group Data

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Patch Testing in Occupational Hand Dermatitis

Dermatologic Clinics ◽

10.1016/s0733-8635(18)30687-9 ◽

1988 ◽

Vol 6 (1) ◽

pp. 43-46 ◽

Cited By ~ 9

Author(s):

Robert L. Rietschel

Keyword(s):

Patch Testing ◽

Hand Dermatitis

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A study of profile of contact dermatitis in housewives with reference to vegetables, soaps and detergents

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20183155 ◽

2018 ◽

Vol 4 (3) ◽

pp. 332

Author(s):

Vidushi Malhotra ◽

Alka Dogra ◽

Sunil Kumar Gupta ◽

Sandeep Kaur

Keyword(s):

Contact Dermatitis ◽

Patch Testing ◽

Hand Eczema ◽

Age Group ◽

Nickel Sulphate ◽

Hand Dermatitis ◽

Wear And Tear ◽

Morphological Diagnosis ◽

Almost All ◽

Allergic Contact

Background: Contact dermatitis in housewives is a common dermatological problem as almost all housewives have to handle vegetables, fruits, soaps and detergents. The purpose of this project was to study etiologic profile of contact dermatitis occurring in housewives.Methods: One hundred housewives, clinically diagnosed as having contact dermatitis, were randomly selected for the study. Each patient was then subjected to patch testing using the Indian standard battery and certain indigenously prepared antigens i.e. vegetables, soaps and detergents. The first reading was taken 60 minutes with second reading at 96 hours. Reading equal to or more than 1+ was considered to be a positive test.Results: Majority patients were in the age group of 20-30 years. Morphological diagnosis was wear and tear dermatitis in 43%, discoid eczema (19%), fingertip eczema (16%), hyperkeratotic (15%) and pompholyx (7%). Nickel sulphate was found to be the commonest allergen (19%) followed by para-phenylenediamine (8%), fragnance mix (7%), Balsam of Peru (6%), parthenium (6%) and cobalt (5%). Amongst vegetables, the commonest culprit was garlic. Allergic reaction to detergents was positive in 13% patients. Forty-four percent of the cases tested positive to the suspected allergen whereas 31% patients tested positive for allergens not initially suspected of causing contact dermatitis in them.Conclusions: Thus patch testing is an important tool in establishing the cause of allergic contact dermatitis of the hands in housewives in whom the hand eczema is multifactorial. This enables the correct etiological diagnosis and proper management of housewives with hand dermatitis.

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Characteristics of Patients With Hand Dermatitis Referred to the Contact Dermatitis Unit of a Tertiary Hospital and Impact of Patch Testing on Diagnosis

Actas Dermo-Sifiliográficas (English Edition) ◽

10.1016/s1578-2190(09)70106-4 ◽

2009 ◽

Vol 100 (6) ◽

pp. 493-498

Author(s):

J.M. Carrascosa ◽

F. Benvenuti ◽

C. Rodríguez ◽

C. Ferrándiz

Keyword(s):

Contact Dermatitis ◽

Patch Testing ◽

Tertiary Hospital ◽

Hand Dermatitis

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Patch testing and contact allergen avoidance in patients with lichen planopilaris and/or frontal fibrosing alopecia: A cohort study

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2020.01.026 ◽

2020 ◽

Vol 83 (2) ◽

pp. 659-661

Author(s):

Sonya Prasad ◽

Dustin H. Marks ◽

Laura J. Burns ◽

Brianna De Souza ◽

Elizabeth A. Flynn ◽

...

Keyword(s):

Cohort Study ◽

Patch Testing ◽

Allergen Avoidance ◽

Lichen Planopilaris ◽

Contact Allergen

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Ultrastructure of bronchopulmonary lavage cells from bovines administered 3-methylindole: II. 24 hours post-treatment

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100111124 ◽

1984 ◽

Vol 42 ◽

pp. 202-203

Author(s):

Amreek Singh ◽

Judith M. McLaren ◽

Onkar S. Atwal ◽

Peter Eyre

Keyword(s):

Plasma Cells ◽

Ciliated Cell ◽

Lavage Fluid ◽

Treated Group ◽

Post Treatment ◽

Lung Edema ◽

Ciliated Cells ◽

Thin Sections ◽

Variable Diameter ◽

Cell Pellet

Introduction3-methylindole (MI), a rumen metabolite of the amino acid L-tryptophan, has been shown to produce bovine pulmonary edema and emphysema. The airways contain free and exfoliated cells. A morphologic analysis of these cells may complement the understanding of the mechanism of lung edema. Ultrastructure of the bronchopulmonary lavage (BL) cells 24 h following MI oral administration to calves is described in this experiment. The 12 hours post-treatment results were described earlier.Materials and MethodsTwo Holstein-Friesian calves were each administered an oral dose of 0.2 g MI/Kg body weight and another two calves served as controls. The animals were euthanized with sodium pentabarbitol 24 h after receiving the compound. The lungs and trachea were removed and 0.1 M sodium phosphate buffered saline was infused into the lungs through the trachea. Glutaraldehyde fixative was added to the recovered BL fluid so as to form a 1% solution. The fluid was centrifuged and the resulting cell pellet was suspended in the buffer. The procedures were repeated on the suspension; the pellet was post-fixed in osmium tetroxide and was processed by conventional methods of section preparations for TEM examination. Lung samples from caudal lobes were fixed in 1.5% glutaraldehyde to obtain tissue sections for TEM.Results and DiscussionPulmonary alveolar macrophages (AM), neutrophils, ciliated epithelial cells, globule leukocytes and plasma cells were recovered from the BL fluid of the control and Mi-administered calves. Ciliated cells and globule leukocytes could not be harvested from the controls. The AM obtained from the treated calves (Fig. 1) in comparison with similar cells from the controls were larger, and contained large membrane-limited inclusions (phagolysosomes). There was a remarkable similarity between the lavaged AM and the AM studied in thin sections of lung (cf. Fig. 1 and Fig. 2). The neutrophil was the second most abundant cell type retrieved from the lavage fluid from the calves of control or treated group. Except for scanty pseudopodia in the neutrophils obtained from the Mi-receiving calves, the cells appeared unaltered (Fig. 3). Ciliated cells were abundant in the BL fluid of Mi-ingesting calves. A heterogeneous collection of vesicles filled the ciliated cell cytoplasm (Fig. 3). Globule leukocytes were commonly observed among BL cells of treated calves. The globule leukocytes were ca. 15 μm in diameter and contained round or elliptical nuclei with conspicuous nucleoli. The cytoplasmic granules, which are a prominent feature of globule leukocytes, were electron-opaque and had a variable diameter (0.5-3.0 μm). A one-line account of globule leukocytes in the bronchi of steers administered MI has appeared. Plasma cells were rare. Ultrastructure of BL cells is compatible with their response to chemical insult by MI.

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