P3-428: Stability of nicotinic acetylcholine receptor binding in the frontal and temporal cortex of subjects with mild cognitive impairment

Receptor Binding ◽

Temporal Cortex ◽

Decreased cerebral α4β2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography

European Journal of Nuclear Medicine and Molecular Imaging ◽

10.1007/s00259-010-1644-5 ◽

2010 ◽

Vol 38 (3) ◽

pp. 515-525 ◽

Cited By ~ 78

Author(s):

Kai Kendziorra ◽

Henrike Wolf ◽

Philipp Mael Meyer ◽

Henryk Barthel ◽

Swen Hesse ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Positron Emission Tomography ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Acetylcholine Receptor ◽

Emission Tomography ◽

Nicotinic Acetylcholine ◽

Positron Emission

High Availability of the α7-Nicotinic Acetylcholine Receptor in Brains of Individuals with Mild Cognitive Impairment: A Pilot Study Using 18F-ASEM PET

Journal of Nuclear Medicine ◽

10.2967/jnumed.119.230979 ◽

2019 ◽

Vol 61 (3) ◽

pp. 423-426 ◽

Cited By ~ 1

Author(s):

Jennifer M. Coughlin ◽

Leah H. Rubin ◽

Yong Du ◽

Steven P. Rowe ◽

Jeffrey L. Crawford ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Pilot Study ◽

Acetylcholine Receptor ◽

High Availability ◽

Α7 Nicotinic Acetylcholine Receptor ◽

P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Cited By ~ 5

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia

The Journal of Clinical Psychiatry ◽

10.4088/jcp.16m11162 ◽

2018 ◽

Vol 79 (3) ◽

Cited By ~ 3

Author(s):

George M. Haig ◽

Deli Wang ◽

Jun Zhao ◽

Ahmed A. Othman ◽

Earle E. Bain

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Efficacy And Safety ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Chronic neonatal nicotine upregulates heteromeric nicotinic acetylcholine receptor binding without change in subunit mRNA expression

Brain Research ◽

10.1016/j.brainres.2006.06.084 ◽

2006 ◽

Vol 1113 (1) ◽

pp. 94-109 ◽

Cited By ~ 37

Author(s):

L.Z. Huang ◽

U.H. Winzer-Serhan

Keyword(s):

Mrna Expression ◽

Acetylcholine Receptor ◽

Receptor Binding ◽

Nicotinic Acetylcholine ◽

Subunit Mrna

Nudicauline and Elatine as Potent Norditerpenoid Ligands at Rat Neuronal α-Bungarotoxin Binding Sites: Importance of the 2-(Methylsuccinimido)benzoyl Moiety for Neuronal Nicotinic Acetylcholine Receptor Binding

Journal of Medicinal Chemistry ◽

10.1021/jm9604991 ◽

1996 ◽

Vol 39 (24) ◽

pp. 4860-4866 ◽

Cited By ~ 53

Author(s):

David J. Hardick ◽

Ian S. Blagbrough ◽

Gary Cooper ◽

Barry V. L. Potter ◽

Trevor Critchley ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Binding ◽

Binding Sites ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.07.021 ◽

2015 ◽

Vol 23 (17) ◽

pp. 5693-5701 ◽

Cited By ~ 1

Author(s):

Pauline W. Ondachi ◽

Zhuo Ye ◽

Ana H. Castro ◽

Charles W. Luetje ◽

M. Imad Damaj ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Binding ◽

Cycloxaprid Insecticide: Nicotinic Acetylcholine Receptor Binding Site and Metabolism

Journal of Agricultural and Food Chemistry ◽

10.1021/jf4030695 ◽

2013 ◽

Vol 61 (33) ◽

pp. 7883-7888 ◽

Cited By ~ 38

Author(s):

Xusheng Shao ◽

Tami L. Swenson ◽

John E. Casida

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Receptor Binding ◽

Receptor Binding Site ◽

Lower cortical Alpha4Beta2 nicotinic acetylcholine receptor binding and its relationship to cognitive dysfunction in early stage multiple sclerosis: A 2-[18F]F-A-85380 PET study

NeuroImage ◽

10.1016/j.neuroimage.2010.04.090 ◽

2010 ◽

Vol 52 ◽

pp. S111

Author(s):

Philipp M. Meyer ◽

Katharina Kurtz ◽

Eva Thomae ◽

Georg Becker ◽

Andreas Schildan ◽

...

Keyword(s):

Multiple Sclerosis ◽

Acetylcholine Receptor ◽

Cognitive Dysfunction ◽

Receptor Binding ◽

Early Stage ◽

PET imaging of acetylcholinesterase inhibitor-induced effects on α4β2 nicotinic acetylcholine receptor binding

Synapse ◽

10.1002/syn.21698 ◽

2013 ◽

Vol 67 (12) ◽

pp. 882-886 ◽

Cited By ~ 5

Author(s):

Ansel T. Hillmer ◽

Dustin W. Wooten ◽

Mohammed Farhoud ◽

Andrew T. Higgins ◽

Patrick J. Lao ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Binding ◽

Pet Imaging ◽

Acetylcholinesterase Inhibitor ◽