Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia

2016 ◽  
Vol 200 ◽  
pp. 1-5 ◽  
Author(s):  
Wing Chung Chang ◽  
Emily Sin Kei Lau ◽  
Shirley Sanyin Chiu ◽  
Christy Lai Ming Hui ◽  
Sherry Kit Wa Chan ◽  
...  
2010 ◽  
Vol 117 (2-3) ◽  
pp. 280
Author(s):  
Verity Leeson ◽  
Eileen M. Joyce ◽  
Isobel Harrison ◽  
Thomas R.E. Barnes

2009 ◽  
Vol 107 (2-3) ◽  
pp. 232-237 ◽  
Author(s):  
Robert Bodén ◽  
Johan Sundström ◽  
Eva Lindström ◽  
Leif Lindström

1998 ◽  
Vol 43 (8) ◽  
pp. S11
Author(s):  
R.S. Goldman ◽  
R.M. Bilder ◽  
E. Pappadopulos ◽  
G. Reiter ◽  
J. Alvir ◽  
...  

2008 ◽  
Vol 99 (1-3) ◽  
pp. 182-191 ◽  
Author(s):  
Leanne M. Williams ◽  
Thomas J. Whitford ◽  
Gary Flynn ◽  
Wilson Wong ◽  
Belinda J. Liddell ◽  
...  

2006 ◽  
Vol 189 (4) ◽  
pp. 381-382 ◽  
Author(s):  
W. Cahn ◽  
N. E. M. van Haren ◽  
H. E. Hulshoff Pol ◽  
H. G. Schnack ◽  
E. Caspers ◽  
...  

SummaryProgressive brain volume changes have been reported in first-episode schizophrenia, but their relationship to the disease process or to other factors remains unclear. We examined such changes in the first year of illness, and related them to 5-year outcome. Progressive brain volume changes, in particular of grey matter, during the first year of illness were found to be significantly associated with clinical and functional outcome 5 years after the first episode. These findings suggest that early dynamic brain volume changes are related to the disease process and predict the longer-term outcome of schizophrenia.


2009 ◽  
Vol 40 (6) ◽  
pp. 935-944 ◽  
Author(s):  
C. González-Blanch ◽  
R. Perez-Iglesias ◽  
G. Pardo-García ◽  
J. M. Rodríguez-Sánchez ◽  
O. Martínez-García ◽  
...  

BackgroundIt has become widely accepted that cognitive deficits in schizophrenia are related to functional outcome. However, it remains to be seen whether these associations are relevant for predicting which cases will have a global functional recovery. In this study, we attempt to determine whether global functional recovery (integrating social and occupational outcomes) after first-episode schizophrenia (FES) can be predicted by cognitive variables.MethodA total of 131 FES patients with functional deficits (n=97) and functional recovery (n=34) as determined at 1-year follow-up were examined. Neuropsychological, sociodemographic, pre-morbid and clinical data at baseline were analysed using independent groups comparisons and a logistic regression method.ResultsSustained attention and negative symptoms emerged as significant predictors of good global functional outcome. Although the model revealed a high accuracy (91%) in the classification of patients with functional deficits, it was unacceptably low (26%) in the classification of patients with global functional recovery.ConclusionsThe limitations found in the prediction of a favourable global functional outcome may well be an indication for a need to address the role of other factors not commonly included in longitudinal studies of long-term outcomes in schizophrenia.


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